“large models”的搜索结果

Predict B-cell and T-cell epitopes for vaccine antigen design and epitope mapping with BepiPred-3.0, DiscoTope-3.0, the IEDB tools, and EL-mode MHC presentation. Encodes the load-bearing asymmetry that T-cell epitope prediction is mature (it reduces to MHC presentation, AUC>0.9) while B-cell prediction is unreliable (linear predictors ~AUC 0.6 because ~90% of real epitopes are conformational) — so structure-based DiscoTope-3.0 on AlphaFold models is the only defensible B-cell path, propensity scales are obsolete, and NetChop is largely redundant on EL-trained models. Use when mapping epitopes or selecting vaccine antigens. MHC binding lives in mhc-binding-prediction.

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Predict B-cell and T-cell epitopes for vaccine antigen design and epitope mapping with BepiPred-3.0, DiscoTope-3.0, the IEDB tools, and EL-mode MHC presentation. Encodes the load-bearing asymmetry that T-cell epitope prediction is mature (it reduces to MHC presentation, AUC>0.9) while B-cell prediction is unreliable (linear predictors ~AUC 0.6 because ~90% of real epitopes are conformational) — so structure-based DiscoTope-3.0 on AlphaFold models is the only defensible B-cell path, propensity scales are obsolete, and NetChop is largely redundant on EL-trained models. Use when mapping epitopes or selecting vaccine antigens. MHC binding lives in mhc-binding-prediction.

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使用whisper在本地转录音频文件，保存为文本或生成翻译字幕，无需API密钥。可选择不同大小的模型，根据任务需求平衡处理速度与准确度。

• 将录音转录为可阅读的文本
• 根据音频制作翻译字幕
• 按速度或准确度需求选择模型

指导使用Axolotl对大语言模型进行微调，涵盖YAML配置、数据格式和训练方法，也可用于检查多GPU设置、排查训练故障及运行缓慢的问题。

• 编写微调用的YAML配置
• 了解LoRA和QLoRA训练方法
• 查阅数据格式和API用法

指导通过评价回答的强化学习对大语言模型进行后训练。结合Megatron-LM与SGLang，涵盖数据准备、并行执行及自定义生成流程。

• 开始语言模型的GRPO训练
• 并行运行回答生成与训练
• 训练使用工具的智能体

使用云端GPU运行机器学习训练、推理和数据处理，并将模型发布为API。通过Python定义运行环境，还可配置自动扩缩容、存储、并行处理和定时任务。

• 无需管理GPU服务器即可训练模型
• 将模型发布为自动扩缩容的API
• 并行处理大量数据

Set up reinforcement learning, which trains models using rewards, with verl. Follow workflows for preparing data, configuring GRPO or PPO training, scaling across GPUs, and addressing memory errors or unstable training.

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• Training a math reasoning model with GRPO
• Configuring PPO training with a critic model
• Scaling large model training across multiple nodes

Run machine learning workloads on Modal's cloud GPUs without managing servers. Guides Python configuration for training, inference, batch processing, and API deployment, including automatic scaling, persistent storage, scheduled jobs, and troubleshooting.

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• Running GPU inference without managing servers
• Deploying a model as an automatically scaling API
• Processing large batches in parallel

Configure large language model pretraining with torchtitan across multiple GPUs. Covers ways to split training work, launch jobs on computing clusters, enable Float8 numerical processing, and save or resume training through distributed checkpoints.

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• Pretraining Llama 3.1 8B on eight GPUs
• Configuring multi-node training with SLURM
• Enabling Float8 training on H100 GPUs

Guide substantial Swift changes in cmux with rules for package boundaries, dependency direction, state management, concurrency, and API documentation. Structure code so public package types can be tested without launching the app.

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• Extracting a large app feature into Swift Packages
• Reviewing dependencies between UI, domain models, and services
• Restructuring state management and Swift 6 concurrency

Write and debug code for further training large language models with TRL. Match training methods to dataset formats, configure supervised or preference-based training, and set up reward functions through Python or the command line.

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• Training a language model on example responses
• Training with preferred and rejected response pairs
• Debugging GRPO reward functions and batch settings

Plan projects that use large language models, from checking whether the task suits a model to designing processing stages. Estimate costs, choose single or multiple agents, and organize prototypes, structured outputs, and iteration.

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• Checking whether a task is suitable for an LLM
• Designing a pipeline for batch analysis
• Estimating processing costs before development

Build image conversations with LLaVA, a model that connects image recognition with language. This skill guides setup, image descriptions, visual questions, and follow-up conversations, with examples for Python, command-line use, and a Gradio interface.

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• Build a chatbot that answers questions about images
• Write detailed descriptions of photos
• Ask follow-up questions about the same image

Guides LLM training with verl using rewards to improve model responses. Covers data preparation, reward functions, GRPO and PPO configuration, distributed GPU training, and troubleshooting memory shortages or unstable training.

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• Train math reasoning models with GRPO and answer-based rewards
• Configure PPO training with a separate value-estimation model
• Run large-model training across multiple GPU nodes

Guides you through running large language models on CPUs, Apple Silicon, and AMD or Intel GPUs. Covers choosing GGUF model files, reducing memory through quantization, and starting an OpenAI-compatible chat server.

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• Running a local LLM on an Apple Silicon Mac
• Trying LLM inference on a CPU-only machine
• Choosing a model format that fits available memory

Configure large language model pretraining with torchtitan across multiple GPUs. Covers ways to split training work, launch jobs on computing clusters, enable Float8 numerical processing, and save or resume training through distributed checkpoints.

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• Pretraining Llama 3.1 8B on eight GPUs
• Configuring multi-node training with SLURM
• Enabling Float8 training on H100 GPUs

Run machine learning workloads on Modal's cloud GPUs without managing servers. Guides Python configuration for training, inference, batch processing, and API deployment, including automatic scaling, persistent storage, scheduled jobs, and troubleshooting.

中文简介正在准备中。当前显示英语简介。

• Running GPU inference without managing servers
• Deploying a model as an automatically scaling API
• Processing large batches in parallel

Write and debug code for further training large language models with TRL. Match training methods to dataset formats, configure supervised or preference-based training, and set up reward functions through Python or the command line.

中文简介正在准备中。当前显示英语简介。

• Training a language model on example responses
• Training with preferred and rejected response pairs
• Debugging GRPO reward functions and batch settings

This skill should be used at the start of any computationally intensive scientific task to detect and report available system resources (CPU cores, GPUs, memory, disk space). It creates a JSON file with resource information and strategic recommendations that inform computational approach decisions such as whether to use parallel processing (joblib, multiprocessing), out-of-core computing (Dask, Zarr), GPU acceleration (PyTorch, JAX), or memory-efficient strategies. Use this skill before running analyses, training models, processing large datasets, or any task where resource constraints matter.

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Build, deploy, evaluate, optimize, fine-tune, and manage Microsoft Foundry agents, models, and resources end to end. USE FOR: foundry, azd ai agent, azd provision/deploy, hosted agent scaffold/develop/run/deploy/troubleshoot, prompt agent create, managed harness agent create, GitHub Copilot harness agent, create agent, update agent, add tool to agent, invoke agent, agent insights, evaluate agent, batch eval, continuous eval, continuous monitoring, agent CI/CD, optimize prompt, improve prompt, optimize agent instructions, Agent Optimizer scaffold, dataset curation from traces, deploy model, model fine-tuning (SFT/DPO/RFT), Foundry project, RBAC, role assignment, permissions, quota, capacity, region, deployment failure, AI Services, create Foundry resource, knowledge index, customize deployment, onboard, availability, training-data, grader, distillation, large file upload. DO NOT USE FOR: Azure Functions, App Service, general Azure deploy (use azure-deploy), general Azure prep (use azure-prepare).

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Fine-tune models on Microsoft Foundry using SFT (supervised), DPO (preference), or RFT (reinforcement with graders). Covers dataset preparation, training job submission, deployment, and evaluation. USE FOR: fine-tune, SFT, DPO, RFT, training data, grader, distillation, fine-tuned model, training job, large file upload, calibrate grader, deploy fine-tuned model, evaluate fine-tuned model. DO NOT USE FOR: general model deployment without fine-tuning (use deploy-model), agent creation (use agents), prompt optimization without training (use prompt-optimizer).

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Fine-tune models on Microsoft Foundry using SFT (supervised), DPO (preference), or RFT (reinforcement with graders). Covers dataset preparation, training job submission, deployment, and evaluation. USE FOR: fine-tune, SFT, DPO, RFT, training data, grader, distillation, fine-tuned model, training job, large file upload, calibrate grader, deploy fine-tuned model, evaluate fine-tuned model. DO NOT USE FOR: general model deployment without fine-tuning (use deploy-model), agent creation (use agents), prompt optimization without training (use prompt-optimizer).

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Build, deploy, evaluate, optimize, fine-tune, and manage Microsoft Foundry agents, models, and resources end to end. USE FOR: foundry, azd ai agent, azd provision/deploy, hosted agent scaffold/develop/run/deploy/troubleshoot, prompt agent create, managed harness agent create, GitHub Copilot harness agent, create agent, update agent, add tool to agent, invoke agent, agent insights, evaluate agent, batch eval, continuous eval, continuous monitoring, agent CI/CD, optimize prompt, improve prompt, optimize agent instructions, Agent Optimizer scaffold, dataset curation from traces, deploy model, model fine-tuning (SFT/DPO/RFT), Foundry project, RBAC, role assignment, permissions, quota, capacity, region, deployment failure, AI Services, create Foundry resource, knowledge index, customize deployment, onboard, availability, training-data, grader, distillation, large file upload. DO NOT USE FOR: Azure Functions, App Service, general Azure deploy (use azure-deploy), general Azure prep (use azure-prepare).

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Parameter-efficient fine-tuning for LLMs using LoRA, QLoRA, and 25+ methods. Use when fine-tuning large models (7B-70B) with limited GPU memory, when you need to train <1% of parameters with minimal accuracy loss, or for multi-adapter serving. HuggingFace's official library integrated with transformers ecosystem.

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