Think and work like an expert Astrostatistician. Use when a task calls for Astrostatistician judgment. Reasons from selection functions, censored flux limits, and look-elsewhere trial factors through Cobaya/emcee/dynesty cosmology, GP-coupled exoplanet inference, Landy–Szalay clustering, photo-z σNMAD calibration, and SBI (sbi/LtU-ILI) while treating Malmquist bias, prior-driven tensions, and detrend-then-fit transit bias as first-class failure modes.
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K-Dense-AI/scientific-agents☆ 2202026년 10월 3일 업데이트
Detect and remove doublets from flow and mass cytometry data. Covers FSC/SSC gating and computational doublet detection methods. Use when filtering out cell aggregates before clustering or quantitative analysis.
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BioTender-max/awesome-bio-agent-skills☆ 2042026년 7월 2일 업데이트
End-to-end flow cytometry workflow from FCS files to differential analysis. Orchestrates compensation, transformation, gating/clustering, and statistical testing with CATALYST/diffcyt. Use when processing flow or mass cytometry data end-to-end.
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BioTender-max/awesome-bio-agent-skills☆ 2042026년 7월 2일 업데이트
Visualizes ChIP-seq data using deepTools (computeMatrix, plotHeatmap, plotProfile, bamCoverage, bamCompare), pyGenomeTracks (modern INI-driven track plots), Gviz (R browser-style), EnrichedHeatmap (ComplexHeatmap-based), ChIPseeker tag heatmaps, and IGV batch screenshots. Handles bigWig normalization choices (CPM, BPM, RPGC, spike-in scaled), bamCompare operations (log2 ratio, subtract, SES), k-means clustering of heatmaps for biological subgrouping, and spike-in-scaled tracks for global-shift experiments. Use when generating publication-quality ChIP-seq signal heatmaps, profile plots, genome-browser tracks, or comparing samples visually.
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BioTender-max/awesome-bio-agent-skills☆ 2042026년 7월 2일 업데이트
Detect and remove doublets (multiple cells captured in one droplet) from single-cell RNA-seq data. Uses Scrublet (Python), DoubletFinder (R), and scDblFinder (R). Essential QC step before clustering to avoid artificial cell populations. Use when identifying and removing doublets from scRNA-seq data.
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BioTender-max/awesome-bio-agent-skills☆ 2042026년 7월 2일 업데이트
ESM2 protein language model for sequence scoring, embeddings, and plausibility checks. Use this skill when: (1) Computing pseudo-log-likelihood (PLL) scores, (2) Getting protein embeddings for clustering, (3) Filtering designs by sequence plausibility, (4) Zero-shot variant effect prediction, (5) Analyzing sequence-function relationships. For structure prediction, use chai1-structure-prediction or boltz-structure-prediction. For QC thresholds, use protein-design-qc.
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BioTender-max/awesome-bio-agent-skills☆ 2042026년 7월 2일 업데이트
Structure similarity search with Foldseek. Use this skill when: (1) Finding similar structures in PDB/AFDB databases, (2) Structural homology search, (3) Database queries by 3D structure, (4) Finding remote homologs not detected by sequence, (5) Clustering structures by similarity. For sequence similarity, use uniprot BLAST. For structure prediction, use chai or boltz.
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BioTender-max/awesome-bio-agent-skills☆ 2042026년 7월 2일 업데이트
ESM2 protein language model for embeddings and sequence scoring. Use this skill when: (1) Computing pseudo-log-likelihood (PLL) scores, (2) Getting protein embeddings for clustering, (3) Filtering designs by sequence plausibility, (4) Zero-shot variant effect prediction, (5) Analyzing sequence-function relationships. For structure prediction, use chai or boltz. For QC thresholds, use protein-qc.
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BioTender-max/awesome-bio-agent-skills☆ 2042026년 7월 2일 업데이트
Runtime per-test healing with evidence: multi-attribute selector healing, environment-aware diagnosis, flake classification, quarantine management, and confidence-scored auto-repair. Goes beyond simple locator fallbacks to cover action-level healing, data healing, and observable repair workflows. Use when: "flaky test," "test stability," "self-healing locator," "broken locator recovery," "unreliable test," "quarantine flaky test." Not for: bulk regenerating selectors after a planned UI refactor — use selector-drift-recovery (this skill heals ONE test at runtime; that one rewrites many tests offline). Not for: classifying/clustering CI failures into bug reports — use ai-bug-triage. Related: playwright-automation, selector-drift-recovery, ci-cd-integration, qa-metrics, ai-bug-triage.
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petrkindlmann/qa-skills☆ 1982026년 10월 21일 업데이트
Audit a whole regression suite and prune/restructure it with evidence: per-test coverage fingerprinting, AST near-duplicate clustering, CI-history mining for never-failing and flaky tests, prune decision rules (redundant/obsolete/low-value/keep), smoke/core/extended tiering by risk and defect-detection history, and a defensible "what we deleted and why" record. Deletion is destructive — quarantine and human sign-off are mandatory. Use when: "audit the test suite," "prune redundant tests," "find duplicate tests," "which tests can we delete," "restructure into smoke/core/extended," "is this test pulling its weight," "shrink the regression suite." Not for: Judging whether an individual test is WELL-WRITTEN (smells, assertions) — that is ai-qa-review. Healing one flaky test at runtime — that is test-reliability. Bulk selector regeneration after a UI refactor — that is selector-drift-recovery. Related: ai-qa-review, coverage-analysis, test-reliability, risk-based-testing, qa-project-context.
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petrkindlmann/qa-skills☆ 1982026년 10월 21일 업데이트
对用户、产品等业务对象做分群:用波士顿矩阵法做象限分群,或用分层聚类、K-means、DBSCAN 等聚类技术分群。当需要做客群/产品分群、象限策略、画像或密度型子结构发现时调用。触发条件:当对话中出现“分群”、“分类”、“聚类”、“不同类型”、“不同场景”等体现分群分析词语时触发。
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agentscope-ai/QwenPaw-Data☆ 1582026년 10월 20일 업데이트
Detect keyword cannibalization across blog posts by extracting primary keywords from titles and headings, clustering semantically similar targets, and flagging posts competing for the same search intent. Supports local-only mode (grep-based) and DataForSEO API mode (Page Intersection endpoint at ~$0.01/call). Outputs severity-scored report with merge or differentiate recommendations. Use when user says "cannibalization", "keyword overlap", "competing pages", "duplicate keywords", "cannibalize".
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Infrasity-Labs/dev-gtm-claude-skills☆ 1422026년 6월 29일 업데이트
Cluster forces from multiple JTBD interviews to identify patterns. Use after extracting from multiple interviews.
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itseffi/agentic-os☆ 1172026년 10월 7일 업데이트
SEO, AEO (Answer Engine Optimization), and GEO strategy for search engines and AI visibility. Use when working on "SEO audit," "technical SEO," "on-page SEO," "AI search optimization," "AEO," "GEO," "AI visibility," "optimize for ChatGPT," "optimize for Perplexity," "AI Overviews," "answer engine optimization," "generative engine optimization," "AI citations," "featured snippets," "meta tags," "schema markup," "search ranking," "content optimization," "E-E-A-T," "structured data," "search console," "SEO health check," "why am I not ranking," "AI search readiness," "backlink strategy," "link building," "domain authority," "programmatic SEO," "SEO at scale," "template-based SEO," "AEO monitoring," "AI search monitoring," "JSON-LD," "rich snippets," "schema.org," "SERP analysis," "search intent," "site architecture," "information architecture," "URL structure," "internal linking," or "navigation." For keyword research, see keyword-research-and-clustering.
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manojbajaj95/claude-gtm-plugin☆ 1082026년 9월 18일 업데이트
Run metric-driven optimization loops. Use when improving measurable outcomes such as search relevance, clustering quality, build performance, prompt quality, or scored behavior through experiments.
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nota-america/forgecat-agent-profiles☆ 922026년 9월 24일 업데이트
Analyze LLM eval results — score breakdowns by category, regression detection vs baseline, failure clustering. Use when asked to "analyze our eval results", "did the model regress", or "cluster the eval failures".
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tonone-ai/tonone☆ 762026년 10월 15일 업데이트
Supervised and unsupervised learning, bias-variance tradeoff, cross-validation, decision trees, ensemble methods, neural network fundamentals, and the practitioner's workflow from problem framing through deployment. Covers classification, regression, clustering, dimensionality reduction, regularization, hyperparameter tuning, and evaluation metrics. Use when building predictive models, selecting algorithms, or understanding the machine learning pipeline.
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Tibsfox/gsd-skill-creator☆ 712026년 7월 20일 업데이트
Pick among candidate outputs (code, configs, plans) by running them on diverse inputs and clustering by behavioural fingerprint, rather than by textual aggregation or log-probability. Activates when an executor returns multiple plausible candidates that need disambiguation, when output-majority voting would be the default choice, or when reviewing generated code that has not yet been validated. The 2026 evidence (Semantic Voting, arxiv 2605.08680v1) is that any execution-based selector dominates output-majority voting by 19-52pp; sketch-generated inputs beat random fuzz by 11.3pp. Triggers: "pick the best candidate", "majority vote on code", "select from N samples", "validate the generated output", "behavioural verification".
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Tibsfox/gsd-skill-creator☆ 712026년 7월 20일 업데이트
This skill should be used for time series machine learning tasks including classification, regression, clustering, forecasting, anomaly detection, segmentation, and similarity search. Use when working with temporal data, sequential patterns, or time-indexed observations requiring specialized algorithms beyond standard ML approaches. Particularly suited for univariate and multivariate time series analysis with scikit-learn compatible APIs.
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plurigrid/asi☆ 702026년 7월 10일 업데이트
Configure Akka.NET with .NET Aspire for local development and production deployments. Covers actor system setup, clustering, persistence, Akka.Management integration, and Aspire orchestration patterns.
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ComeOnOliver/skillshub☆ 642026년 6월 24일 업데이트
Collaboratively brainstorm a topic by diverging on ideas, converging through clustering and scoring, and distilling a shortlist with a recommended direction. Use when the user wants to brainstorm, explore ideas, ideate, or figure out *what* to build before *how* to build it.
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rse/ase☆ 602026년 10월 22일 업데이트
Monitors market regime signals with volatility clustering, correlation dynamics, and liquidity condition assessment. Use when analyzing market regimes, detecting regime shifts, or adjusting strategy for market conditions.
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CaseMark/skills☆ 462026년 10월 17일 업데이트
Pythonic wrapper around RDKit with a simplified interface and sensible defaults. Preferred for standard drug discovery work — SMILES/SELFIES/InChI conversion, molecule standardization and sanitization, descriptors, ECFP and other fingerprints, Tanimoto distance matrices, Butina clustering and diverse subset picking, Bemis-Murcko scaffolds and scaffold splits, BRICS/RECAP fragmentation, 3D conformer generation, SDF/CSV/Excel and cloud I/O, and parallel processing via n_jobs. Returns native rdkit.Chem.Mol objects, so it composes with RDKit throughout. Also trigger on datamol, `import datamol as dm`, dm.to_mol, dm.standardize_mol, dm.cluster_mols, or dm.pick_diverse. For advanced control or custom parameters, use the rdkit skill directly.
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K-Dense-AI/drug-discovery-agent-skills☆ 452026년 10월 19일 업데이트
Expert coding skill for the full MapTiler platform — Cloud REST APIs, MapTiler SDK JS (built on MapLibre GL JS), native mobile SDKs, on-premise infrastructure, and vector tile schemas. USE WHEN the user wants to add a map to a web or mobile app, show locations or routes, display geographic data, build a store locator, create data visualizations on maps, add geocoding or address search, do reverse geocoding, look up elevation, do IP geolocation, fetch weather data, transform coordinates between CRS/EPSG, embed static map images, work with vector tilesets (Planet v4, Buildings, Contours, Outdoor, Ocean, Landcover, Cadastre), write MapLibre style expressions or data-driven styling, render 3D terrain, globe view, or 3D buildings extrusion, use satellite imagery, add markers, popups, heatmaps, or clustering, integrate maps in React, Vue, Svelte, Angular, Next.js, Leaflet, OpenLayers, Cesium, or deck.gl, build native maps on iOS (Swift), Android (Kotlin), Flutter, or React Native, self-host with MapTiler Server or generate tiles with MapTiler Engine CLI, or upload/manage tilesets via the Admin API. Also USE WHEN the user mentions MapLibre GL JS — the SDK extends MapLibre with built-in cloud services, helpers, and session billing.
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maptiler/maptiler-skills☆ 412026년 10월 21일 업데이트