「kage」の検索結果

Orders and orients assembled contigs into chromosome-scale scaffolds from long-range linking data, inserting N-gap spacers (adds no sequence). Covers Hi-C/Omni-C scaffolding (YaHS, SALSA2, 3D-DNA/Juicer), Hi-C read-mapping prerequisites (map each end separately, no mate rescue, dedup, enzyme-aware), reading the contact map for misjoins/inversions/false-duplications, manual curation in Juicebox/PretextView (the VGP/DToL standard), reference-guided scaffolding (RagTag) and its karyotype-erasure hazard, genetic-map (ALLMAPS) and Bionano optical-map integration, chimera-breaking before scaffolding, gap-filling, and telomere/contig-vs-scaffold-N50 QC (tidk). Use when turning contigs into chromosomes with Hi-C, integrating a linkage map or optical map, choosing a scaffolder by available linking data, or judging whether a chromosome-scale assembly is trustworthy.

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Build clustered heatmaps for expression matrices and other features-by-samples data with rigorous distance/linkage/scaling choices, robust color mapping, optimal leaf ordering, and ComplexHeatmap/pheatmap/seaborn rendering. Covers the ward.D vs ward.D2 trap, the row-vs-column scaling decision, multi-track annotations, oncoPrint, and raster rendering for large matrices. Use when visualizing expression patterns across samples or identifying co-regulated clusters.

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Resolve the architecture of focal oncogene amplifications — extrachromosomal DNA (ecDNA), breakage-fusion-bridge (BFB) cycles, homogeneously staining regions (HSR), and linear amplification — from whole-genome sequencing with AmpliconArchitect, the AmpliconSuite pipeline, and AmpliconClassifier. Covers copy-number seed selection, breakpoint-graph reconstruction, balanced-flow optimization, ecDNA classification, and the limits of depth-only amplification calls. Use when a focal amplification needs structural characterization, when distinguishing ecDNA from chromosomal amplification, suspecting ecDNA-driven oncogene amplification or therapy resistance, or selecting copy-number seeds for amplicon reconstruction.

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Performs subgroup and heterogeneous treatment effect (HTE) analyses for clinical trials. Covers Mantel-Haenszel pooling, Breslow-Day, interaction tests in regression, RERI for additive interaction, modern data-adaptive HTE methods (STEPP, SIDES, causal forests, X/R-learners), Bayesian shrinkage (Dixon-Simon, MAP, EXNEX), graphical multiplicity (Bretz-Maurer), and credibility frameworks (Sun BMJ, EMA 2019). Use when analyzing treatment effects across patient subgroups for regulatory submissions or precision-medicine claims.

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Run build, deploy, inspect, and fix loops for .NET MAUI apps that already have MAUI DevFlow integrated. USE FOR: launching MAUI apps, selecting devices or emulators, waiting for or recovering agent connections, broker/port/adb connectivity issues, visual tree inspection, screenshots, UI interaction, Blazor WebView CDP debugging, reading DevFlow logs, and iterative app debugging. DO NOT USE FOR: first-time DevFlow package setup (use maui-devflow-onboard), or generic desktop automation unrelated to MAUI. INVOKES: maui devflow CLI, dotnet CLI, Android adb/android tools, and Apple simctl tools.

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Use this skill when the user asks about CDL driver wellness, retention strategies, what causes driver turnover, common health issues (obesity, hypertension, sleep apnea, mental health), benefits packages, home-time policies, and how to build a culture that keeps drivers. Reference ATA Workforce Development + FMCSA Wellness Initiative.

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Refine UI posture — improve an existing screen without reinventing it. Use when the current page is roughly right but needs polish (hierarchy, spacing, labels, loading/empty/error states, mobile breakage), or when consistency with the rest of the app matters more than novelty.

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Detects leaky abstractions in PHP code. Identifies implementation details exposed in interfaces, concrete returns from abstract methods, framework leakage into domain, and infrastructure concerns in application layer.

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Create handoff packages for session transitions. Use when ending sessions, preparing for continuation, saving session state, or creating resumable context.

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Connect to Azure Database for PostgreSQL Flexible Server from Node.js/TypeScript using the pg (node-postgres) package.

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Astropy is the core Python package for astronomy, providing essential functionality for astronomical research and data analysis.

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Actorization converts existing software into reusable serverless applications compatible with the Apify platform. Actors are programs packaged as Docker images that accept well-defined JSON input, perform an action, and optionally produce structured JSON output.

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Use this skill when importing Excel, CSV, or pasted rows with nuxt-ui-tools as a package consumer. Covers defineSpreadsheetSchema (typed context, chained text/number/date/boolean/select columns, columns depending on the columns above (options, defaults, rules per row), groups and dynamic groups built from the context, exact matching, option sources shared with forms, unknown-value policies, rules and levels, validate, row identity with duplicates and stored records, output), useSpreadsheetImport (headless models, onSubmit with batches and rejections), the UiSpreadsheetImport* parts, useSpreadsheetSteps with custom steps, and the ready-made UiSpreadsheetImport wizard.

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Use this skill when building or debugging table usage with nuxt-ui-tools as a package consumer. Covers defineTableSchema, useTable, DataList, granular composition, columns, filters, sorting, offset or cursor loading, layouts, summary rows on phones, first-use empty states, actions, selection, accessible row names, context, and URL state with concrete examples.

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Use this skill when wiring nuxt-ui-tools translations in an app. Covers UiToolsProvider, locale objects, lazy schema text, and how package-owned UI copy differs from schema-owned text.

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Use this skill when previewing files with nuxt-ui-tools as a package consumer. Covers mounting UiFilePreviewProvider, opening one file or a gallery with useFilePreview() or useNuxtApp().$filePreview, file descriptors (URL, File/Blob, or a function that returns a signed URL), options (index, mode, gallery, loop, pdf page, callbacks), the returned handle, the built-in renderers (image, video, audio, PDF, text/JSON, CSV, Markdown, Office and archive fallbacks), renditions, download and custom header actions, the markdown render hook, custom renderers with defineFilePreviewRenderer and UiFilePreviewTools, theming tokens, and how the upload field uses the preview.

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Use this skill when building or debugging URL-backed state with nuxt-ui-tools as a package consumer. Covers codecs, useQueryState, useQueryStates, dynamicQueryState, grouped state, dynamic keys, and practical query-string examples.

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Use this skill when building analytics dashboards with nuxt-ui-tools as a package consumer. Covers schema and view functions (defineDashboardSchema, defineDashboardView) that take their context as typed params, useDashboard with a getter that rebuilds on input change, typed injection (useDashboardView, injectDashboard, InferDashboard, InferDashboardView), filters declared inline with the f builder and synced with the URL, memory, or an external store (one value per key across views), headless filters, filter controls and the shipped UI (UiDashboardPage, UiDashboardFilters, UiDashboardFilter, UiDashboardViewTabs) with slot overrides, remote paginated pickers and remoteTableOptions, staged queries (essential / background / deferred) with select and dependent requires, lazy enabled conditions on views, queries, and filters (blocks of disabled queries hidden, grids closing up), derived values, views (tabs), query-scoped filters, number formats (presets, Intl options, useDashboardFormat), and the dashboard blocks (stats with trends, goals, and comparisons, stat groups, gauges, unovis charts with highlights, value labels, and totals, lists with progress rings, bars, funnel, alerts, activity feeds, sortable tables, custom widgets) with their automatic loading, error, empty, and refresh states, card menus, header and footer actions, row actions, drill-down and selected state, card tabs, split cards, comparison periods, auto-refresh, and data freshness.

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Use this skill for internal i18n work in this repository. Covers locale ownership, provider wiring, lazy schema text contracts, and the maintenance surfaces that must stay in sync when package or playground translations change.

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Use this skill when working with the nuxt-ui-tools form runtime as a package consumer. It covers schema-driven forms, the provider-backed form API, inline rendering, overlay rendering, form pages with a section navigation, choice cards, and typed submit results.

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Creates interactive educational MicroSims using the best-matched JavaScript library (p5.js, Chart.js, Plotly, Mermaid, vis-network, vis-timeline, Leaflet, Venn.js). Analyzes user requirements to route to the appropriate visualization type and generates complete MicroSim packages with HTML, JavaScript, CSS, documentation, and metadata.

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Work with state-of-the-art machine learning models for NLP, computer vision, audio, and multimodal tasks using HuggingFace Transformers. This skill should be used when fine-tuning pre-trained models, performing inference with pipelines, generating text, training sequence models, or working with BERT, GPT, T5, ViT, and other transformer architectures. Covers model loading, tokenization, training with Trainer API, text generation strategies, and task-specific patterns for classification, NER, QA, summarization, translation, and image tasks. (plugin:scientific-packages@claude-scientific-skills)

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Use this skill when working with scientific research tools and workflows across bioinformatics, cheminformatics, genomics, structural biology, proteomics, and drug discovery. This skill provides access to 600+ scientific tools including machine learning models, datasets, APIs, and analysis packages. Use when searching for scientific tools, executing computational biology workflows, composing multi-step research pipelines, accessing databases like OpenTargets/PubChem/UniProt/PDB/ChEMBL, performing tool discovery for research tasks, or integrating scientific computational resources into LLM workflows.

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Design irresistible offer packages with real salary benchmarks, negotiation playbooks, and competitive counter-strategies. Co-designed with Siku (司库). Includes total compensation calculator, negotiation scripts, and BATNA analysis.

日本語の概要は準備中です。原文の説明を表示しています。