Application of Six Sigma quality methodology to AI agent process improvement and reliability
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Application of Six Sigma quality methodology to AI agent process improvement and reliability
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Data structures and algorithms for AI agent episodic memory. Covers vector stores (HNSW, IVF, PQ), temporal indexing, knowledge graphs with triple stores, hierarchical summarization, forgetting curves, working/long-term/ procedural memory, and memory consolidation. Deep analysis of MemGPT/Letta, Zep/Graphiti, Mem0, and the Stanford generative agents memory architecture. Teaches the CS fundamentals behind how agents remember, retrieve, and forget. Activate on: "agent memory", "episodic memory", "vector search algorithm", "HNSW", "memory retrieval", "forgetting curve", "knowledge graph memory", "MemGPT", "Letta", "Zep", "Mem0", "memory consolidation", "temporal retrieval", "agent long-term memory", "memory layer". NOT for: conversation protocol design (use agent-conversation-protocols), agent infrastructure selection (use agentic-infrastructure-2026), building RAG pipelines (use ai-engineer).
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Data structures and serialization formats for agent-to-agent communication. Covers message envelopes, structured output schemas, capability declarations, task handoff payloads, error/retry signaling, and context windows as data structures. Deep comparison of A2A protocol, MCP, OpenAI function calling, and LangChain message types. Teaches when to use rigid schemas vs free-form with validation, typed vs untyped, streaming vs batch. Activate on: "agent message format", "agent communication schema", "agent-to-agent protocol", "A2A protocol", "MCP message format", "structured output for agents", "agent interop", "interchange format", "agent serialization", "task handoff format", "capability declaration". NOT for: what agents say to each other (use agent-conversation-protocols), orchestration topology (use multi-agent-coordination), building agent infrastructure (use agentic-infrastructure-2026).
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Expert in 3D computer vision labeling tools, workflows, and AI-assisted annotation for LiDAR, point clouds, and sensor fusion. Covers SAM4D/Point-SAM, human-in-the-loop architectures, and vertical-specific training strategies. Activate on '3D labeling', 'point cloud annotation', 'LiDAR labeling', 'SAM 3D', 'SAM4D', 'sensor fusion annotation', '3D bounding box', 'semantic segmentation point cloud'. NOT for 2D image labeling (use clip-aware-embeddings), general ML training (use ml-engineer), video annotation without 3D (use computer-vision-pipeline), or VLM prompt engineering (use prompt-engineer).
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Conversation patterns and interaction protocols for multi-agent systems. Covers request/response, pub/sub, blackboard, delegation chains, debate, critique, consensus, fan-out/fan-in, supervisor-worker, and peer negotiation. Deep analysis of AutoGen conversation patterns, CrewAI delegation, LangGraph state passing, and FIPA-ACL performatives. Teaches how to design what agents say to each other and in what order. Activate on: "agent conversation", "agent protocol", "multi-agent debate", "agent delegation", "supervisor worker pattern", "agent voting", "consensus protocol", "fan-out fan-in", "agent negotiation", "blackboard pattern", "agent dialogue", "conversation topology", "agent handoff". NOT for: wire format or serialization (use agent-interchange-formats), orchestration infrastructure (use agentic-infrastructure-2026), single agent behavior (use agentic-patterns).
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Designs Bayesian clinical trials including Phase I dose-finding (BOIN, CRM, EWOC, mTPI-2), meta-analytic-predictive (MAP) priors with robust mixtures for external data borrowing, EXNEX for basket trials, hierarchical models for safety AE (Berry-Berry), Bayesian platform trials (I-SPY 2, GBM AGILE, REMAP-CAP), and posterior probability stopping rules. Covers FDA Bayesian Devices Guidance (2010), FDA Bayesian Methodology in Drugs Draft (January 2026), BOIN Fit-for-Purpose qualification (December 2021), and Project Optimus dose-optimisation. Use when designing dose-finding studies, platform trials, or sensitivity analyses with informative priors.
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Discovers de novo motifs and tests known motif enrichment in ChIP-seq, ATAC-seq, or other peak sequences using HOMER, MEME-ChIP (STREME, CentriMo, TOMTOM, FIMO), monaLisa, and AME. Handles background selection (GC-matched, dinucleotide-shuffled, Markov order-2, peak-flanks), motif databases (JASPAR 2024 CORE PWMs, JASPAR 2026 deep-learning collection, HOCOMOCO v12, HOMER built-in), centrally-enriched motif testing, and differential motif analysis. Use when identifying TF binding motifs in peaks, testing for known TF enrichment, scanning for motif instances, comparing motif content between conditions, or interpreting motifs from deep learning models.
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Trains and applies base-resolution deep learning models on ChIP-seq / ChIP-nexus / CUT&RUN data. Uses BPNet (Avsec 2021 Nat Genet 53:354; soft motif syntax from ChIP-nexus), chromBPNet (Pampari A et al 2024 bioRxiv; bias-factorized base-resolution profiles), EnFormer (Avsec 2021 Nat Methods 18:1196; 196 kb input, ~100 kb effective receptive field), DeepSEA (Zhou 2015; multi-task CNN), and JASPAR 2026 deep-learning collection (1259 BPNet ChIP models). Performs in silico mutagenesis for variant-effect prediction, DeepLIFT/Grad attribution, and TF-MoDISco motif discovery from attribution scores. Use when predicting variant effects on TF binding, discovering soft motif syntax / cooperativity, integrating ChIP-seq with sequence-only predictions, or applying precomputed JASPAR Deep Learning models to new variants.
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Guides comorbidity-stratified selection of initial and further glucose-lowering medicines for adults with type 2 diabetes using the NICE NG28 (2026) framework, covering six clinical profiles: no relevant comorbidity, heart failure, atherosclerotic cardiovascular disease, early onset, obesity, chronic kidney disease, and frailty.
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Look up NHS England genomic tests for rare and inherited diseases. Use this skill whenever a clinician asks what genetic test to order for a condition, which genes are covered for a specific diagnosis, what commissioning category a genomic test falls under (Core, Specialised, or Highly Specialised), or which tests belong to a specialty group (Neurology, Cardiology, Endocrinology, etc.). Also trigger for questions like what panel is used for a condition, whether there is an NHS test for something, what the R number is for a condition, or whether anything has changed in the genomic test directory. Source: NHS England National Genomic Test Directory for Rare and Inherited Disease v9.0 (April 2026).
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Guides individualised HbA1c target-setting and identifies the correct intensification trigger for adults with type 2 diabetes using the NICE NG28 (2026) framework, covering standard targets, hypoglycaemia-risk adjustment, indications for target relaxation, and appropriate monitoring frequency.
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/cs:ai-act-readiness <system> — EU AI Act 6-question forcing interrogation. Use during AI-system intake, before EU deployment, or during annual compliance refresh as Article 113 obligations phase in (2025-02-02 / 2025-08-02 / 2026-08-02 / 2027-08-02).
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Use when building or modifying SwiftUI views, settings windows, menu-bar UIs, or any surface for the KIKA app — or any calm, premium app you want to feel the same way. Encodes the KIKA Design System v2 (June 2026) — a calm, premium, modern dark UI with first-class light mode, inspired by Cursor, Linear, and high-quality dev tools — that you can adopt or adapt for your own app. Apply it to keep color, typography, spacing, and component styling consistent.
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The case-law chronicle of this repo's major failures — symptom, root cause, evidence, status, and the rule each battle minted — so nobody re-fights a settled battle or re-proposes a rejected fix. Use when a bug/incident looks familiar ("didn't this happen before?"), when you're about to propose an approach that may have been tried and rejected (e.g. shipping a migration from a package), when someone asks "why does rule X exist" / "why is done-by-lgtm a thing" / "what was incident 988", or when a bug-archaeology run hits the shallow-clone wall and needs the pre-June-2026 history. Trigger phrases: "has this broken before", "why can't packages ship migrations", "why did graduation fail", "why is the green-build lesson a rule", "what did we learn from incident NN". (For a live "build is green but the app is broken" symptom, start at crouton-diagnostics-index. NB keep this description free of any space-then-hash sequence — an unquoted YAML scalar treats space-hash as a comment start and silently truncates.)
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Expert guidance on Apple Human Interface Guidelines (HIG). Covers iOS, macOS, and visionOS with 2026 Liquid Glass aesthetics and accessibility-first design.
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/cs:ai-act-readiness <system> — EU AI Act 6-question forcing interrogation. Use during AI-system intake, before EU deployment, or during annual compliance refresh as Article 113 obligations phase in (2025-02-02 / 2025-08-02 / 2026-08-02 / 2027-08-02).
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Knowledge base synthesized from the Guide to the Systems Engineering Body of Knowledge (SEBoK) v2.14 by the BKCASE Project. Use for the established systems-engineering canon: SE fundamentals and foundations (systems science, systems thinking, the systems approach, modelling/MBSE), the life cycle (ISO/IEC/IEEE 15288/24748/24774 process, development & agile approaches, model selection/tailoring), technical management, concept definition, architecture/realization (the Vee), V&V, maintenance/sustainment, SE standards, and the application contexts (product, service, enterprise, systems-of-systems, healthcare), plus enabling SE (business/team/individual), related disciplines, quality attributes/specialty engineering, implementation examples, and emerging knowledge. Good for grounding background, vocabulary, and prior-art positions across all eight SEBoK Parts. SCOPE LIMITS: this pack is SEBoK v2.14 only (released 2026-05-18); it synthesizes and signposts rather than reproducing the source — it does not reproduce ISO/IEC/IEEE standard text, is a curated guide (not a complete textbook), and is thin on AI-integration depth (Part 8 is a staging area, not settled practice). LICENCE: content is CC BY-NC-SA 3.0 — non-commercial use only, attribution to the BKCASE Project required, share-alike obligations carry forward.
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Knowledge base from NASA-STD-7009B (Standard for Models and Simulations) with implementation depth from NASA-HDBK-7009B. Use for M&S criticality and programmatics, development evidence and capability assessment, verification/validation domains, uncertainty and sensitivity, use-phase results assessment, risk-informed decision reporting, and handbook life-cycle products. Covers STD-7009B (2024-03-05) + HDBK-7009B (2026-02-03) synthesized notes only; does not replace program-specific TA direction, NPR 7150.2 software requirements detail, or full PRA methodology.
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Knowledge base from the DOE Order on Program and Project Management for the Acquisition of Capital Assets (DOE O 413.3 series). Use for Critical Decisions CD-0–CD-4, performance baselines, acquisition strategy and IPTs, cost/schedule/EVMS/PARS controls, risk-informed governance, reviews, and contractor requirements. Built from O 413.3C (2026-08-05), which cancels O 413.3B Chg 7 (2023-06-21); does not replace site-specific procedures, nuclear safety rules detail, or full estimating standards.
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Bindet das model-agnostische Computer-Use-Modul open-compute (Screenshot-Wahrnehmung, Windows-UIA-Elementklicks, sicherheitsgegatete Aktionen) fuer ALLE Agenten des Systems ein -- Claude Code, Codex und agy/Antigravity. Nutzen, wenn ein Dienst eine interaktive GUI- oder Browser-Aktion braucht, die kein reiner Text-/API-Weg loesen kann (Paradebeispiel: Tailscale-Reauth im Browser, sonstige Login-/Consent-Dialoge, Dialogfenster-Klicks). Standard ab 2026-08-02: open-compute statt Aufgeben oder Abwarten nutzen.
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Нарезать голосовые Антона из чата «00 Архив ГОЛОСА» на ОТДЕЛЬНЫЕ ВИДИМЫЕ СЕССИИ: одна голосовая = одна сессия, всегда. Триггеры «/voice-sessions», «/vs», «/голосовые», «обработай голосовые», «разбери голосовые за сутки», «нарежь голосовые на задачи», «нарежь на сессии», «голосовые в сессии», «process my voice notes», «cut voices into sessions». ⭐ ЖЕЛЕЗНОЕ ПРАВИЛО (anton 05.08.2026
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Пометить КАЖДУЮ сессию Claude Desktop (Code tab) ИКОНКОЙ её группы прямо в заголовке — «⚙️ Имя», «💰 Р+ Имя». Пока сайдбар-инструмент ccd_sidebar заперт серверным флагом (anthropics/claude-code#92621), иконка в имени = единственная видимая группировка. Триггеры "/session-groups", "/sg", "проставь группы сессиям", "разложи сессии по группам", "иконки сессий", "группы в заголовки", а также САМ на СТАРТЕ сессии, как только ясна тема (приказ Антона 10.09.2026: «мало пикселей на экране, нужна иконка»), и на /retro шаг 6a-кватер как перепроверка. Движок session_groups.py (0 LLM) строит план, переименовывает сессия через MCP set_session_title. НЕ путать с /sessions (что сейчас крутится) и /retro (закрытие).
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Онбординг КЛОДА нового внешнего лида/пира в наш Second Brain — вся цепочка одной командой: оформить TG-комнату (название по формуле,… Триггеры: “/peer-onboard“, “/peer-onboard <имя>“, “онбординг клода лида“, “подключи его клода“, “сделай его пиром“, “peer pilot для <имя>“, “onboard <name>'s claude“. 4-й прогон живого паттерна ([человек] ContextOS → [человек] OKO → [человек] [человек] → Jiten Oswal, 08.2026)
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- Фандрайз по методике Гонки: упаковать НАШ рейз/анонс/заголовок по каталогу приёмов Gonka/Либерманов (журналистское досье, anton голосом 26.08.2026)… Триггеры: “/gonka-fundraise“, “/gonka“, “гонка фандрайз“, “фандрайз по типу гонки“, “упакуй рейз“, “упакуй раунд“, “как подать сумму“, “заголовок про деньги“, “проверь их фандрайз“, “пирамида или продукт“, “package the raise“, “fundraise like gonka“
日本語の概要は準備中です。原文の説明を表示しています。