「symmetry」の検索結果

游戏设计 (Game Design) — 设计游戏的规则 / 系统 / 机制 / 体验 的从业者认知操作系统 (以电子游戏为主, 含桌游 / 卡牌 / 棋盘游戏): 决定「玩家做什么、为什么有意义、每一刻的体验如何」的学科 —— 区别于游戏程序 (引擎 / 代码)、游戏美术 (视觉 / 音频)、游戏制作 (排期 / 预算 / 团队)。覆盖 (a) 核心设计理论与框架 (MDA 机制-动态-美学 Hunicke/LeBlanc/Zubek + Schell 的「透镜」+ Koster「乐趣即学习」理论 + Sid Meier「一连串有趣的决策」+ Salen & Zimmerman「有意义的游玩」/「二阶设计」/「魔法圈」+ Costikyan 论不确定性 + Suits/Huizinga 游戏哲学), (b) 系统与机制设计 (核心循环 + 游戏经济 sink/source/产出-消耗 + 正负反馈环 + 资源与成长系统 + 涌现 vs 脚本 Will Wright「可能性空间」+ Machinations 经济建模 Dormans + 支配 / 退化策略 + 正交设计 Garfield), (c) 关卡与遭遇设计 (灰盒 blockout + 节奏与张力 + 预告 telegraphing + 主线 vs 探索 + 环境叙事 + 锁钥 gating + 难度曲线), (d) 游戏手感与「juice」(Steve Swink《Game Feel》+ 即时响应 + 屏震 / 反馈 / 打磨 + 输入与镜头 + 「手感」是设计出来的不是附带的), (e) 玩家心理与 UX (Celia Hodent《The Gamer's Brain》+ 心流通道 挑战 vs 技能 Csikszentmihalyi/陈星汉 Jenova Chen + Bartle 玩家类型 + 动机与奖励节奏 + 新手引导 FTUE / 教学化 + 认知负荷 + 无障碍), (f) 平衡与调优 (Ian Schreiber《Game Balance》+ 对称 / 非对称 + 动态难度 DDA + 传递 / 非传递平衡 + nerf/buff + 消除支配策略 + 测试驱动调优), (g) 叙事与任务设计 (ludonarrative 失调 / 和谐 + 环境与系统叙事 + 分支 vs 线性 + Amy Hennig 角色驱动 + 任务结构), (h) 以玩家为中心的迭代流程 (Tracy Fullerton《Game Design Workshop》playcentric + 纸面原型 + 垂直切片 + 测试协议「看而不说 / 你不是你的玩家」+ 快速迭代 + game jam), (i) 类型与形态工艺 (roguelike/roguelite 与程序生成 Derek Yu + 平台跳跃 + RPG 系统 + 策略 4X + 解谜设计 Jonathan Blow + 多人 / PvP 平衡 + 桌游 / 卡牌设计 Reiner Knizia/Richard Garfield/Brenda Romero), (j) F2P / 长线运营 / 商业化设计 (核心 / 元 / 经济循环 + 抽卡 gacha / 开箱 loot box / 战令 battle pass 机制 + 留存 D1/D7/D30 + 转化 + 鲸鱼 + live ops 内容节奏 —— 并诚实处理掠夺式暗黑模式 / 强迫循环 / 剥削式商业化的伦理), (k) 设计师角色与工艺职业 (系统 / 关卡 / 叙事 / UX 设计师之分 + 通才 vs 专才 + 独立作者 vs 3A 团队 + 设计文档 + 传达设计意图 + GDC 工艺社区)。跨 3A / 独立 / 手游 F2P / 桌游。不含 游戏程序 / 引擎 (Unity/Unreal 编码 / 图形 / 网络同步) / 游戏美术 / 动画 / 音频 / 游戏制作 / 项目管理 / 排期 / QA / 游戏作为生意 / 发行 / 市场 / 电竞运营为终点 / 泛泛「我想做游戏」的 game-dev 教程 —— 本 skill 是「设计」学科: 规则 / 系统 / 机制 / 体验。 (Game Design — the cognitive operating system of practitioners who design the rules, systems, mechanics, and experiences of games (video games primarily, plus tabletop/board/card games): the discipline of deciding WHAT the player does, WHY it is meaningful, and HOW the moment-to-moment experience feels — distinct from game programming (builds the engine/code), game art (visuals/audio), and game production (schedule/budget/team). Covers (a) core design theory & frameworks (MDA Mechanics-Dynamics-Aesthetics Hunicke/LeBlanc/Zubek, Schell's Lenses, Koster's theory of fun = learning, Sid Meier 'a series of interesting decisions', Salen & Zimmerman 'meaningful play'/'second-order design'/'magic circle', Costikyan on uncertainty, Suits/Huizinga play philosophy), (b) systems & mechanics design (core loops, game economy sink/source/faucet-drain, feedback loops positive/negative, resource & progression systems, emergence vs scripting Will Wright 'possibility space', Machinations economy modeling Dormans, dominant/degenerate strategy, orthogonal design Garfield), (c) level & encounter design (blockout/greybox, pacing & tension, telegraphing, critical path vs exploration, environmental storytelling, gating & lock-and-key, difficulty curve), (d) game feel & juice (Steve Swink 'Game Feel', moment-to-moment responsiveness, screenshake/feedback/polish, input & camera, the 'feel' is designed not incidental), (e) player psychology & UX (Celia Hodent 'The Gamer's Brain', flow channel challenge-vs-skill Csikszentmihalyi/Jenova Chen, Bartle player types, motivation & reward schedules, onboarding/FTUE/tutorialization, cognitive load, accessibility), (f) balancing & tuning (Ian Schreiber 'Game Balance', symmetry/asymmetry, dynamic difficulty adjustment DDA, transitive/intransitive balance, nerf/buff, dominant strategy elimination, playtesting-driven tuning), (g) narrative & quest design (ludonarrative dissonance/harmony, environmental & systemic storytelling, branching vs linear, Amy Hennig character-driven, quest structure), (h) player-centric iterative process (Tracy Fullerton 'Game Design Workshop' playcentric design, paper prototyping, vertical slice, playtesting protocol 'watch don't talk / you are not your play

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Deep symmetries and unifying principles — gauge theory, Lie groups, Noether's theorem, and the Standard Model. Constructs field theories from symmetry requirements, derives conservation laws, and traces force unification. Use when working with gauge symmetry, Lie groups (U(1), SU(2), SU(3)), conservation laws via Noether's theorem, the Higgs mechanism, or Standard Model structure.

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Design small interfering RNA and antisense oligonucleotide sequences against a transcript, and screen them for the failure modes specific to nucleic-acid drugs. Use this skill to tile a target transcript, apply positional and thermodynamic selection rules including duplex asymmetry and nearest-neighbour melting temperature, scan candidates for seed-region complementarity to off-target transcripts, and lay out a chemical modification pattern — gapmer architecture, 2'-O-methyl and 2'-MOE wings, locked nucleic acid, and phosphorothioate placement. Also trigger on siRNA, antisense oligonucleotide, ASO, gapmer, RNase H, seed region, duplex asymmetry, 2'-MOE, locked nucleic acid, phosphorothioate, or GalNAc conjugate.

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Analyzes, validates, converts, and transforms materials structures and computed materials data with pymatgen. Use for local phase diagrams, symmetry sensitivity, electronic-structure I/O, and bounded Materials Project queries.

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Polish and refine existing motion against the transitions.dev motion-token scale — duration, distance, scale, blur, and easing — plus the rules for WHEN each token applies (open/close asymmetry, hover-in vs hover-out, stagger offsets, and intent delays). An add-on to the transitions-dev skill, focused on tuning what already animates rather than adding new transitions. Use when the user asks to "polish my transitions", "refine the motion", "tune the timing / easing", "make the animation feel better / less janky", "tighten the durations", "fix the stagger", "align to the motion tokens", "audit the motion", "review my animations", "scan for ad-hoc transitions", "tokenize my animations", or runs the commands transitions review or transitions polish. Also drives the Refine panel's Small refinement feature. Triggers on "motion polish", "transition polish", "refine motion", "timing feels off", "too slow / too fast", "stagger", "delay", "open close timing", "hover in out".

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Use when the mechanism analysis for a 《会计研究》 (Accounting Research) manuscript is missing or mis-specified — the channel must be an information mechanism (reduce information asymmetry, raise disclosure quality, constrain earnings management, improve audit assurance), not a generic pricing or financing channel. Use after the main result holds.

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Predict peptide-MHC class II (HLA-DR/DQ/DP) binding and presentation for CD4 T-cell epitopes with NetMHCIIpan-4.3 and MixMHC2pred-2.0. Covers why class II is far less reliable than class I (open binding groove, 9-mer register ambiguity, sparse noisy training data, DR>DP>DQ accuracy asymmetry), the DQ/DP heterodimer alpha/beta pairing trap, and the looser 1%/5% %Rank thresholds. Use when predicting CD4 epitopes for vaccine help, mapping class II neoantigens, or scoring long peptides against DR/DQ/DP. For CD8/class I see mhc-binding-prediction.

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Performs set operations on genomic intervals - intersect (-wa/-wb/-wo/-wao/-loj/-c/-v/-u), subtract (-A), merge (-d, -c/-o), complement, cluster, multiinter, unionbedg, map, and groupby - with bedtools (CLI) and pybedtools/pyranges/bioframe (Python). Covers the sorted-input contract and the -sorted chromosome-order footgun, reciprocal/fractional overlap (-f/-F/-r/-e) and the A-vs-B asymmetry, -split for spliced/BED12/BAM features, and jaccard/fisher as mechanics only. Use when finding overlapping or unique regions between BED/peak/feature files, building consensus peaksets, removing blacklisted regions, transferring annotation values onto intervals, or computing interval-set similarity; route overlap-significance testing to overlap-significance.

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Predict B-cell and T-cell epitopes for vaccine antigen design and epitope mapping with BepiPred-3.0, DiscoTope-3.0, the IEDB tools, and EL-mode MHC presentation. Encodes the load-bearing asymmetry that T-cell epitope prediction is mature (it reduces to MHC presentation, AUC>0.9) while B-cell prediction is unreliable (linear predictors ~AUC 0.6 because ~90% of real epitopes are conformational) — so structure-based DiscoTope-3.0 on AlphaFold models is the only defensible B-cell path, propensity scales are obsolete, and NetChop is largely redundant on EL-trained models. Use when mapping epitopes or selecting vaccine antigens. MHC binding lives in mhc-binding-prediction.

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Designs donor/repair templates for precise CRISPR knock-ins -- choosing the format (ssODN, long-ssDNA/Easi-CRISPR, dsDNA/plasmid, AAV6), sizing homology arms, placing the cut within ~10 bp of the edit, and adding a mandatory codon-checked blocking (PAM/seed) mutation so the edited allele is not re-cut. Frames the HDR-vs-NHEJ-vs-MMEJ pathway competition, the MMEJ (PITCh) and homology-independent (HITI/HMEJ) alternatives for post-mitotic cells, ssODN strand/asymmetry choice, phosphorothioate end-protection, and ranked HDR enhancers. Use when designing a donor for a point mutation, epitope/fluorophore tag, allele replacement, or knock-in, or when HDR efficiency is low. Guide design and base/prime editing are separate skills.

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Build forest plots (HR, OR, RR, beta-coefficient summaries with CIs) and funnel plots (meta-analysis publication-bias diagnostics) using forestplot, metafor, ggforest, and MendelianRandomization with proper axis-scaling, summary-diamond placement, subgroup nesting, and Egger / trim-and-fill asymmetry tests. Use when summarizing effects across subgroups, trials, or instruments — meta-analysis, Mendelian randomization, subgroup HRs.

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Evaluate completed mediation-competition problems consisting of general information and confidential packets for both sides. Use when asked to validate, audit, score, quality-control, or assess competition readiness; identify factual, numerical, chronological, authority, commercial-logic, or confidentiality defects; test mediation usefulness, BATNAs, settlement corridors, information asymmetry, and opportunities for firmness, cooperation, imagination, and clarification; or produce an author-only validation report. Perform a qualified partial review when packets are missing. Diagnose by default; do not generate a new problem or edit source packets unless repairs are expressly requested. Requires access to all supplied files and a host capable of reading their formats; otherwise disclose the unreviewed material and resulting limits.

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Create original, competition-ready commercial mediation problems and confidential packets with iterative validation. Use when a user provides a topic, industry, dispute sketch, or existing general-information packet and wants a public packet plus confidential packets for both sides—or one named side. Build a narrow but workable settlement corridor; verify factual and numerical consistency, information asymmetry, balance, originality, and commercial feasibility; and revise until deterministic and semantic exit criteria pass. Do not use merely to summarize an existing packet or to advise parties in a real dispute. Requires local file access; Python 3 is recommended for bundled deterministic checks, with disclosed manual fallbacks when unavailable.

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Enforce existence, reuse, mirror, and symmetry principles to keep new code minimal and consistent with surrounding code. Use when writing new code in an existing codebase, adding new features, refactoring, or making any code changes.

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Investment Thesis Generator — builds a complete, structured investment thesis with bull/bear cases, catalyst timeline, entry/exit strategies, position sizing, and asymmetry assessment for any publicly traded stock.

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Automatically identify metamorphic properties (symmetry, linearity, additivity, input invariances) from programs or functions. Use when generating metamorphic tests, discovering program properties, validating transformations, or creating test oracles without explicit specifications. Analyzes control flow, data flow, and sample executions to output structured properties for metamorphic test generation and verification.

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Think and work like an expert Crystallographer. Use when a task calls for Crystallographer judgment. Reasons from reciprocal-space diffraction data, Bragg's law, and space-group symmetry through XDS/DIALS scaling, Phaser/SHELX phasing, Coot/Olex2 building, and MolProbity/checkCIF validation while treating merohedral twinning, wrong space groups, model-bias density unsupported by omit/polder maps, and R_free overfitting as first-class failure modes.

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Think and work like an expert Condensed Matter Physicist. Use when a task calls for Condensed Matter Physicist judgment. Reasons from Bloch bands, quasiparticles, and symmetry through ARPES/STM/neutron/transport workflows, VASP/QE/Wannier90/DMFT, and Materials Project/ICSD/MPDS while treating matrix-element artifacts, Mott vs. DFT gaps, pseudogap vs. SC gap, and Planckian bad-metal transport as first-class failure modes.

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Build forest plots (HR, OR, RR, beta-coefficient summaries with CIs) and funnel plots (meta-analysis publication-bias diagnostics) using forestplot, metafor, ggforest, and MendelianRandomization with proper axis-scaling, summary-diamond placement, subgroup nesting, and Egger / trim-and-fill asymmetry tests. Use when summarizing effects across subgroups, trials, or instruments — meta-analysis, Mendelian randomization, subgroup HRs.

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Operates or audits a live Qualtrics survey through the v3 APIs without disrupting fielding. Covers publish gating, quotas, flow routing, embedded data, panel-vendor redirects, read-back verification, and a read-only pre-fielding audit. Use when publishing or patching a fielding instrument, when a quota counts without blocking, when configuring panel-vendor redirects or flow gates, or when auditing a survey before launch for consent gates, force-response completeness, quotas and redirects, anti-bot instrumentation, and language-arm symmetry.

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Evaluates market structure dynamics with order book analysis, spread decomposition, and information asymmetry assessment. Use when analyzing market structure, evaluating trading venues, or assessing execution quality.

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Systematically interpret Raman spectra to identify molecular vibrations, assess polarizability-driven selection rules, compare with complementary IR data, and evaluate depolarization ratios for symmetry assignment. Covers Raman-active mode identification, fluorescence interference mitigation, and reference spectrum matching.

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Calculate and visualize magnetic fields produced by current distributions using the Biot-Savart law, Ampere's law, and magnetic dipole approximations. Use when computing B-fields from arbitrary current geometries, exploiting symmetry with Ampere's law, analyzing superposition of multiple sources, or characterizing magnetic materials through permeability, B-H curves, and hysteresis behavior.

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Investment Thesis Generator — complete institutional-quality thesis with bull/bear cases (3-5 reasons each with evidence), catalyst timeline, entry/exit strategy with specific price levels, position sizing tables, timeframe classification, and asymmetry assessment. Triggered by "trade thesis <TICKER>".

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