“prioritization”的搜索结果

Advanced vulnerability analysis principles. OWASP 2025, Supply Chain Security, attack surface mapping, risk prioritization.

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Structured multi-criteria decision analysis for ranking options with weights, constraints, confidence, tradeoff reasoning, sensitivity analysis, and explainable recommendations. Use when the user asks for decision support, MCDA, weighted scoring, prioritization, vendor selection, route planning, hiring shortlist ranking, tool comparison, procurement decisions, or auditable agent decision logic.

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Automate AR workflows: aging analysis, collection prioritization, payment follow-ups, cash application, and bad debt forecasting.

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ADHD-friendly life management assistant for OpenClaw. Helps with daily planning, task breakdown, time management, prioritization, body doubling, dopamine regulation, and maintaining routines. Use when the user asks for help organizing their life, staying on top of tasks, beating procrastination, planning their day/week, managing overwhelm, or mentions ADHD-related challenges like time blindness, forgetfulness, difficulty starting tasks, or emotional dysregulation.

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Prioritizes rare-disease variants from trio/quad WES/WGS with de novo (DeNovoGear, Triodenovo), compound-heterozygous phasing (WhatsHap), mosaic VAF tiering, phenotype-driven ranking (Exomiser, Phen2Gene, AMELIE), ClinGen gene-disease validity gating, and ACMG SF v3.2 secondary findings reporting. Use when running diagnostic exome / genome pipelines, identifying candidate Mendelian disease genes, screening for incidental findings, or auditing VUS reclassification cycles. The ACMG/AMP classification framework (PVS1 decision tree, Pejaver PP3/BP4 calibration, Tavtigian point system) is in clinical-databases/acmg-classification.

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Estimates SNP heritability and partitions it across functional annotations, cell types, and loci from GWAS summary statistics or individual-level genotypes. Implements LDSC, stratified LDSC with the baseline-LD model, Finucane 2018 cell-type prioritization, LDAK SumHer, HDL, HESS local heritability, BOLT-REML, GCTA-GREML, graphREML, and Popcorn cross-population genetic correlation. Use when computing total h2_SNP from summary stats, partitioning heritability across functional categories, prioritizing trait-relevant tissues or cell types from ENCODE/Roadmap chromatin marks, reconciling LDSC vs LDAK enrichment estimates, computing local heritability with HESS, estimating genetic correlation between traits, or producing publication-grade enrichment with calibrated sensitivity to model assumptions.

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Maps GWAS-implicated loci to candidate effector (causal) genes by integrating variant-to-gene (V2G) features via Open Targets L2G (Mountjoy 2021), MAGMA gene-based association (de Leeuw 2015), FUMA SNP2GENE, cS2G combined SNP-to-gene scores (Gazal 2022), Polygenic Priority Scores (PoPS, Weeks 2023), FLAMES, INQUISIT, DEPICT, and enhancer-gene predictors (ABC, ENCODE-rE2G). Use when narrowing a GWAS lead locus to a candidate causal gene, picking between proximity, eQTL-based, and similarity-based prioritizers, integrating multi-evidence streams (fine-mapping, colocalization, ABC enhancer-gene, distance, chromatin), reconciling discordant L2G vs PoPS calls, prioritizing tissue-specific eQTL evidence, or triangulating across at least three independent lines of evidence for a publication-grade effector-gene nomination.

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Vulnerability analysis: OWASP Top 10, current threat landscape, supply chain security, attack surface mapping, risk prioritization. Use for security audits. NOT for STRIDE/CSO infra audits (mk:cso).

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Advanced vulnerability analysis principles. OWASP Top 10 baseline + current threat landscape awareness, Supply Chain Security, attack surface mapping, risk prioritization. Use when performing security audits, threat modeling, or OWASP reviews. NOT for STRIDE/CSO-mode infrastructure audits (see mk:cso).

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Use when ranking competing initiatives for a roadmap, breaking a tie between two features, or auditing a backlog for hidden low-value work via Reach × Impact × Confidence ÷ Effort.

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[Project Management] Use when a workflow step or the user asks for planned-work prioritization using RICE, MoSCoW or Value-Effort ranking.

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Ranks companies or accounts by strategic relevance and opportunity. Use when the user provides accounts and wants a priority score, tier, rationale, risks, and next action.

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Qualifies and scores B2B prospects against a supplied ideal customer profile. Use when the user provides a lead list, company records, prospect data, or qualification criteria and wants prioritization, fit analysis, or disqualification reasons.

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Map application security findings to OWASP Top 10 categories and generate remediation checklists. Use for normalized AppSec review outputs and category-level prioritization.

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Product leadership for scaling companies. Product vision, portfolio strategy, product-market fit, and product org design. Use when setting product vision, managing a product portfolio, measuring PMF, designing product teams, prioritizing at the portfolio level, reporting to the board on product, or when user mentions CPO, product strategy, product-market fit, product organization, portfolio prioritization, or roadmap strategy.

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Use for mission: define, prioritize, --tick, progress, scan.

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Structured decision making: Pro/Con matrix, weighted scoring, decision tree, scenario analysis, and Eisenhower matrix.

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Ordnet Büroaufgaben, Korrespondenz und Fristen ohne Bindung an eine bestimmte Office-App.

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Shape FriendlyBet product decisions, MVP scope, user stories, tournament flows, multi-sport expansion, pool mechanics, social competition loops, and feature prioritization. Use when planning what FriendlyBet should build, cut, sequence, or validate, especially for new sports, prediction formats, pool flows, leaderboards, sharing, or product strategy.

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Use when working with Codescene — codeScene behavioral code analysis including code health scoring, hotspot detection, change coupling analysis, and PR integration for code quality gates. Use when configuring CodeScene for codebase visualization, technical debt prioritization, and automated code review feedback.

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Use when working with Wiz — wiz cloud security posture management. Covers cloud security posture analysis, vulnerability prioritization, attack path analysis, compliance assessment, container security, and resource inventory. Use when assessing cloud security posture, investigating attack paths, prioritizing vulnerabilities, or auditing cloud compliance.

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Advanced vulnerability analysis principles. OWASP 2025, Supply Chain Security, attack surface mapping, risk prioritization.

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End-to-end post-GWAS causal inference pipeline orchestrating heritability partitioning, genetic correlation, Mendelian randomization with CHP-aware sensitivity (CAUSE / LHC-MR), colocalization, fine-mapping with SuSiE / FOCUS, mediation, TWAS triangulation, cis-pQTL drug-target MR, effector-gene prioritization (L2G / PoPS / cS2G), and GenomicSEM common-factor GWAS. Use when triangulating causal inference across multiple complementary methods, prioritizing tissues via stratified LDSC, nominating or de-risking drug targets, mapping a lead SNP to a candidate effector gene, modeling shared genetic architecture across correlated traits, or producing a STROBE-MR-compliant publication-grade evidence battery from GWAS summary statistics.

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Transform GWAS signals into drug targets and repurposing opportunities. Connects GWAS-significant loci to causal genes via fine-mapping/eQTL, then to druggable proteins via DGIdb/OpenTargets, then to existing drugs via ChEMBL. Use for GWAS-to-target hypothesis generation, druggable-fraction analysis of disease loci, and human-genetics-validated drug-repurposing prioritization.

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