「trimming」の検索結果

Guidelines for making .NET libraries and applications trimming-safe and Native AOT compatible. Covers the trimming/AOT model, the MSBuild properties that enable analysis (IsTrimmable, IsAotCompatible, PublishTrimmed, PublishAot), the trimming attributes (RequiresUnreferencedCode, RequiresDynamicCode, DynamicallyAccessedMembers, UnconditionalSuppressMessage), IL2xxx/IL3xxx warning codes, and a pattern playbook: source generators and UnsafeAccessor, generated-interception diagnostic suppressors, intentional runtime scanning boundaries, trimming-safe islands and feature switches, migration analyzers, and temporary warning-approval baselines. Use when introducing trimming/AOT support, resolving IL2xxx/IL3xxx warnings, or making reflection-heavy code trimming-safe in C# / .NET codebases. For System.Text.Json AOT scenarios, see also the serialization skill.

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Make .NET projects compatible with Native AOT and trimming by systematically resolving IL trim/AOT analyzer warnings. USE FOR: making projects AOT-compatible, fixing trimming warnings, resolving IL warnings (IL2026, IL2070, IL2067, IL2072, IL3050), adding DynamicallyAccessedMembers annotations, enabling IsAotCompatible. DO NOT USE FOR: publishing native AOT binaries, optimizing binary size, replacing reflection-heavy libraries with alternatives. INVOKES: no tools — pure knowledge skill.

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Preprocess CLIP-seq reads (eCLIP, iCLIP, iCLIP2, iCLIP3, irCLIP, PAR-CLIP, FLASH) with protocol-specific UMI extraction, adapter trimming, length filtering, and post-alignment PCR-duplicate collapse. Use when raw CLIP FASTQ must be turned into deduplicated, crosslink-preserving BAM input for peak calling; choosing between two-pass and single-pass adapter trimming; deciding minimum read length; or mapping UMI patterns to specific eCLIP/iCLIP/iCLIP2/iCLIP3 library preps.

日本語の概要は準備中です。原文の説明を表示しています。

Make .NET projects compatible with Native AOT and trimming by systematically resolving IL trim/AOT analyzer warnings. USE FOR: making projects AOT-compatible, fixing trimming warnings, resolving IL warnings (IL2026, IL2070, IL2067, IL2072, IL3050), adding DynamicallyAccessedMembers annotations, enabling IsAotCompatible. DO NOT USE FOR: publishing native AOT binaries, optimizing binary size, replacing reflection-heavy libraries with alternatives. INVOKES: no tools — pure knowledge skill.

日本語の概要は準備中です。原文の説明を表示しています。

Preprocess CLIP-seq reads (eCLIP, iCLIP, iCLIP2, iCLIP3, irCLIP, PAR-CLIP, FLASH) with protocol-specific UMI extraction, adapter trimming, length filtering, and post-alignment PCR-duplicate collapse. Use when raw CLIP FASTQ must be turned into deduplicated, crosslink-preserving BAM input for peak calling; choosing between two-pass and single-pass adapter trimming; deciding minimum read length; or mapping UMI patterns to specific eCLIP/iCLIP/iCLIP2/iCLIP3 library preps.

日本語の概要は準備中です。原文の説明を表示しています。

Preprocess CLIP-seq reads (eCLIP, iCLIP, iCLIP2, iCLIP3, irCLIP, PAR-CLIP, FLASH) with protocol-specific UMI extraction, adapter trimming, length filtering, and post-alignment PCR-duplicate collapse. Use when raw CLIP FASTQ must be turned into deduplicated, crosslink-preserving BAM input for peak calling; choosing between two-pass and single-pass adapter trimming; deciding minimum read length; or mapping UMI patterns to specific eCLIP/iCLIP/iCLIP2/iCLIP3 library preps.

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SoX（Sound eXchange）を使用した音声処理の専門スキル。音声ファイルの変換、編集、エフェクト適用を効率的に支援。フォーマット変換（WAV/MP3/FLAC/OGG/AIFF等）、音声編集（トリム、結合、分割、フェード）、エフェクト（ノイズ除去、ノーマライズ、EQ、リバーブ、コンプレッサー）、分析（soxi、stat、spectrogram）など幅広い操作をカバー。Use when converting audio formats, applying audio effects, trimming/splitting audio files, normalizing volume, removing noise, generating spectrograms, or processing audio for podcasts/music production.

FFmpegを使用したマルチメディア処理の専門スキル。動画・音声の変換、編集、最適化を効率的に支援。フォーマット変換、コーデック選択、フィルタ適用、ストリーミング準備、ハードウェアアクセラレーションなど幅広い操作をカバー。Use when converting video/audio formats, transcoding codecs, trimming/cutting media, creating GIFs, extracting audio, adding watermarks, preparing for streaming (HLS/DASH), or optimizing media files for web/mobile.

Make .NET projects compatible with Native AOT and trimming by systematically resolving IL trim/AOT analyzer warnings. USE FOR: making projects AOT-compatible, fixing trimming warnings, resolving IL warnings (IL2026, IL2070, IL2067, IL2072, IL3050), adding DynamicallyAccessedMembers annotations, enabling IsAotCompatible. DO NOT USE FOR: publishing native AOT binaries, optimizing binary size, replacing reflection-heavy libraries with alternatives. INVOKES: no tools — pure knowledge skill.

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Windows アプリ開発 (Win32 / WPF / WinForms 相互運用) の相互運用・近代化リファレンス。 Win32 API, CreateWindowExW, WNDPROC, メッセージループ, COM (IUnknown, CoCreateInstance, ComPtr), CsWin32, windows-rs, C++/WinRT (winrt::com_ptr, IAsyncOperation, IDL, ABI 相互運用), C#/WinRT (cswinrt, ComWrappers, AOT/trimming, WindowNative), XAML Islands (DesktopWindowXamlSource, DesktopChildSiteBridge, WindowsXamlManager), WPF/WinForms 相互運用 (HwndHost, HwndSource, WindowsFormsHost, ElementHost), UWP から Windows App SDK / WinUI 3 への 移行 (namespace mapping, AppWindow, DispatcherQueue, .NET Upgrade Assistant)。

Preprocess CLIP-seq reads (eCLIP, iCLIP, iCLIP2, iCLIP3, irCLIP, PAR-CLIP, FLASH) with protocol-specific UMI extraction, adapter trimming, length filtering, and post-alignment PCR-duplicate collapse. Use when raw CLIP FASTQ must be turned into deduplicated, crosslink-preserving BAM input for peak calling; choosing between two-pass and single-pass adapter trimming; deciding minimum read length; or mapping UMI patterns to specific eCLIP/iCLIP/iCLIP2/iCLIP3 library preps.

日本語の概要は準備中です。原文の説明を表示しています。

Preprocess CLIP-seq reads (eCLIP, iCLIP, iCLIP2, iCLIP3, irCLIP, PAR-CLIP, FLASH) with protocol-specific UMI extraction, adapter trimming, length filtering, and post-alignment PCR-duplicate collapse. Use when raw CLIP FASTQ must be turned into deduplicated, crosslink-preserving BAM input for peak calling; choosing between two-pass and single-pass adapter trimming; deciding minimum read length; or mapping UMI patterns to specific eCLIP/iCLIP/iCLIP2/iCLIP3 library preps.

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Edit videos locally using ffmpeg. Trim, concat, resize, speed, overlay, extract audio, compress, and convert. Use when: (1) Trimming or cutting video segments, (2) Concatenating multiple clips, (3) Resizing video for social platforms, (4) Extracting or replacing audio, (5) Compressing video, (6) Converting video formats, (7) Getting video info.

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Processes paired-end 16S amplicon reads into QIIME 2 ASVs and taxonomy with retained artifact provenance. Checks paired FASTQ manifests, primer orientation diagnostics, predicted post-trimming overlap, sample IDs, runtime versions and read retention, and guides selection of compatible taxonomic classifiers.

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Converts genomic intervals between coordinate conventions, normalises and compares variant representations, and detects assembly or contig-naming mismatches before they corrupt an analysis. Used whenever coordinates cross a format, tool, or assembly boundary - converting between BED, GFF/GTF, VCF, SAM/BAM, WIG, PSL, genePred, Picard interval_list, or region strings; reconciling 0-based half-open with 1-based inclusive; left-aligning or trimming indels; checking whether two variant records describe the same change; mapping genomic to transcript, CDS, or protein positions; auditing a BED/GTF/VCF for convention violations; or diagnosing GRCh37 vs hg19 vs GRCh38 vs T2T, chr-prefix, and liftover problems. Triggers include "off by one", "0-based", "1-based", "half-open", "coordinate system", "left-align", "normalize variant", "bcftools norm", "chr prefix", "wrong genome build", "liftover", "REF mismatch", and "HGVS".

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Optimize the description prompts an AI agent reads to learn its built-in tools (the `.md` files under prompts/tools/). Two halves: (1) measure how much of a prompt is already inferable from the tool's JSON parameter schema + name, to prune redundancy with evidence; (2) house authoring rules for what belongs in a tool prompt vs what stays in code. Use when auditing, trimming, writing, or reviewing tool prompts, deciding what schema field descriptions already cover, or testing schema-vs-prompt overlap before deleting prompt lines.

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Strategies for managing LLM context windows including summarization, trimming, routing, and avoiding context rot Use when: context window, token limit, context management, context engineering, long context.

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Reduces an always-on LifeOS context file that has grown too big via a human-gated pass — deterministic GC of stale entries first, then semantic merges and relocations — never dropping a directive and committing every change reversibly. USE WHEN /trim, trim the context, trim OPERATIONAL_RULES, this file is too big, reduce a doctrine file, prune an always-loaded file, fold the proposal inbox, shrink CLAUDE.md or DA_IDENTITY. NOT FOR general code refactoring, trimming video or audio media (use AudioEditor for audio files), or removing AI writing patterns from prose.

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Validate FASTQ inputs, run local FastQC/MultiQC QC, interpret QC signals, and optionally execute fastp or Cutadapt trimming branches without overwriting raw reads.

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Establish MSBuild/.NET build performance baselines before optimizing. USE FOR: a .NET build or solution that is slow or has build-performance concerns; cold, warm, incremental, or no-op measurements; before/after comparisons; CI build output caching; static graph build decisions; artifacts output; and dependency graph trimming. Start here before build-perf-diagnostics, incremental-build, or build-parallelism. DO NOT USE for webpack, npm, JavaScript bundlers, or other non-MSBuild build systems. For detailed target/task/analyzer bottleneck analysis after baselining, use build-perf-diagnostics.

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Remove sequencing adapters from FASTQ files using Cutadapt and Trimmomatic. Supports single-end and paired-end reads, Illumina TruSeq, Nextera, and custom adapter sequences. Use when FastQC shows adapter contamination or before alignment of short reads.

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Filter reads by quality scores, length, and N content using Trimmomatic and fastp. Apply sliding window trimming, remove low-quality bases from read ends, and discard reads below thresholds. Use when reads have poor quality tails or require minimum quality for downstream analysis.

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Preprocess ribosome profiling data including adapter trimming, size selection, rRNA removal, and alignment. Use when preparing Ribo-seq reads for downstream analysis of translation.

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All-in-one read preprocessing with fastp including adapter trimming, quality filtering, deduplication, base correction, and HTML report generation. Use when preprocessing Illumina data and wanting a single fast tool instead of separate Cutadapt, Trimmomatic, and FastQC steps.

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