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Use when executing and reporting the analysis/interpretation for an American Anthropologist (AA) manuscript so it survives expert anonymous review — disciplined ethnographic/qualitative inference, honest interpretation, and (for biological/archaeological work) sound quantitative analysis. Guides analysis and interpretation norms; it does not fabricate evidence or quotations.
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Translation and interpretation as language meta-skills -- equivalence theory (Nida's formal vs. dynamic equivalence), translation strategies (borrowing, calque, transposition, modulation, adaptation), interpretation modes (simultaneous, consecutive, sight), source text analysis, register preservation, cultural adaptation, untranslatability and compensatory strategies, machine translation literacy, and back-translation for verification. Covers literary, technical, legal, and community interpreting contexts. Use when translating between languages, evaluating translation quality, teaching translation skills, or understanding the limits of cross-linguistic transfer.
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在AI的建议、计划、估算或分析后附上两三个简短问题，帮助用户在行动前检查数字、逻辑与缺失信息。问题紧扣回答中的具体内容，可直接向代理追问。
Analyze candidate sites where sugars may attach to proteins, review experimental evidence, and prepare prediction or structural shielding workflows. Supports mutation planning, antibody glycan comparisons, and interpretation of site-specific measurements while distinguishing candidates from confirmed modifications.
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Retrieve public evidence and linked publications for a supported genetic variant, or look up gene–disease relationships. Preserve sources, conflicting assertions, and explicit search outcomes so qualified professionals can review the findings.
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Analyze public blockchain records to assess crypto market conditions. Combine network activity, large-holder transfers, decentralized finance liquidity, and valuation measures into a report with indicator comparisons, a composite score, and an interpretation of market signals.
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Turn scattered research equations and notes into a structured derivation document. Clarify the target, assumptions, and notation; distinguish exact steps from approximations and interpretations; and report missing conditions or logical gaps when the derivation cannot be supported.
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Define a consistent process for unattended AI research using public sources. Limit clarification questions, show a search plan, distinguish facts from interpretations and assumptions, and keep reports structured so repeated investigations can be compared.
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Retrieve focused information from CIViC for cancer variant interpretation. It uses GraphQL, a way to request specific data fields, to inspect available data structures and turn targeted evidence results into concise summaries.
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Organize experiment goals, settings, metrics, and progress in existing Obsidian notes. Keep temporary logs in daily notes, promote stable findings into result notes, and connect evidence with interpretation and decisions about the next step.
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Design studies that combine quantitative data, such as surveys, with qualitative evidence, such as interviews. It recommends a suitable design and outlines study phases, participant selection, timing, and ways to combine findings into an integrated interpretation.
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Designs complete research plans that integrate clinical variables with multi-omics data from a user-provided biomedical direction. Always use this skill whenever a user wants to design, scope, or structure a study that combines clinical variables with transcriptomics, proteomics, metabolomics, epigenomics, or related omics layers for mechanism interpretation, biomarker development, risk stratification, treatment-response analysis, or translational use. It should define the clinical use case, alignment across data layers, feature-reduction and fusion logic, modeling route, mechanism-interpretation layer, validation ladder, and four workload configurations (Lite / Standard / Advanced / Publication+). Never fabricate datasets, accession numbers, sample counts, metadata completeness, platform coverage, literature references, PMIDs, DOIs, or validation status. Always include the mandatory Dataset Disclaimer immediately before any workflow section that mentions datasets or public resources.
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Generates complete conventional non-oncology bioinformatics research designs from a user-provided disease context, process-related gene family or biological theme, and validation direction. Use when a study centers on multi-dataset bulk transcriptome integration, DEG analysis, process-gene intersection, enrichment analysis, GSEA, PPI hub-gene prioritization, TF/miRNA regulatory networks, ROC-based biomarker evaluation, and immune infiltration analysis. Covers five study patterns (process-DEG discovery, enrichment/GSEA interpretation, hub-gene prioritization, regulatory-network and immune interpretation, multi-layer public validation) and always outputs Lite / Standard / Advanced / Publication+ with a recommended primary plan, stepwise workflow, figure plan, validation hierarchy, minimal executable version, publication upgrade path, and strictly verified literature retrieval.
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Generates complete phenotype-scoring bioinformatics research designs for any disease context and any user-defined phenotype, pathway, process, signature, or molecular program. Use when a study centers on gene-set or feature-set definition, intersection with DEGs or candidate features, phenotype scoring, feature selection, diagnostic or stratification assessment, immune or cellular-resolution interpretation, network analysis, and optional orthogonal validation. Covers five study patterns (signature discovery, phenotype scoring, feature selection, immune/cellular interpretation, multi-layer validation) and always outputs Lite / Standard / Advanced / Publication+ with a recommended primary plan, stepwise workflow, figure plan, validation hierarchy, minimal executable version, publication upgrade path, and strictly verified literature retrieval.
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Queries ClinVar for variant pathogenicity classifications, ClinGen VCEP curations, and somatic-vs-germline interpretations via REST API, weekly VCF, or bulk XML. Use when determining clinical significance, triangulating conflicting interpretations, or aggregating evidence against the ACMG/AMP framework with ClinGen SVI specifications.
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Statute and regulation interpretation framework. Use when reading statutes, classifying requirements, analyzing operative keywords, applying canons of construction, or mapping compliance obligations from legislative text.
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Interpret learning analytics data and translate dashboard findings into actionable teaching decisions. Use when reviewing LMS data, quiz patterns, or engagement metrics.
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Dream journal, interpretation, and lucid dreaming coach. Use when the user wants to talk to Oneira, requests the Dream Guide, or wants help with dream journaling, interpretation, or lucid dreaming.
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Clinical variant interpretation using ClinVar, ACMG guidelines, and pathogenicity predictors. Prioritize variants for diagnostic and research applications. Use when interpreting clinical significance of variants.
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Queries ClinVar for variant pathogenicity classifications, ClinGen VCEP curations, and somatic-vs-germline interpretations via REST API, weekly VCF, or bulk XML. Use when determining clinical significance, triangulating conflicting interpretations, or aggregating evidence against the ACMG/AMP framework with ClinGen SVI specifications.
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GitHub 解封 — 账号封禁/限制/恢复的领域操作系统。覆盖：(a) GitHub 官方政策体系 (TOS / 可接受使用政策 / Trust & Safety 执行模式 / 公开申诉路径 / 受制裁地区解读)；(b) 封号原因诊断学 (spam / abuse / 制裁误标 / 2FA 丢失 / ToS 违规 / 账号劫持误判 / ban evasion 等子类型 + 症状→原因映射 + 自我分诊压测)；(c) 申诉实操 craft (写一封能让 T&S 快速判误伤的英文申诉信 + 升级阶梯 + 法务介入边界 + Don'ts)；(d) 制裁与合规硬边界 (OFAC SDN 名单 / 哪些国家或地区真不可达 / VPN 误判路径 / 中国大陆不是美国制裁地区的反复重申)；(e) 中国大陆开发者特别处境 (sanctioned region 误标 + SMS 验证不支持 +86/+852 + Gitee/GitLab/Codeberg/JihuLab 备用迁移 + 私有自托管 Gitea/Forgejo)；(f) 真实案例库 (~30+ 公开案例分类拆解：误伤 / 真违规 / 制裁误标三类各自赔率与申诉成功路径)。伦理锚绝不软化：不教 ban evasion / 不教撒谎式申诉 / 真违规承认改进 / 丢 2FA 无恢复因子则诚实告知 / 中国制裁误标靠申诉不靠换 VPN / 申诉 6 个月窗口必算清 / 约 3% (业内估) 真违规恢复 vs 约 79% (业内估) 误伤申诉成功率分层标。 (GitHub Account Reinstatement — the domain operating system for GitHub (and analogous platform) account suspension, restriction, appeal, and recovery. Covers: (a) GitHub official policy architecture (TOS / Acceptable Use Policies / Trust & Safety enforcement patterns / public appeals pathways / sanctioned-region interpretation); (b) suspension-cause diagnostics (spam / abuse / sanctions mis-flag / 2FA loss / ToS violation / account hijack false-positive / ban evasion taxonomy + symptom→cause mapping + self-triage pressure test); (c) appeal craft (writing an English appeal letter that gets T&S to fast-track a false-positive ruling + escalation ladder + legal-engagement boundary + Don'ts); (d) sanctions and compliance hard boundaries (OFAC SDN list / which countries/regions are truly unreachable / VPN false-positive paths / China is NOT a US-sanctioned region — repeated emphasis); (e) mainland China developer special circumstances (sanctioned-region mis-flag + SMS verification does not support +86/+852 + Gitee/GitLab/Codeberg/JihuLab fallback migration + self-hosted Gitea/Forgejo); (f) real-case library (~30+ public cases with categorized analysis: false-positive / genuine violation / sanctions mis-flag, each with win-rate and appeal success path). Ethical anchors absolutely not softened: do NOT teach ban evasion (creating new accounts turns a temp ban into a permanent one — the single biggest mistake); do NOT teach social engineering or lying in appeals (misuse + actually confirms violation); genuine violations: admit + improve beats denial; lost 2FA + no recovery factor → do not pretend recovery is possible; China sanctioned-region mis-flag → fix via appeal, not repeated VPN switching; appeal form 6-month window must be counted carefully; historical 约 3% (业内估) genuine-violation recovery vs 约 79% (业内估) false-positive appeal success rate stratification must be honestly labeled. Anti-samples (explicitly describe harm, never endorse): developer permabanned for ban evasion / open-source team org-banned for personal attacks in public issues / cases where repeated VPN switching escalated risk-control severity.) Master OS — automated mastery of GitHub Account Reinstatement — the domain operating system for GitHub (and analogous platform) account suspension, restriction, appeal, and recovery. Covers: (a) GitHub official policy architecture (TOS / Acceptable Use Policies / Trust & Safety enforcement patterns / public appeals pathways / sanctioned-region interpretation); (b) suspension-cause diagnostics (spam / abuse / sanctions mis-flag / 2FA loss / ToS violation / account hijack false-positive / ban evasion taxonomy + symptom→cause mapping + self-triage pressure test); (c) appeal craft (writing an English appeal letter that gets T&S to fast-track a false-positive ruling + escalation ladder + legal-engagement boundary + Don'ts); (d) sanctions and compliance hard boundaries (OFAC SDN list / which countries/regions are truly unreachable / VPN false-positive paths / China is NOT a US-sanctioned region — repeated emphasis); (e) mainland China developer special circumstances (sanctioned-region mis-flag + SMS verification does not support +86/+852 + Gitee/GitLab/Codeberg/JihuLab fallback migration + self-hosted Gitea/Forgejo); (f) real-case library (~30+ public cases with categorized analysis: fa
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Interpret learning analytics data and translate dashboard findings into actionable teaching decisions. Use when reviewing LMS data, quiz patterns, or engagement metrics.
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Reviews an existing conjoint study for threats to inference and returns severity-ranked findings on design integrity, estimation, measurement error, external validity, and interpretation, including the guardrail against reading an AMCE as majority preference. Use when the user asks whether a conjoint design or analysis holds up, has referee comments on a conjoint, or wants a second opinion on estimation or interpretation. New designs go to conjoint-design, reshaping to conjoint-cleaning.
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Dream analysis expert covering Jungian, Freudian, and symbolic interpretation frameworks
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