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概要と使いどころ
Write B2B cold emails and follow-up sequences that get replies. Use when the user wants to write cold outreach emails, prospecting emails, cold email campaigns, sales development emails, or SDR emails. Covers subject lines, opening lines, body copy, CTAs, personalization, and multi-touch follow-up sequences.
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Estimates differential gene expression for short read sequence count using methods appropriate for count data. If you have paired data you may also want to consider Tophat/Cufflinks. Input must be raw count data for each sequence arranged i
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A first step in the data analysis of Mass Spectrometry (MS) based proteomics data is to identify peptides and proteins. With this respect the huge number of experimental mass spectra typically have to be assigned to theoretical peptides derived from a sequence database. Search engines are used for this purpose. These tools compare each of the observed spectra to all candidate theoretical spectra derived from the sequence data base and calculate a score for each comparison. The observed spectrum
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Memory efficient string containers, string matching algorithms, and other utilities, for fast manipulation of large biological sequences or sets of sequences.
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seqLogo takes the position weight matrix of a DNA sequence motif and plots the corresponding sequence logo as introduced by Schneider and Stephens (1990).
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Adds Smartlead-compatible spintax to cold email sequences for deliverability. Use this skill whenever the user asks to add spintax, spin text, add variations, or improve deliverability of email copy — especially when they mention Smartlead, cold email sequences, or paste HTML email content. Also trigger when the user says "spintax", "spin", "variations", "deliverability spintax", or references adding randomized alternatives to email copy. Works with both plain text and HTML input.
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Guides users through professional filmmaking workflows in Higgsfield Cinema Studio, including creating multi-shot sequences, configuring optical stacks, applying color grading, managing Soul Cast AI actors, and structuring per-scene prompts with Director Panel camera movements. Use when the user mentions Cinema Studio, Cinema Studio 2.5, Cinema Studio 3.0, Cinema Studio 3.5, Cinema Studio 4.0 (`cinematic_studio_video_4_0` — its four modes, camera/lens/aperture/era/genre/pacing ids, light presets, color palette), Soul Cast, color grading, multi-shot video, shot sequences, storyboard workflow, Hero Frame, optical stack, keyframe interpolation, Elements system (@Characters/@Locations/@Props), Speed Ramp, Director Panel, Higgsfield Popcorn, Single Shot / Multi-Shot Auto / Multi-Shot Manual modes, Reference Anchor, Smart shot control, or any professional filmmaking workflow inside Higgsfield.
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Use when the user needs B2B pipeline work — ICP and account lists, prospecting, cold email and LinkedIn outbound sequences, lead scoring, MQL to SQL handoff, sales decks, objection handling, demo scripts, CRM pipeline hygiene, and RevOps reporting. Trigger on 'find leads', 'prospect list', 'cold email sequence', 'outbound campaign', 'lead scoring model', 'our pipeline is empty', 'sales deck for enterprise buyers'. Also use when the user has a strong product and no route to the companies that need it. Not for — consumer lifecycle email, see `14-email-marketing-global`; the offer being sold, see `31-offer-design-global`; positioning against rivals, see `58-positioning-global`; inbound content, see `36-content-brief-global`.
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Use when you need to generate Java project diagrams — including UML sequence diagrams, UML class diagrams, C4 model diagrams, UML state machine diagrams, UML Deployment Diagrams, ER (Entity Relationship) diagrams, and bounded-context diagrams — through a modular, step-based interactive process that adapts to your specific visualization needs. This should trigger for requests such as Generate UML diagram; Create sequence diagram; Create class diagram; Create state machine diagram; Create deployment diagram; Create C4 diagram; Create bounded-context diagram; Create context-map diagram. Part of Plinth Toolkit
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Build personalized cold outreach sequences for LinkedIn and email. Use when someone needs to reach prospects, warm up cold leads, or build a systematic outreach engine. Covers research, connection requests, follow-ups, and conversion.
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Create animated, explorable editorial diagrams in 45 types (architecture, flowchart, sequence, state, ER, DB schema, UML class, swimlane, timeline, gantt, journey, tree, org chart, nested, venn, quadrant, fishbone, wardley, bar, line, scatter, sankey, treemap, heatmap, 3D isometric objects, floor plans and exploded views) as standalone HTML from a short JSON spec. Use when the user asks to draw, diagram, chart or visualize a system, codebase, flow, process, API call sequence, hierarchy, data or a physical object (a chair); to convert Mermaid, Graphviz/DOT, PlantUML, D2, draw.io, Excalidraw, SQL or CSV into a clean diagram; or to export a diagram as PNG, JPEG, SVG, GIF or MP4. Also for everyday plans: trips, moves, job hunts, approvals, budgets, where money goes.
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Comprehensive toolkit for protein language models including ESM3 (generative multimodal protein design across sequence, structure, and function) and ESM C (efficient protein embeddings and representations). Use this skill when working with protein sequences, structures, or function prediction; designing novel proteins; generating protein embeddings; performing inverse folding; or conducting protein engineering tasks. Supports both local model usage and cloud-based Forge API for scalable inference.
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Cloud laboratory platform for automated protein testing and validation. Use when designing proteins and needing experimental validation including binding assays, expression testing, thermostability measurements, enzyme activity assays, or protein sequence optimization. Also use for submitting experiments via API, tracking experiment status, downloading results, optimizing protein sequences for better expression using computational tools (NetSolP, SoluProt, SolubleMPNN, ESM), or managing protein design workflows with wet-lab validation.
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Query UCSC Genome Browser REST API for DNA sequences, tracks, gene models, and conservation across 100+ assemblies. Retrieve sequence by region, list/fetch BED/bigWig tracks, chromosome sizes, RefSeq/GENCODE gene structures, PhyloP/PhastCons scores. Use for UCSC annotations; Ensembl REST API for Ensembl gene IDs and VEP variant annotation.
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Query RCSB PDB (200K+ structures) via the public REST + GraphQL APIs with plain `requests` (no SDK). Search by text, attribute, sequence, or 3D structure similarity (Search API); retrieve metadata via GraphQL (Data API); download PDB/mmCIF from files.rcsb.org. For AlphaFold predictions use alphafold-database-access; for protein sequences only use uniprot-protein-database.
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Biopython sequence analysis: parse FASTA/FASTQ/GenBank/GFF (SeqIO), NCBI Entrez (esearch/efetch/elink), remote/local BLAST, pairwise/MSA alignment (PairwiseAligner, MUSCLE/ClustalW), phylogenetic trees (Phylo). Use for gene family studies, phylogenomics, comparative genomics, NCBI pipelines. For PCR/restriction/cloning use biopython-molecular-biology; for SAM/BAM use pysam.
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Protein language models (ESM3, ESM C) for sequence generation, structure prediction, inverse folding, and embeddings. Design novel proteins, extract ML features, or fold sequences. Local GPU or EvolutionaryScale Forge API. Use AlphaFold for traditional folding; RDKit for small molecules.
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ランディングページ、ホームページ、料金ページ等のマーケティングコピーを作成・改善するスキル。 「コピーを書いて」「LPのコピー作成」「ヘッドライン考えて」等のリクエストで発動。 For email copy, see email-sequence. For popup copy, see popup-cro.
Kinetic typography, logo animations, and stylized motion design skill. **Triggers when:** - User wants text animations or kinetic typography - Request involves logo reveals or title sequences - Content focuses on visual impact over education - User mentions "title", "intro", "logo", "text animation", "kinetic" **Capabilities:** - Kinetic typography with dynamic text effects - Logo reveals and brand animations - Particle effects and visual flourishes - Modern motion design patterns - Attention-grabbing title sequences
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Create diagrams and visualizations using Mermaid syntax. Use when generating flowcharts, sequence diagrams, class diagrams, entity-relationship diagrams, Gantt charts, or any visual documentation. Triggers on Mermaid, flowchart, sequence diagram, class diagram, ER diagram, Gantt chart, diagram, visualization.
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Restructure existing code without changing its behavior, through a test-gated refactoring loop: a named target, a green suite over that target before any edit, a planned sequence of small named refactorings, and the full suite re-run after every step. Use when the user wants to refactor, restructure, clean up, simplify, or improve the design of existing code, or to apply refactoring recommendations from a code-review or architectural-analysis report. This skill changes code; it does not review code (use code-review), assess architecture (use architectural-analysis), plan a multi-module restructure before executing it (use plan-a-change), map domain boundaries before restructuring along them (use ddd-analysis), or build new behavior test-first (use tdd). Do not use it on code inside an active tdd loop; the refactor step of tdd owns that cleanup. Runs its planned sequence to completion without pausing for review; to review each named refactoring as it lands, use pairing.
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Splits a body of context into a sequence of vertical-slice build phases where each phase is independently demonstrable to a real user and each builds on the previous. Use when the user wants to plan, sequence, phase, slice, break down, or order the build of a feature, capability, system, or initiative, and produces a plain-language phased build outline. Does not produce implementation detail — use plan-implementation. Does not specify behavior that has not been decided — use plan-a-feature. Does not perform gap analysis between two artifacts — use gap-analysis. Does not break a plan into independently-grabbable work items — use plan-work-items.
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Find leads matching criteria and bulk-add them to an Apollo outreach sequence. Handles enrichment, contact creation, deduplication, and enrollment in one flow.
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Design multi-touch outbound email sequences with personalized messaging, timing cadences, and conversion-aware copy for prospecting or re-engagement. Use when the user needs a coordinated sales campaign across several touches; use email-drafting for a single message or reply.
日本語の概要は準備中です。原文の説明を表示しています。