「ast」の検索結果

Designs adaptive clinical trials including group-sequential (O'Brien-Fleming, Pocock, Lan-DeMets spending), sample-size re-estimation (blinded Friede-Kieser, unblinded Cui-Hung-Wang, Mehta-Pocock promising zone), seamless Phase 2/3 with treatment-arm selection, population enrichment, and response-adaptive randomisation. Covers FDA 2019 Final Adaptive Designs Guidance, FDA 2022 Master Protocols, and ICH E20 Step 2b/3 draft (June 2025, NOT final). Use when planning interim analyses, sample-size re-estimation, or master/platform-trial designs.

日本語の概要は準備中です。原文の説明を表示しています。

docs (editable docs people share and comment on; the default for any document, named as a doc or not: a document, report, proposal, resume, cover letter, letter, contract, policy, form, template, worksheet, essay, handbook, guide, how-to, cheat sheet, SOP or other writing to keep, share, collaborate on, send, submit, print or sign; a doc exports to Word, PDF, Markdown or Google Docs, so needing a file to send, attach, upload, submit or print is no reason to pick Word, and a file nobody asked for is a doc, not Word; a plan, comparison, summary or notes asked in chat stays in chat; a pasted claude.ai artifact link may be a doc: check with docs tools first; Word or another file format named, tracked changes wanted, or a .docx to change or use as a template → that format's skill): making one → if no docs-connector instructions are in context, call its `guide` (topic.instructions) first; then create the doc (headings only, no body) before any search, file read or plan, even with files attached.

日本語の概要は準備中です。原文の説明を表示しています。

Security audit, hardening, threat modeling (STRIDE/PASTA), Red/Blue Team, OWASP checks, code review, incident response, and infrastructure security for any project.

日本語の概要は準備中です。原文の説明を表示しています。

Rebuild the vault dependency graph (_graph.md) via the deterministic generator script. /graph forces a full rebuild; /graph last (run after every /sync) rebuilds only if the vault changed; /graph [N] is treated as last. The generator reads the vault and writes _graph.md directly, so the file never streams through a model response.

日本語の概要は準備中です。原文の説明を表示しています。

Rebuild the vault dependency graph (_graph.md) via the deterministic generator script. $graph forces a full rebuild; $graph last (run after every $sync) rebuilds only if the vault changed; $graph [N] is treated as last. The generator reads the vault and writes _graph.md directly, so the file never streams through a model response.

日本語の概要は準備中です。原文の説明を表示しています。

Expert guidance for fast fine-tuning with Unsloth - 2-5x faster training, 50-80% less memory, LoRA/QLoRA optimization

日本語の概要は準備中です。原文の説明を表示しています。

Review only changes since last commit using impact analysis. Token-efficient delta review with automatic blast-radius detection.

日本語の概要は準備中です。原文の説明を表示しています。

Estima, confirma e acompanha o gasto com geradores pagos. Use quando o usuário disser "quanto vai custar", "orçamento", "quanto gastei", "controlar custo", "está caro", antes de qualquer lote de geração, ou ao fechar campanha. Com APIs no centro, custo deixa de ser detalhe e vira restrição de projeto.

日本語の概要は準備中です。原文の説明を表示しています。

Analisa custo AWS e identifica desperdício em EC2, RDS, S3, EKS, EBS, Elastic IP, NAT Gateway e tráfego. Use quando o usuário disser "custo", "fatura", "está caro", "FinOps", "reduzir gasto AWS", "Cost Explorer", "otimizar custo". Quase todo leitura — seguro por natureza.

日本語の概要は準備中です。原文の説明を表示しています。

Backup, restore, snapshot, PITR, retenção e plano de recuperação de desastre — S3, Glacier, RDS, PBS, pg_dump, WAL. Use quando o usuário disser "backup", "restore", "restaurar", "snapshot", "PITR", "desastre", "DR", "RTO", "RPO", "perdemos dado".

日本語の概要は準備中です。原文の説明を表示しています。

Generates a polished, leadership-ready performance briefing with KPI tiles, executive narrative bullets, and a driver analysis — all as a print-ready HTML document. Always use this skill when someone asks for an executive summary, performance briefing, leadership readout, stakeholder update, or business review — even if they don't say "executive" explicitly. Trigger phrases include: "write a summary of last week's performance," "create a briefing for our leadership team," "produce a monthly business review," "what should I tell executives about our metrics," "generate a performance narrative," "QBR summary," "weekly business review," "board update," "stakeholder briefing," "how did we do last week," or "give me a performance snapshot." When in doubt, use this skill — it is always better to produce a polished briefing than a raw data dump.

日本語の概要は準備中です。原文の説明を表示しています。

Clean editorial-style interfaces. Warm monochrome palette, typographic contrast, flat bento grids, muted pastels. No gradients, no heavy shadows.

日本語の概要は準備中です。原文の説明を表示しています。

Bootstrap full agent infrastructure for an existing, already-coded project without modifying a single line of source code. Surveys the repo, infers conventions from manifests, README, git history, and source samples, then generates the missing AGENTS.md, docs/architecture.md, docs/product-soul.md, ADR backfill, and seeded docs/memory/ files. Asks the user only about gaps the repo cannot reveal. Load when the user asks to "retroactive project setup", "backfill agent infrastructure", "bootstrap agents for this existing repo", "onboard agents to a legacy codebase", "set up agents without touching code", or "fill in missing agent context for this project".

日本語の概要は準備中です。原文の説明を表示しています。

Review a built frontend against its chosen direction, catch drift back to generic AI defaults, enforce state coverage, ethical patterns, UX heuristics, and polish, and check contrast with APCA (not the legacy WCAG ratio). Produces specific, prioritized fixes — never vibes-based feedback. Works with pasted screenshots or Playwright MCP automated capture. Load when the user asks to review a UI, audit a design, check if a frontend looks generic or vibecoded, evaluate visual quality or polish, says "review this UI", "is this design good", "audit my frontend", "does this feel like [product]", "design QA", or when frontend-design routes here. Sub-skill of frontend-design.

日本語の概要は準備中です。原文の説明を表示しています。

Map symbol dependencies, callers, and blast radius before editing code. Load when the user asks what depends on a symbol, what breaks if they change something, blast radius of a change, reverse dependencies, or which tests cover a function. Also triggers on "who calls this", "impact of changing", "dependency map", "what uses this", "find callers", or before any non-trivial edit when safe-change is not yet active. Pairs with codebase-understanding for broad architecture; this skill is symbol-scoped and edit-gated.

日本語の概要は準備中です。原文の説明を表示しています。

Generate a single unified changelog from git history that works for everyone in the company (managers and non-tech colleagues as well as developers). Outputs Slack mrkdwn so it can be pasted straight into Slack. Defaults to Slovak (English only on explicit request) and to comparing the release branch (main) against develop to show unreleased changes; also supports date ranges like "today", "yesterday", "last week", or an explicit git range. User-invoked only via /changelog.

日本語の概要は準備中です。原文の説明を表示しています。

Automate Castingwords tasks via Rube MCP (Composio). Always search tools first for current schemas.

日本語の概要は準備中です。原文の説明を表示しています。

Automate Astica AI tasks via Rube MCP (Composio). Always search tools first for current schemas.

日本語の概要は準備中です。原文の説明を表示しています。

Security audit, hardening, threat modeling (STRIDE/PASTA), Red/Blue Team, OWASP checks, code review, incident response, and infrastructure security for any project.

日本語の概要は準備中です。原文の説明を表示しています。

Annotates bacterial and archaeal genomes (isolates, MAGs, plasmids) with Bakta (active versioned databases, NCBI-compliant output) or Prokka (legacy), producing GFF3/GenBank/EMBL/FASTA with INSDC locus tags. Covers Bakta-vs-Prokka-vs-PGAP-vs-DFAST choice, light-vs-full database tiers, translation-table selection (11/4/25), archaeal and leaderless-gene caveats, the small-ORF blind spot, pseudogene-vs-phase-variation, the pangenome re-annotation trap, and submission compliance. Use when annotating a newly assembled prokaryotic genome, choosing an annotation tool, re-annotating a collection for pangenomics, or preparing annotations for NCBI/DDBJ submission.

日本語の概要は準備中です。原文の説明を表示しています。

Estimates time-scaled phylogenies, molecular clock rates, effective reproduction number R_e (or R_t), and population dynamics from dated pathogen genomes using TreeTime (maximum-likelihood) and BEAST2 (Bayesian; strict / uncorrelated lognormal / ORC clocks; constant / exponential / Bayesian Skyline / Skygrid / BICEPS / Birth-Death-Skyline / sampled-ancestor BDSKY priors; structured coalescent via MASCOT). Covers root-to-tip clock signal QC via TempEst, date-randomisation tests (Ramsden 2009; Duchêne 2015), recombination masking via Gubbins and ClonalFrameML before clock inference for recombining bacteria, BDSKY origin-vs-rootHeight pitfalls, sampling-bias correction (Volz & Frost 2014; preferential-sampling extensions), MASCOT structured coalescent for migration, BICEPS-vs-BSP skyline choice, multi-chain BEAST2 convergence diagnostics, and reconciliation between phylodynamic R_e and case-based R_t. Use when dating outbreak origins, estimating substitution rates, inferring R_e through time, building time-calibrated Nextstrain Augur trees, choosing between strict and relaxed clocks, fitting Birth-Death-Skyline (Stadler 2013) models, diagnosing temporal-signal failure, masking recombination before clock inference for *Streptococcus pneumoniae* / *Neisseria gonorrhoeae* / *Klebsiella* / *E. coli* phylodynamics, running MASCOT for structured-population analyses, or using UShER for pandemic-scale placement.

日本語の概要は準備中です。原文の説明を表示しています。

Compute genome-to-genome distances (ANI, AAI, dDDH, k-mer Mash) and assign taxonomic classifications using skani (Shaw 2023), FastANI (Jain 2018), pyani / pyANI ANIb / ANIm, OrthoANI (Lee 2016), AAI (amino-acid identity), dDDH via TYGS / GGDC, GTDB-Tk (Chaumeil 2020 standard prokaryote taxonomy), and Mash MinHash (Ondov 2016). Use when delineating prokaryote species (95% ANI threshold; Jain 2018 Nat Commun 9:5114), assigning genomes to GTDB taxonomy with ANI radius, computing genome similarity matrices for clustering, classifying archaea, evaluating MAG (metagenome-assembled genome) species assignment, applying skani for fast metagenomic ANI screening, or reconciling 16S rRNA-based taxonomy with whole-genome ANI.

日本語の概要は準備中です。原文の説明を表示しています。

Designs adaptive clinical trials including group-sequential (O'Brien-Fleming, Pocock, Lan-DeMets spending), sample-size re-estimation (blinded Friede-Kieser, unblinded Cui-Hung-Wang, Mehta-Pocock promising zone), seamless Phase 2/3 with treatment-arm selection, population enrichment, and response-adaptive randomisation. Covers FDA 2019 Final Adaptive Designs Guidance, FDA 2022 Master Protocols, and ICH E20 Step 2b/3 draft (June 2025, NOT final). Use when planning interim analyses, sample-size re-estimation, or master/platform-trial designs.

日本語の概要は準備中です。原文の説明を表示しています。

Use this skill to determine whether you need interstate FMCSA authority or just intrastate state authority. Covers the federal/state divide.

日本語の概要は準備中です。原文の説明を表示しています。