AI-powered adeno-associated virus (AAV) vector design for gene therapy including capsid engineering, promoter selection, and tropism optimization.
日本語の概要は準備中です。原文の説明を表示しています。
Apply modern web development best practices for security, compatibility, and code quality. Use when asked to "apply best practices", "security audit", "modernize code", "code quality review", or "check for vulnerabilities".
インストールする前に、エージェントに与えられる指示の中身を確認できます。
Modern web development standards based on Lighthouse best practices audits. Covers security, browser compatibility, and code quality patterns.
Enforce HTTPS:
<!-- ❌ Mixed content -->
<img src="http://example.com/image.jpg">
<script src="http://cdn.example.com/script.js"></script>
<!-- ✅ HTTPS only -->
<img src="https://example.com/image.jpg">
<script src="https://cdn.example.com/script.js"></script>
Avoid protocol-relative URLs (//example.com/...) — they're an HTTP-era pattern with no benefit on HTTPS-only sites and hide the actual scheme from reviewers.
HSTS Header:
Strict-Transport-Security: max-age=31536000; includeSubDomains; preload
<!-- Basic CSP via meta tag -->
<meta http-equiv="Content-Security-Policy"
content="default-src 'self';
script-src 'self' https://trusted-cdn.com;
style-src 'self' 'unsafe-inline';
img-src 'self' data: https:;
connect-src 'self' https://api.example.com;">
<!-- Better: HTTP header -->
CSP Header (recommended):
Content-Security-Policy:
default-src 'self';
script-src 'self' 'nonce-abc123' https://trusted.com;
style-src 'self' 'nonce-abc123';
img-src 'self' data: https:;
connect-src 'self' https://api.example.com;
frame-ancestors 'self';
base-uri 'self';
form-action 'self';
Using nonces for inline scripts:
<script nonce="abc123">
// This inline script is allowed
</script>
A strict CSP blocks loading untrusted script files, but it doesn't stop a string from reaching innerHTML, eval, or other DOM-XSS sinks. Trusted Types — Baseline across all major browsers since early 2026 — closes that hole by making sinks reject raw strings and accept only typed objects produced by a named policy.
Content-Security-Policy: require-trusted-types-for 'script'; trusted-types default;
// One central policy that does the sanitization
const escape = trustedTypes.createPolicy('default', {
createHTML: (s) => DOMPurify.sanitize(s, { RETURN_TRUSTED_TYPE: true })
});
// ❌ This now throws TypeError under enforcement
element.innerHTML = userInput;
// ✅ Goes through the policy
element.innerHTML = escape.createHTML(userInput);
Roll out with Content-Security-Policy-Report-Only first to find every sink usage in your app, then flip to enforcement. Angular has built-in Trusted Types support; React 19+ produces TrustedHTML when Trusted Types are enforced; for everything else, DOMPurify is the de-facto sanitizer.
Pin every <script> and <link rel="stylesheet"> you load from a CDN you don't control. If the CDN is compromised — as happened to polyfill.io in 2024 — the browser refuses to execute a file whose hash doesn't match.
<script src="https://cdn.example.com/lib@1.2.3/dist/lib.js"
integrity="sha384-oqVuAfXRKap7fdgcCY5uykM6+R9GqQ8K/uxy9rx7HNQlGYl1kPzQho1wx4JwY8wC"
crossorigin="anonymous"></script>
integrity accepts space-separated hashes; include the next version's hash before rotating to avoid downtime. Generate with openssl dgst -sha384 -binary file.js | openssl base64 -A. SRI requires crossorigin and an Access-Control-Allow-Origin response header from the CDN.
# Prevent clickjacking — prefer CSP `frame-ancestors` (above); X-Frame-Options
# is the legacy fallback for older browsers.
X-Frame-Options: DENY
# Prevent MIME type sniffing
X-Content-Type-Options: nosniff
# Do NOT send X-XSS-Protection. The legacy browser XSS auditor was deprecated
# and removed (Chrome 78, Edge 17), and in some cases it introduced its own
# vulnerabilities. Use a strict CSP + Trusted Types (below) instead.
# Control referrer information
Referrer-Policy: strict-origin-when-cross-origin
# Permissions policy (formerly Feature-Policy)
Permissions-Policy: geolocation=(), microphone=(), camera=()
# Check for vulnerabilities
npm audit
yarn audit
# Auto-fix when possible
npm audit fix
# Check specific package
npm ls lodash
Keep dependencies updated:
// package.json
{
"scripts": {
"audit": "npm audit --audit-level=moderate",
"update": "npm update && npm audit fix"
}
}
Known vulnerable patterns to avoid:
// ❌ Recursive merges of untrusted input can pollute Object.prototype
// via __proto__, constructor, or prototype keys.
_.merge(target, userInput); // lodash <4.17.20
$.extend(true, {}, target, userInput); // jQuery deep extend
Object.assign(target, ...userInputs); // safe by itself (shallow), but unsafe
// when target IS Object.prototype-derived
// and userInput contains __proto__
// ✅ For untrusted bags, use a null-prototype object so __proto__ is just a key
const safe = Object.create(null);
Object.assign(safe, userInput); // shallow, no recursion → safe by construction
// ✅ For deep copies, structuredClone drops __proto__ and functions
const deepSafe = structuredClone(userInput);
// ✅ For deep merges, use a library that explicitly blocks dangerous keys
// (e.g. lodash ≥4.17.21 _.mergeWith with a customizer, or deepmerge-ts).
// ❌ XSS vulnerable
element.innerHTML = userInput;
document.write(userInput);
// ✅ Safe text content
element.textContent = userInput;
// ✅ If HTML needed, sanitize
import DOMPurify from 'dompurify';
element.innerHTML = DOMPurify.sanitize(userInput);
// ❌ Insecure cookie
document.cookie = "session=abc123";
// ✅ Secure cookie (server-side)
Set-Cookie: session=abc123; Secure; HttpOnly; SameSite=Strict; Path=/
<!-- ❌ Missing or invalid doctype -->
<HTML>
<!DOCTYPE html PUBLIC "-//W3C//DTD HTML 4.01//EN">
<!-- ✅ HTML5 doctype -->
<!DOCTYPE html>
<html lang="en">
<!-- ❌ Missing or late charset -->
<html>
<head>
<title>Page</title>
<meta charset="UTF-8">
</head>
<!-- ✅ Charset as first element in head -->
<html>
<head>
<meta charset="UTF-8">
<title>Page</title>
</head>
<!-- ❌ Missing viewport -->
<head>
<title>Page</title>
</head>
<!-- ✅ Responsive viewport -->
<head>
<meta charset="UTF-8">
<meta name="viewport" content="width=device-width, initial-scale=1">
<title>Page</title>
</head>
// ❌ Browser detection (brittle)
if (navigator.userAgent.includes('Chrome')) {
// Chrome-specific code
}
// ✅ Feature detection
if ('IntersectionObserver' in window) {
// Use IntersectionObserver
} else {
// Fallback
}
// ✅ Using @supports in CSS
@supports (display: grid) {
.container {
display: grid;
}
}
@supports not (display: grid) {
.container {
display: flex;
}
}
Prefer bundling polyfills at build time (Babel/SWC + core-js, or @vitejs/plugin-legacy) targeted by your supported-browsers list. This eliminates the runtime check entirely and avoids shipping polyfill bytes to modern browsers.
If you must load a polyfill at runtime, append a script element — never use document.write (it blocks the parser and is broken in async/deferred contexts):
<script>
if (!('fetch' in window)) {
const s = document.createElement('script');
s.src = '/polyfills/fetch.js';
s.defer = true;
document.head.appendChild(s);
}
</script>
Never load polyfills from a third-party CDN you don't control. The polyfill.io service was compromised in mid-2024 in a supply-chain attack and used to serve malware to ~100k sites. Self-host, or use a vetted mirror (e.g. Cloudflare's cdnjs polyfill build) — and pin the version with Subresource Integrity.
// ❌ document.write (blocks parsing)
document.write('<script src="..."></script>');
// ✅ Dynamic script loading
const script = document.createElement('script');
script.src = '...';
document.head.appendChild(script);
// ❌ Synchronous XHR (blocks main thread)
const xhr = new XMLHttpRequest();
xhr.open('GET', url, false); // false = synchronous
// ✅ Async fetch
const response = await fetch(url);
// ❌ Application Cache (deprecated)
<html manifest="cache.manifest">
// ✅ Service Workers
if ('serviceWorker' in navigator) {
navigator.serviceWorker.register('/sw.js');
}
// ❌ Non-passive touch/wheel (may block scrolling)
element.addEventListener('touchstart', handler);
element.addEventListener('wheel', handler);
// ✅ Passive listeners (allows smooth scrolling)
element.addEventListener('touchstart', handler, { passive: true });
element.addEventListener('wheel', handler, { passive: true });
// ✅ If you need preventDefault, be explicit
element.addEventListener('touchstart', handler, { passive: false });
// ❌ Errors in production
console.log('Debug info'); // Remove in production
throw new Error('Unhandled'); // Catch all errors
// ✅ Proper error handling
try {
riskyOperation();
} catch (error) {
// Log to error tracking service
errorTracker.captureException(error);
// Show user-friendly message
showErrorMessage('Something went wrong. Please try again.');
}
class ErrorBoundary extends React.Component {
state = { hasError: false };
static getDerivedStateFromError(error) {
return { hasError: true };
}
componentDidCatch(error, info) {
errorTracker.captureException(error, { extra: info });
}
render() {
if (this.state.hasError) {
return <FallbackUI />;
}
return this.props.children;
}
}
// Usage
<ErrorBoundary>
<App />
</ErrorBoundary>
// Catch unhandled errors
window.addEventListener('error', (event) => {
errorTracker.captureException(event.error);
});
// Catch unhandled promise rejections
window.addEventListener('unhandledrejection', (event) => {
errorTracker.captureException(event.reason);
});
// ❌ Source maps exposed in production
// webpack.config.js
module.exports = {
devtool: 'source-map', // Exposes source code
};
// ✅ Hidden source maps (uploaded to error tracker)
module.exports = {
devtool: 'hidden-source-map',
};
// ✅ Or no source maps in production
module.exports = {
devtool: process.env.NODE_ENV === 'production' ? false : 'source-map',
};
Strip sourcesContent from production maps when uploading to your error tracker. By default, bundlers embed the full original source inside the .map file — anyone who obtains the map (including via a misconfigured upload step) gets your unminified code. Configure your bundler to omit sourcesContent, or use a Sentry/Bugsnag CLI flag that does so when uploading.
For Vite, prefer sourcemap: 'hidden' over 'true' so the //# sourceMappingURL= comment isn't emitted into the bundle.
// ❌ Blocking script
<script src="heavy-library.js"></script>
// ✅ Deferred script
<script defer src="heavy-library.js"></script>
// ❌ Blocking CSS import
@import url('other-styles.css');
// ✅ Link tags (parallel loading)
<link rel="stylesheet" href="styles.css">
<link rel="stylesheet" href="other-styles.css">
// ❌ Handler on every element
items.forEach(item => {
item.addEventListener('click', handleClick);
});
// ✅ Event delegation
container.addEventListener('click', (e) => {
if (e.target.matches('.item')) {
handleClick(e);
}
});
// ❌ Memory leak (never removed)
const handler = () => { /* ... */ };
window.addEventListener('resize', handler);
// ✅ Cleanup when done
const handler = () => { /* ... */ };
window.addEventListener('resize', handler);
// Later, when component unmounts:
window.removeEventListener('resize', handler);
// ✅ Using AbortController
const controller = new AbortController();
window.addEventListener('resize', handler, { signal: controller.signal });
// Cleanup:
controller.abort();
<!-- ❌ Invalid HTML -->
<div id="header">
<div id="header"> <!-- Duplicate ID -->
<ul>
<div>Item</div> <!-- Invalid child -->
</ul>
<a href="/"><button>Click</button></a> <!-- Invalid nesting -->
<!-- ✅ Valid HTML -->
<header id="site-header">
</header>
<ul>
<li>Item</li>
</ul>
<a href="/" class="button">Click</a>
<!-- ❌ Non-semantic -->
<div class="header">
<div class="nav">
<div class="nav-item">Home</div>
</div>
</div>
<div class="main">
<div class="article">
<div class="title">Headline</div>
</div>
</div>
<!-- ✅ Semantic HTML5 -->
<header>
<nav>
<a href="/">Home</a>
</nav>
</header>
<main>
<article>
<h1>Headline</h1>
</article>
</main>
<!-- ❌ Distorted images -->
<img src="photo.jpg" width="300" height="100">
<!-- If actual ratio is 4:3, this squishes the image -->
<!-- ✅ Preserve aspect ratio -->
<img src="photo.jpg" width="300" height="225">
<!-- Actual 4:3 dimensions -->
<!-- ✅ CSS object-fit for flexibility -->
<img src="photo.jpg" style="width: 300px; height: 200px; object-fit: cover;">
// ❌ Request on page load (bad UX, often denied)
navigator.geolocation.getCurrentPosition(success, error);
// ✅ Request in context, after user action
findNearbyButton.addEventListener('click', async () => {
// Explain why you need it
if (await showPermissionExplanation()) {
navigator.geolocation.getCurrentPosition(success, error);
}
});
<!-- Restrict powerful features -->
<meta http-equiv="Permissions-Policy"
content="geolocation=(), camera=(), microphone=()">
<!-- Or allow for specific origins -->
<meta http-equiv="Permissions-Policy"
content="geolocation=(self 'https://maps.example.com')">
npm audit)frame-ancestors, base-uri, form-action)require-trusted-types-for 'script' enforced (or report-only during rollout)<script>/<link rel="stylesheet"> pinned with SRI hashessourcesContent stripped from uploaded ones)| Tool | Purpose |
|---|---|
npm audit | Dependency vulnerabilities |
| SecurityHeaders.com | Header analysis |
| W3C Validator | HTML validation |
| Lighthouse | Best practices audit |
| Observatory | Security scan |
This skill is written to stay usable across GitHub Copilot, Claude Code, and Codex.
$CODEX_HOME/skills/best-practices and restart Codex after major changes.Preferred MCP Server: None required
best-practices outside its documented task boundary.Before claiming the best-practices workflow succeeded:
まだレビューはありません。使ってみた感想をお寄せください。
概要と使いどころ
AI-powered adeno-associated virus (AAV) vector design for gene therapy including capsid engineering, promoter selection, and tropism optimization.
日本語の概要は準備中です。原文の説明を表示しています。
Improve the clarity and voice of AI-assisted academic writing (papers, theses, rebuttals) and
日本語の概要は準備中です。原文の説明を表示しています。
12-agent academic paper writing pipeline. 11 modes (full/plan/outline/revision/revision-coach/abstract/lit-review/format-convert/citation-check/disclosure/rebuttal-audit). 6 paper types, 5 citation formats, bilingual abstracts, LaTeX/DOCX-via-Pandoc/PDF output. Style Calibration + Writing Quality Check + Anti-Patterns with IRON RULE markers. Triggers: write paper, academic paper, guide my paper, parse reviews, audit my rebuttal, check my response draft, AI disclosure, 寫論文, 學術論文, 引導我寫論文, 審查意見, 評估回覆, 논문 작성, 초록 작성, 논문 수정, 논문 계획을 도와줘, 심사 의견 반영, 답변서 점검, AI 사용 고지.
日本語の概要は準備中です。原文の説明を表示しています。
Systematic writing framework for philosophy and interdisciplinary academic papers from optimized outline to submission-ready manuscript. Use when users want to: (1) write a paper from a detailed outline, (2) ensure quality control during writing, (3) maintain consistency across chapters, (4) prepare a submission-ready manuscript, or (5) systematically execute a planned paper. Triggered by phrases like 'write the paper from this outline,' 'compose the full manuscript,' 'execute the outline,' or when users have completed strategic planning (academic-paper-strategist skill) and are ready to write. Takes optimized outline as input; outputs complete manuscript with iterative quality checks.
日本語の概要は準備中です。原文の説明を表示しています。
Multi-perspective academic paper review with dynamic reviewer personas. Runs a 5-seat, role-separated review panel (Journal-Fit Reviewer + 3 peer-review roles + Devil's Advocate) with field-specific expertise; role separation is not a claim of independent error processes. Supports full review, re-review (verification), quick assessment, methodology focus, Socratic guided, and calibration modes. Triggers on: review paper, peer review, manuscript review, referee report, review my paper, critique paper, simulate review, editorial review, calibrate reviewer, reviewer calibration, measure reviewer accuracy, 審查論文, 論文審查, 模擬審查, 同儕審查, 幫我審這篇, 以審查人角度評估, 審查者校準, 논문 심사, 동료 심사, 모의 심사, 심사자 관점에서 평가, 심사자 보정.
日本語の概要は準備中です。原文の説明を表示しています。
Systematic strategic planning framework for philosophy and interdisciplinary academic papers targeting preprint platforms (PhilArchive, arXiv, PhilSci-Archive). Use when users want to: (1) plan a paper on a specific topic, (2) identify research gaps and assess originality, (3) develop optimized paper outlines, (4) prepare for preprint submission, or (5) understand platform requirements and writing standards. Triggered by phrases like 'plan a paper on,' 'help me design a paper about,' 'identify research gaps in,' 'is this idea original,' or when users need structured research planning. The skill guides through three phases: Platform Analysis (identifying target venue and studying sample papers), Theoretical Framework (AI-driven literature search and gap identification), and Outline Optimization (structured design with reviewer-perspective self-assessment). Each phase includes quality evaluation standards and validation checkpoints.
日本語の概要は準備中です。原文の説明を表示しています。