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Model gene-family birth-death dynamics across a species tree using CAFE5 (Mendes et al 2020 Bioinformatics 36:5516 gamma-distributed rate categories), CAFE5-error (annotation-error-aware), Count (Csurös 2010 ancestral state reconstruction), BadiRate (Librado 2012 likelihood + parsimony), DupliPHY-Family, and ALE/AleRax (for per-family DTL; see [[gene-tree-species-tree-reconciliation]]). Test lineage-specific gene-family expansions and contractions, distinguish biological dynamics from annotation artifacts, account for assembly fragmentation, identify functional enrichment in expanded / contracted families. Use when correlating gene-family changes with phenotype evolution, ranking lineages by adaptive gene-family-rate shifts, post-WGD dosage-balance analysis, or building Birth-death models from OrthoFinder presence/absence matrices.

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Queries myvariant.info BioThings aggregator for ClinVar, gnomAD, dbSNP, dbNSFP, COSMIC, CADD, and CIViC annotations in batched, version-tracked requests. Use when annotating variant lists from multiple databases simultaneously without managing per-source APIs, and when reproducibility-grade analyses require recording source data versions via _meta.

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Designs Bayesian clinical trials including Phase I dose-finding (BOIN, CRM, EWOC, mTPI-2), meta-analytic-predictive (MAP) priors with robust mixtures for external data borrowing, EXNEX for basket trials, hierarchical models for safety AE (Berry-Berry), Bayesian platform trials (I-SPY 2, GBM AGILE, REMAP-CAP), and posterior probability stopping rules. Covers FDA Bayesian Devices Guidance (2010), FDA Bayesian Methodology in Drugs Draft (January 2026), BOIN Fit-for-Purpose qualification (December 2021), and Project Optimus dose-optimisation. Use when designing dose-finding studies, platform trials, or sensitivity analyses with informative priors.

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This skill provides a way to retrieve information from the AgentScope library for analysis and decision-making.

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Create and train AI learning plugins with AgentDB's 9 reinforcement learning algorithms. Includes Decision Transformer, Q-Learning, SARSA, Actor-Critic, and more. Use when building self-learning agents, implementing RL, or optimizing agent behavior through experience.

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This skill confirms whether a hospital has the necessary policies and expertise to support inpatient insulin pump therapy, including informed consent, standardized order sets, and device management guidance for imaging and surgical procedures. Triggered by questions such as "Are hospital policies and expertise in place for insulin pump use?" to ensure safe continuation of pump therapy in noncritical illness.

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This skill guides clinicians to inform and counsel individuals seeking gender-affirming medical treatment about fertility preservation options before initiating puberty suppression in adolescents or before starting hormonal therapy in adolescents and adults. It is triggered when a patient is eligible for pubertal suppression or sex hormone treatment and is about to begin such therapy.

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Reassesses annually the patient’s ability to use CGM trend information to adjust insulin doses. Triggered by yearly CGM skills check or annual review of trend-based dosing competence.

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This skill provides structured education to patients and families about Cushing's syndrome pathophysiology, treatment options, and post-remission expectations. It is triggered when a clinician encounters a new Cushing's syndrome patient or family needing disease information, such as at initial diagnosis or before treatment initiation.

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Use when the user wants to design, redesign, shape, critique, audit, polish, clarify, distill, harden, optimize, adapt, animate, colorize, extract, or otherwise improve a frontend interface. Covers websites, landing pages, dashboards, product UI, app shells, components, forms, settings, onboarding, and empty states. Handles UX review, visual hierarchy, information architecture, cognitive load, accessibility, performance, responsive behavior, theming, anti-patterns, typography, fonts, spacing, layout, alignment, color, motion, micro-interactions, UX copy, error states, edge cases, i18n, and reusable design systems or tokens. Also use for bland designs that need to become bolder or more delightful, loud designs that should become quieter, live browser iteration on UI elements, or ambitious visual effects that should feel technically extraordinary. Not for backend-only or non-UI tasks.

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Automates browser interactions for web testing, form filling, screenshots, and data extraction. Use when the user needs to navigate websites, interact with web pages, fill forms, take screenshots, test web applications, or extract information from web pages.

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Discover and track emerging trends across Google Trends, Instagram, Facebook, YouTube, and TikTok to inform content strategy.

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Extract product data, prices, reviews, and seller information from any e-commerce platform using Apify's E-commerce Scraping Tool.

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Fetch any X/Twitter post as clean LLM-friendly JSON. Converts x.com, twitter.com, or adhx.com links into structured data with full article content, author info, and engagement metrics. No scraping or browser required.

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n8n workflow automation knowledge base. Provides n8n node information, node functionality details, workflow patterns, and configuration examples. Covers triggers, data transformation, data input/output, AI integration, covering 10 nodes. Keywords: n8n, workflow, automation, node, trigger, webhook, http request, database, ai agent.

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当用户需要做重大决策、团队存在群体思维、或想将决策权下放到一线时触发此技能。帮助建立知情指挥决策模型，让最有信息的人做最终决定。

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当用户犹豫是否分享敏感信息、询问领导者应该多透明、公司存在信息孤岛、或即将进行组织变革时触发。基于Netflix开卷管理哲学：默认公开一切。

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Code like Fable 5 — methodical, verified, and deeply informed by context. Use this skill whenever you need to write, edit, or create code.

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Find deepening opportunities in a codebase, informed by the domain language in CONTEXT.md and the decisions in docs/adr/. Use when the user wants to improve architecture, find refactoring opportunities, consolidate tightly-coupled modules, or make a codebase more testable and AI-navigable.

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Yuanbao (元宝) groups: @mention users, query info/members.

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Prices research, tests, surveys, dashboards and experiments before running them, by computing how much the result would raise expected utility - which is zero whenever no outcome would change the decision. Use when someone proposes an A/B test, user survey, market study, competitor analysis, analytics build, consultant, pilot, or "let's gather more data", and when deciding how large a study needs to be.

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Austin CapMetro transit — real-time vehicle positions, next arrivals, service alerts, route info, and trip planning for buses and rail.

日本語の概要は準備中です。原文の説明を表示しています。

CLI for AI agents to search and lookup anime info for their humans.

日本語の概要は準備中です。原文の説明を表示しています。

CLI for AI agents to search and lookup anime info for their humans.

日本語の概要は準備中です。原文の説明を表示しています。