「pair」の検索結果

Build whole-genome alignments using Progressive Cactus (Armstrong 2020 reference-free clade-level WGA), Minigraph-Cactus (Hickey 2024 pangenome-aware), LASTZ chain/net (UCSC pipeline), MUMmer4 (Marçais 2018 pairwise), minimap2 -x asm5/10/20 (Li 2018 fast pairwise), AnchorWave (Song 2022 WGD-aware), and Mauve / progressiveMauve (bacterial). Operates the HAL toolkit (Hickey 2013) for downstream extraction including halSynteny, halLiftover, halBranchMutations, and hal2maf. Use when constructing multi-species alignments for comparative-annotation projection (TOGA), synteny detection, conservation analyses (phyloP / PhastCons), or pangenome graph construction; selecting between reference-free (Cactus) and reference-anchored (LASTZ chains/nets) approaches; tuning sensitivity for closely vs distantly related genomes; or producing HAL files for genome-wide downstream tools.

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Identify direct miRNA-target interactions from AGO HITS-CLIP, AGO-CLEAR-CLIP (chimeric reads), HEAP (Halo-Ago2 mouse), chimeric eCLIP / miR-eCLIP (deep miRNA-target profiling), or CLASH using chimeric-read processing pipelines, seed-pairing analysis, and 3' auxiliary pairing rules. Use when distinguishing direct miRNA targets from indirect, integrating CLIP-derived target maps with TargetScan / miRDB / DIANA predictions, applying canonical 7mer-8mer seed matching with 3' UTR context, or recovering miRNA-mRNA chimeras at scale.

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Process and analyze single-cell ATAC-seq data with Signac, ArchR, SnapATAC2, or Cell Ranger ATAC. Use when handling 10X scATAC or 10X Multiome (paired RNA+ATAC) data, performing per-cell QC, choosing between ArchR/Signac/SnapATAC2 ecosystems, building per-cluster consensus peaksets, integrating with paired scRNA-seq, doublet detection (AMULET vs ArchR vs scDblFinder), or running pseudobulk differential accessibility per cluster.

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Infer cis-regulatory connections (peak-to-peak co-accessibility) from scATAC-seq using Cicero, ArchR getCoAccessibility, or SCENIC+. Use when linking enhancer accessibility to promoter accessibility, identifying enhancer-gene pairs from chromatin alone (without paired RNA), running gene-regulatory inference combining ATAC + RNA, or comparing predicted regulatory contacts against Hi-C/Micro-C ground truth.

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Resolve repository documentation authority, repair reading paths and explanations, or shape a bounded public projection. Maintain docs after a bounded change when indirect reader promises, generated or paired sources, version/evidence boundaries, or unclear authority need attention. Ordinary known updates stay in normal development; not for isolated prose polishing, code review, or broad runtime audits.

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Adaption AI SDK for synthetic data augmentation and dataset adaptation. Use when building data pipelines with the Adaption Python SDK, uploading datasets (local files, Hugging Face, Kaggle), running augmentation/adaptation jobs, configuring brand controls (hallucination mitigation, safety categories, length), recipe specifications (reasoning traces, deduplication, preference pairs, prompt rephrase), evaluating dataset quality, downloading results, or any workflow involving `pip install adaption`, `from adaption import Adaption`, Adaptive Data, or the adaptionlabs.ai API. Also trigger when the user mentions synthetic data generation for fine-tuning, dataset augmentation pipelines, DPO preference pair generation, or grounding-based hallucination reduction on training data.

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Solves complex, open-ended problems using a knockout tournament mechanism. Generates an initial population of diverse candidate answers, pairs them into head-to-head matches, produces a hybrid "child" solution from each pair, and advances the best of the three through a bracket until a winner emerges. Use this skill whenever the user wants to competitively select the best answer from a field of alternatives, asks for a "tournament" or "bracket" style search, wants a faster alternative to full evolutionary search, or uses phrases like: "run a tournament on this", "bracket-style search", "let solutions compete", "knockout search", "find the best answer by elimination", or "which solution wins?". Also trigger when the problem is open-ended and the user wants a clear winner quickly rather than a deep multi-generation refinement.

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UI/UX design intelligence. 67 styles, 96 palettes, 57 font pairings, 25 charts, 13 stacks (React, Next.js, Vue, Svelte, SwiftUI, React Native, Flutter, Tailwind, shadcn/ui). Actions: plan, build, create, design, implement, review, fix, improve, optimize, enhance, refactor, check UI/UX code. Projects: website, landing page, dashboard, admin panel, e-commerce, SaaS, portfolio, blog, mobile app, .html, .tsx, .vue, .svelte. Elements: button, modal, navbar, sidebar, card, table, form, chart. Styles: glassmorphism, claymorphism, minimalism, brutalism, neumorphism, bento grid, dark mode, responsive, skeuomorphism, flat design. Topics: color palette, accessibility, animation, layout, typography, font pairing, spacing, hover, shadow, gradient. Integrations: shadcn/ui MCP for component search and examples.

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Diagnose and restore the Claude Desktop app when it will not start, crashes, or runs with no visible window. Use for Windows MSIX launch failures, 'Not main instance', stale AppX job containers, NeedsRemediation or 0x80070020 errors. Separates Desktop from the CLI, reads fresh logs, picks a narrow fix and proves a visible working window. Triggers: /claude-repair, Claude Desktop won't open, Claude app crashed.

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Repair and triage guide for the NV oOS PHPUnit test suite — Docker test environment (incl. cross-worktree one-off runners), CI log triage, and 71 recurring root-cause patterns (hook resets, singleton interference, WP_Error envelope drift, coverage-manifest drift, preset-accounting gaps, and more — see the patterns section). Covers the cluster-by-cluster PR workflow against alpha-working and validation gates. Use when fixing failing PHPUnit tests, triaging CI logs, repairing test drift, deciding between a production fix and a test fix, or starting a new fix cluster.

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新規・変更 skill の fixture/eval と、WITH/WITHOUT の paired ablation による限界寄与の評価可能性を確認し、activation と effectiveness を分離して案内する。

Train or fine-tune sentence-transformers models across `SentenceTransformer` (bi-encoder, dense or static embedding model for retrieval, similarity, clustering, classification, paraphrase mining, dedup, multimodal), `CrossEncoder` (reranker, pair scoring for two-stage retrieval / pair classification), `SparseEncoder` (SPLADE, sparse embedding model for learned-sparse retrieval), and `MultiVectorEncoder` (ColBERT / late-interaction, per-token embeddings scored with MaxSim). Covers loss selection, hard-negative mining, evaluators, distillation, LoRA, Matryoshka, and Hugging Face Hub publishing. Use for any sentence-transformers training task.

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Manage Telegram channel access — approve pairings, edit allowlists, set DM/group policy. Use when the user asks to pair, approve someone, check who's allowed, or change policy for the Telegram channel.

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Expert en DIY et making (3D printing, Arduino, woodworking, electronics, repair)

日本語の概要は準備中です。原文の説明を表示しています。

Expert Aider (AI pair programming, git integration, multi-model, architecture)

日本語の概要は準備中です。原文の説明を表示しています。

Diagnose App Store submission blockers and operate review health with asc, including readiness validation, repair routing, status monitoring, cancellation, and retry decisions. Use when validation fails, a version is not in a valid state, review status is unclear or stuck, or a failed submission must be repaired and retried. For staging, upload, publication, and submission execution, use asc-release-flow.

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Insurance-industry App-in-Skill for read-only data governance, backed by an operator-provisioned Busabase workspace (one Drive node for the file drive plus four Bases for QA pairs, featured information, insurer notices, and user feedback) and trusted export/restore/PDF-text-backfill scripts. Use when the user invokes $kelly-insure-data or /kelly-insure-data, wants an insurance data workspace with UI, needs to review insurance files, metadata completeness, QA pairs, featured information, insurer notices, or user feedback, wants to back up or restore a Kelly Insure Data Busabase workspace from local PDFs, or wants Busabase Drive/Base data surfaced for data quality review and ongoing data governance.

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Evaluate LLM outputs using frontier models as judges. Use for pairwise model comparison, quality scoring with custom rubrics, and automated evaluation pipelines. Covers position bias mitigation, statistical significance, and generating preference data for DPO/RLHF.

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End-to-end Hi-C analysis workflow from FASTQ to compartments, TADs, and loops, with the decision of WHICH features the sequencing depth can support. Covers pairtools read-pair processing and library QC, cooler matrices, ICE balancing and distance-decay expected, A/B compartments, TAD boundaries, loop calling, and the routing of HiChIP/PLAC-seq/Capture Hi-C to protein-directed loop callers. Use when processing Hi-C data end to end, deciding a resolution for a given depth, or choosing between bulk-Hi-C and protein-directed loop calling.

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Rust 製 AI/ML ライブラリ fandhe-ai のリファレンス。Burn / candle / tch 非依存の from-scratch 実装。 compat::Sequential, compat::array, tape(), tape_for(), Tape, Var, Tensor, Gradients, LinearVars, Device (Cpu / Cuda / Metal)。 tensor-core の kernel fusion, FusionPlan, BackendOps。dynamic-tape autodiff。 cfg ベースのバックエンド構成・数値一致契約。ONNX / safetensors 相互運用。 guardrail / self-repair CLI。

The perception-by-culture lens for psycho-logic — establish HOW a specific region, country, or subculture reads a signal before you send it, because perception is culturally coded and the same move can mean the opposite elsewhere. Use when adapting a product, price, message, or campaign to a new market; when the user asks 'will this work in [country/region]', 'why does this land in X but flop in Y', 'how do people here perceive Z', 'how do we localise/differentiate by region', or is about to copy a US/global playbook into another market. Covers the cultural dimensions that move Sutherland's levers — uncertainty avoidance, individualism/collectivism, status/power distance, high- vs low-context communication, mental-accounting norms, trust locus, and taboo/sacredness — and how each rewires reframing, costly-signaling, and experience-design. Inspired by Rory Sutherland's *Alchemy*. Routed to from psycho-logic; pair with market-recon for live local data. 日本語・中文の相談（「この地域で通用する？」「适合本地市场吗？」）にも使う。

The live fieldwork layer for psycho-logic — go look at the actual target market NOW instead of reasoning from your training-data stereotype of it. Use when a psycho-logic move needs grounding in a specific place: the user asks 'what do competitors in [region/country] actually do', 'what's the real price band / norm here', 'how do local leaders position themselves', 'research this market before we localise', 'what signals trust to buyers in X', or is about to launch/adapt in a market you haven't studied. Runs structured web research in the local language — local competitors and their signals, price bands, category conventions, review/trust sources, local terminology, taboos and regulations — and synthesises a compact perception profile the four moves consume. Inspired by Rory Sutherland's *Alchemy*. Routed to from psycho-logic; pair with cultural-context (the lens that tells you what to look for). 日本語・中文の相談（「現地の実態を調べて」「调研当地市场」）にも使う。

Bulk mode — maximum development speed by spending tokens aggressively on massive parallel sub-agents and multi-agent workflows, while the orchestrator context stays lean (pairs with /slim). Invoking /bulk is the user's explicit opt-in to Workflow/ultracode-style orchestration for this session. Use when the user types /bulk, asks for "爆速", "並列で大量に", "ultracode", "多エージェント", or hands over a big task where wall-clock speed matters more than token cost.

Loads, converts, and manipulates Hi-C contact matrices in cooler format (.cool/.mcool/.scool) and Juicer .hic, using cooler (Python + CLI), hic2cool, and hictk. Covers the single-resolution mcool URI (file.mcool::/resolutions/<bp>), the load-bearing divisive-vs-multiplicative weight-naming rule (KR/VC/VC_SQRT auto-divisive vs cooler's multiplicative weight), what survives .hic<->.cool conversion (FRAG matrices and norm vectors do not), raw-vs-balanced coarsening, the .pairs upper-triangle/chromsize-order contract, and chrom-naming/bin-table provenance. Use when loading a cooler, converting .hic to .mcool, selecting a resolution, building a cooler from pairs or a matrix, coarsening/zoomifying, importing Juicer norm vectors, or debugging all-NaN balanced matrices and chr1-vs-1 empty fetches.

日本語の概要は準備中です。原文の説明を表示しています。