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NGS CLI for ChIP/RNA/ATAC-seq. BAM→bigWig with RPGC/CPM/RPKM, sample correlation/PCA, heatmaps/profiles around features, fingerprints. For alignment use STAR/BWA; for peak calling use MACS2.
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Provides patterns to build declarative AI Services with LangChain4j for LLM integration, chatbot development, AI agent implementation, and conversational AI in Java. Generates type-safe AI services using interface-based patterns, annotations, memory management, and tools integration. Use when creating AI-powered Java applications with minimal boilerplate, implementing conversational AI with memory, or building AI agents with function calling.
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Agnes AI API 接入支持与问题排查 Skill。帮助新用户完成 Agnes AI API 的接入配置， 诊断和解决接入过程中遇到的认证、参数、响应、图像生成、视频生成等各类问题。 涵盖 Thinking 模式开启、视频长度调节、流式输出、工具调用等高级功能指导。 兼容 OpenClaw、Claude Code、Hermes、Codex 等工具链。 thinking、stream、tool calling、模型选择、Base URL、响应格式、timeout、超时、轮询、 FAQ、问题排查、调试、免费调用、RPM、video_id、task_id、Prompt 模板、提示词、 生图、生视频、图生图、文生图、图生视频、文生视频、灰度自检、1M 上下文、4K 图片、4K 图、4K、灰度、自检、反馈、Bug、issue、问题反馈、功能建议。
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> Generate, modify, and style React components from natural language using the Thesys SDK. Guides schema-driven UI generation, theme customisation, tool calling integration, and deployment to Vite, Next.js, or Cloudflare Workers. Use when the user says "generate UI", "create a component", "build an interface", "Thesys", "generative UI", or asks to turn a description into a React component.
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Build production OpenAI Realtime voice agents and low-latency spoken interactions with live audio sessions, WebRTC or WebSocket transport, voice activity detection, tool/function calling, prompt design, logging, consent, privacy, safety, latency, and cost controls. Use for speech-to-speech agents and live voice UX; do not use for separate request-based transcription, text-to-speech, or offline audio generation work.
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Build and evaluate low-latency spoken, multimodal, and translation experiences with Google Gemini Live API and Gemini Enterprise Agent Platform Live API. Use when a media-production or voice-agent workflow needs real-time audio input/output, barge-in, voice configuration, live transcription, live translation, tool/function calling during a spoken session, WebSocket session design, latency QA, quotas/cost review, or Google/Vertex data-governance tradeoffs.
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Build production realtime voice agents with Hume's Empathic Voice Interface (EVI): speech-to-speech sessions, empathic/prosodic response design, EVI 3 versus EVI 4-mini selection, WebSocket and SDK integration, tools/function calling, interruption/barge-in, turn-taking, transcripts/audio artifacts, pricing/limits, privacy, safety, consent, and QA.
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Mark and remove PCR/optical duplicates using samtools fixmate and markdup. Use when preparing alignments for variant calling or when duplicate reads would bias analysis.
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Comprehensive variant filtering including GATK VQSR, hard filters, bcftools expressions, and quality metric interpretation for SNPs and indels. Use when filtering variants using GATK best practices.
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Sort alignment files by coordinate or read name using samtools and pysam. Use when preparing BAM files for indexing, variant calling, or paired-end analysis.
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Call the free Agnes text model API for chat completions, streaming answers, coding help, tool-calling experiments, and OpenAI-compatible text generation. Use when the user asks for 免费文本, 免费的文本模型, free text API, Agnes text, Agnes-2.0-Flash, free LLM calls, or wants to use a free chat/completion model through an Agent skill.
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AI SDK for Python (the `ai` package). Use for Python model calls (LLMs, image, video, speech, embedding, transcription, reranking, or evaluation), agents, model interaction tests, tool calling, subagents, approvals, durable execution, telemetry, AI SDK UI backends, and custom providers.
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Cerebras Inference is a hosted LLM API that runs open models on Cerebras wafer-scale chips at thousands of tokens per second, through an OpenAI-compatible endpoint. Use when a user wants the lowest-latency chat, code completion or agent loop, asks how to call the Cerebras API or SDK, needs streaming, tool calling, strict JSON schema output or reasoning control, or hits a "model not found" error from a retired Cerebras model ID.
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Find the papers that answer a research query in Firecrawl's research paper index — a corpus of paper abstracts whose largest share is biomedical and life-science literature (PubMed, bioRxiv, medRxiv), alongside arXiv preprints in CS, physics, and math — using semantic search, semantic and structural expansion, and in-body verification. Use this skill for literature-finding and paper-retrieval tasks of any kind, including clinical, biomedical, drug, gene, disease, and other life-science questions, whether the answer is a single paper or a full multi-paper set. The index is reached only through the `firecrawl_research_*` MCP tools or the `firecrawl research` CLI subcommands. Calling `firecrawl_search` with its `categories` option set to `["research"]` is a different feature — it filters ordinary web search to research-affiliated websites (the list includes PubMed, bioRxiv, medRxiv, arXiv, and publisher sites) and returns page results from them, without querying the paper records in this index.
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Run 150+ AI apps via inference.sh CLI - image generation, video creation, LLMs, search, 3D, Twitter automation. Models: FLUX, Veo, Gemini, Grok, Claude, Seedance, OmniHuman, Tavily, Exa, OpenRouter, and many more. Use when running AI apps, generating images/videos, calling LLMs, web search, or automating Twitter. Triggers: inference.sh, infsh, ai model, run ai, serverless ai, ai api, flux, veo, claude api, image generation, video generation, openrouter, tavily, exa search, twitter api, grok
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Expert guide for Vercel AI SDK (Core, UI, RSC), streaming structured data, multi-provider model switching, tool calling loops, and React 19/Next.js 15 AI engineering / Panduan ahli Vercel AI SDK, streaming data terstruktur, dan integrasi AI pada React 19/Next.js 15.
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Find the papers that answer a research query in Firecrawl's research paper index — a corpus of paper abstracts whose largest share is biomedical and life-science literature (PubMed, bioRxiv, medRxiv), alongside arXiv preprints in CS, physics, and math — using semantic search, semantic and structural expansion, and in-body verification. Use this skill for literature-finding and paper-retrieval tasks of any kind, including clinical, biomedical, drug, gene, disease, and other life-science questions, whether the answer is a single paper or a full multi-paper set. The index is reached only through the `firecrawl_research_*` MCP tools or the `firecrawl research` CLI subcommands. Calling `firecrawl_search` with its `categories` option set to `["research"]` is a different feature — it filters ordinary web search to research-affiliated websites (the list includes PubMed, bioRxiv, medRxiv, arXiv, and publisher sites) and returns page results from them, without querying the paper records in this index.
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Stop and consult this skill whenever your response would include specific facts about Anthropic's products. Covers: Claude Code (how to install, Node.js requirements, platform/OS support, MCP server integration, configuration), Claude API (function calling/tool use, batch processing, SDK usage, rate limits, pricing, models, streaming), and Claude.ai (Pro vs Team vs Enterprise plans, feature limits). Trigger this even for coding tasks that use the Anthropic SDK, content creation mentioning Claude capabilities or pricing, or LLM provider comparisons. Any time you would otherwise rely on memory for Anthropic product details, verify here instead — your training data may be outdated or wrong.
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Paint an original image in a watercolor style by writing code, not by calling an image model. Use when the user asks you to draw, paint, sketch, or make a picture of something and there is no image-generation tool available, or when they ask for a painting, watercolor, or illustration you can iterate on. Do not use for charts, diagrams, UI mockups, or requests to edit an existing photograph.
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Author and run a durable AI chat agent with chat.agent from @trigger.dev/sdk/ai: the per-turn run loop, why you MUST spread ...chat.toStreamTextOptions() first, returning a StreamTextResult vs calling chat.pipe(), the two server actions (chat.createStartSessionAction + auth.createPublicToken), and wiring useChat to useTriggerChatTransport. Load this when building, modifying, or debugging a chat backend (the agent task or its lifecycle hooks) or its React transport, when declaring typed tools or custom data parts, or when migrating a plain AI SDK streamText route to chat.agent.
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Use whenever you need the Datagrok browser to actually execute JavaScript — adding viewers, filtering, modifying the view, or returning a result widget to the chat. Open this skill before calling the datagrok_exec tool.
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Runs a multi-model orchestration workflow led by the session's Fable or Claude Opus model. Sends menial tool-calling work to Haiku subagents, judgment work to Opus subagents at an effort matched to each task, and high-stakes or fresh-perspective questions to a GPT-6 Astra Codex peer. Detects the lead from session context; `--lead fable` or `--lead opus` overrides. Use to orchestrate, delegate, fan out, get a decorrelated Codex opinion, run a blind Opus-Codex cross-check, or act as tech lead.
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Consults Fable as an independent, read-only reviewer at an effort the caller matches to the question. The calling session (usually Opus, or Haiku) holds the task and escalates one decision point. Use before committing to an interpretation or a substantial piece of writing or analysis, when stuck or not converging, when changing approach, or as a final check on a finished task. Fallback for when the native advisor tool is unavailable. Not for a session already running Fable.
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Apple FoundationModels framework for on-device LLM — text generation, guided generation with @Generable, tool calling, and snapshot streaming in iOS 26+.
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