「agm」の検索結果

Extract nucleosome positions from ATAC-seq data using NucleoATAC, ATACseqQC, and fragment analysis. Use when analyzing chromatin organization, identifying nucleosome-free regions at promoters, or characterizing nucleosome occupancy patterns from ATAC-seq fragment size distributions.

日本語の概要は準備中です。原文の説明を表示しています。

Preprocesses cell-free DNA sequencing data including adapter trimming, alignment optimized for short fragments, and UMI-aware duplicate removal using fgbio. Applies cfDNA-specific quality thresholds and fragment length filtering. Use when processing plasma cfDNA sequencing data before downstream analysis.

日本語の概要は準備中です。原文の説明を表示しています。

Apply Hunt and Thomas-inspired pragmatic programming rules when improving engineering judgment, feedback loops, DRY knowledge, orthogonality, automation, or adaptability.

日本語の概要は準備中です。原文の説明を表示しています。

Apply meta-principles of software craftsmanship: DRY, orthogonality, tracer bullets, and design by contract. Use when the user mentions "best practices", "pragmatic approach", "broken windows", "tracer bullet", "software craftsmanship", "avoid technical debt", "code ownership", or "how do I become a better developer". Also trigger when evaluating build-vs-buy decisions, designing estimation approaches, or choosing between reversible and irreversible architectural decisions. Covers estimation, domain languages, and reversibility. For code-level quality, see clean-code. For refactoring techniques, see refactoring-patterns.

日本語の概要は準備中です。原文の説明を表示しています。

Japanese (and other non-Hollywood) screenwriting methods (日本编剧方法/原创剧本实战) — distilled from ten Japanese directors and writers in ゼロからの脚本術; Kosawa Ryota (three acts as 起承转合, speed by jumping), Uchida Kenji (beautiful structure, time-axis tricks), Miki Satoshi (small-material notebook, theme emerges later), Sono Sion, Omiya Ellie (dialogue from inner monologue), Kakei Masaya ("if + moreover"), Fukuda Yuichi (character = actor + flaw, audience as tsukkomi), Yokohama Satoko, Takahashi Izumi ("pain"), Yukisada Isao (situation-born originals); plus Arai Haruhiko (IP adaptation, "write what you're ashamed of"). Neighbours; sw-korean-french-screenwriting, ozu-screenplay-style. Use when writing an original Japanese-style script or TV drama, working from small material and fragments, choosing between structure-first and character-first methods, building a Japanese 企画書, designing comedy tsukkomi systems, or when Hollywood models feel wrong for a quiet, daily-life, non-goal-driven story.

Write game shaders from cross-engine fundamentals — the vertex→fragment pipeline, coordinate spaces, UV math, and common 2D/3D effects (tint, UV scroll, dissolve, outline, fresnel rim, vignette) in GLSL with HLSL equivalents. Use when the user mentions shaders, fragment/pixel shader, vertex shader, UV, GLSL, HLSL, or effects like dissolve, outline, or rim light.

日本語の概要は準備中です。原文の説明を表示しています。

Write Godot 4.7 shaders in the Godot Shading Language: canvas_item shaders for 2D and spatial shaders for 3D, with vertex/fragment functions, uniforms (source_color, hint_range), TIME/UV animation, and screen-reading via hint_screen_texture. Use when authoring .gdshader files, writing fragment/vertex code, making 2D/3D visual effects, or porting 3.x shaders (SCREEN_TEXTURE, hint_color) to 4.x.

日本語の概要は準備中です。原文の説明を表示しています。

Defragment a work calendar through a tool-using agent — find the meeting debt, propose the consolidation, and (approval-gated) execute the moves. Use when asked to defrag my calendar, get me focus time, audit my meetings, or fix my week. Produces the calendar audit (cost per meeting, fragmentation map), a defrag proposal with focus blocks, and an approval-gated execution plan.

日本語の概要は準備中です。原文の説明を表示しています。

Decides how to preprocess plasma cfDNA sequencing data so the recoverable signal survives - library-prep-aware fragment expectations (dsDNA vs ssDNA/adaptase prep), UMI/duplex consensus with fgbio (ExtractUmisFromBam, GroupReadsByUmi --strategy paired for duplex, CallMolecularConsensusReads vs CallDuplexConsensusReads, FilterConsensusReads min-reads "total s1 s2"), the align->group->consensus->RE-align ordering, and the cfDNA dedup trap where naive coordinate dedup collapses nucleosome-coincident independent molecules. Covers when single-strand consensus suffices vs when duplex is mandatory, the singleton/sensitivity tax at low input, and reading the insert-size histogram as a pre-analytical QC instrument. Use when processing plasma cfDNA reads before fragmentomics, ctDNA mutation calling, or tumor-fraction estimation.

日本語の概要は準備中です。原文の説明を表示しています。

Protect, design, and measure focused work — block defence, session structure, interruption budgets, and deep-work ratio. Use when the calendar is fragmented, focus blocks keep getting eaten, or output has stalled.

日本語の概要は準備中です。原文の説明を表示しています。

文本内部重复片段模糊清理工具。读取 JSONL 文本数据，按文本字段删除近似重复的段落、句子或连续片段，保留首次出现内容并输出清理后的样本。 当用户提到清理重复片段、删除重复段落、去掉近似重复内容等需求时使用此 skill。 即使用户没有明确说出 "duplicate_fragment_cleaner"，只要任务涉及同一文本内部的重复片段清理，就应该使用此 skill。 不负责跨记录去重、摘要改写或语义重写。

日本語の概要は準備中です。原文の説明を表示しています。

Use when you've fixed a bug, added a feature, or made any user-facing change in a project that uses Towncrier and need to record it for the changelog — before committing or opening a PR, or whenever asked to add a changelog entry, towncrier fragment, or news fragment.

日本語の概要は準備中です。原文の説明を表示しています。

Writing, explore: mine raw fragments, no structure yet.

日本語の概要は準備中です。原文の説明を表示しています。

Preprocesses cell-free DNA sequencing data including adapter trimming, alignment optimized for short fragments, and UMI-aware duplicate removal using fgbio. Applies cfDNA-specific quality thresholds and fragment length filtering. Use when processing plasma cfDNA sequencing data before downstream analysis.

日本語の概要は準備中です。原文の説明を表示しています。

CustomShader authoring — vertexShaderText and fragmentShaderText against VertexInput, FragmentInput, FeatureIds, Metadata, czm_modelMaterial. Use when reading EXT_mesh_features or EXT_structural_metadata property textures/tables, vertex displacement, or shading VoxelPrimitive.

日本語の概要は準備中です。原文の説明を表示しています。

Writing, explore: mine raw fragments, no structure yet.

日本語の概要は準備中です。原文の説明を表示しています。

Expert mobile game developer specializing in iOS and Android game optimization, touch input design, battery and thermal management, device fragmentation handling, and App Store/Play Store submission. Deep knowledge of mobile-specific constraints and best practices for shipping performant, player-friendly mobile games. Use when "mobile game, ios game, android game, touch input, mobile optimization, mobile performance, app store, play store, mobile battery, thermal throttling, mobile porting, tablet game, phone game, mobile monetization, mobile build, mobile, ios, android, touch, optimization, performance, battery, thermal, app-store, play-store, game-development, unity-mobile, godot-mobile, device-fragmentation" mentioned.

日本語の概要は準備中です。原文の説明を表示しています。

Writing, explore: mine raw fragments, no structure yet.

日本語の概要は準備中です。原文の説明を表示しています。

"Apply pragmatist philosophy (Peirce, James, Dewey) to frame knowledge as instrumental for action, evaluate ideas by their practical consequences, and conduct inquiry as problem-solving. Use this skill when the user needs to bridge theory and practice, evaluate competing theories by their usefulness, employ abductive reasoning to generate hypotheses, or when they ask 'which theory is more useful here', 'how do I move from abstract ideas to actionable knowledge', or 'what practical difference does this distinction make'.".

日本語の概要は準備中です。原文の説明を表示しています。

Set up, format, fix, and clean up LaTeX regression and estimation tables in empirical economics or finance papers. Use when (a) creating a .tex, results.tex, main.tex, or preamble to display regression or estimation output from Python (pyfixest), Stata, or R — including any mention of estout, esttab, estauto, estwide, or table fragments; (b) formatting or repairing estout-style regression tables that overflow the right margin, have cramped or boxed notes, misaligned columns, or poor significance stars, or when asked to match a reference paper, make the note fill the table width, or choose among \estwide, \estauto, and landscape layouts; (c) diagnosing "Misplaced \omit" errors from \input-ed table fragments inside tabular environments. Covers \@@input, \estwide, \estauto, \estautoLT, \specialcell, \sym, minipage notes below tabulars, and the convert-and-verify workflow. Do NOT trigger for general LaTeX documents like beamer presentations, problem sets, letters, or CVs.

日本語の概要は準備中です。原文の説明を表示しています。

Zero-dependency live-preview server providing an agent↔browser bidirectional companion. Watches a content directory, wraps HTML fragments in a frame template, broadcasts live-reload over WebSocket, and captures browser-side click events to a JSONL file. Use when an agent needs to show HTML to the user in a browser and react to clicks — mockups, design exploration, gallery browsing, multi-select choices, prototype iteration. Triggered by "live preview", "browser companion", "preview server", "browser mockup", "show in browser", "arkhe-preview", or any skill that wants to write HTML fragments and have the user see them reload in real time.

日本語の概要は準備中です。原文の説明を表示しています。

Metal/wgpu/WGSL shader surfaces for native Rust gpui apps (Zed-family, pd-console), stockpiled with beautiful copy-pasteable shader-toy examples. Use for custom GPU fragment passes behind/around gpui panes: ocean/water shaders, pixelated waves and boats, a living harbor, dithered chrome borders, sonar sweeps, aurora/starfields, CRT/scanline post. Trigger on: wgsl, wgpu, metal shader, gpui shader, shadertoy, fragment shader, SDF, noise/fbm, ordered dithering, pixelation, render-to-texture, "pixelated waves and boats", living harbor water. NOT for: web/GLSL/three.js shaders (use a web tool), non-shader gpui motion (use rust-gpui-motion), general GUI layout/color (use beautiful-gui-design), CLI/TUI (use beautiful-cli-design).

日本語の概要は準備中です。原文の説明を表示しています。

Decides how to preprocess plasma cfDNA sequencing data so the recoverable signal survives - library-prep-aware fragment expectations (dsDNA vs ssDNA/adaptase prep), UMI/duplex consensus with fgbio (ExtractUmisFromBam, GroupReadsByUmi --strategy paired for duplex, CallMolecularConsensusReads vs CallDuplexConsensusReads, FilterConsensusReads min-reads "total s1 s2"), the align->group->consensus->RE-align ordering, and the cfDNA dedup trap where naive coordinate dedup collapses nucleosome-coincident independent molecules. Covers when single-strand consensus suffices vs when duplex is mandatory, the singleton/sensitivity tax at low input, and reading the insert-size histogram as a pre-analytical QC instrument. Use when processing plasma cfDNA reads before fragmentomics, ctDNA mutation calling, or tumor-fraction estimation.

日本語の概要は準備中です。原文の説明を表示しています。

On-demand "what's new" generator. Main context (which knows the impending change) writes keepachangelog-style entries to a fragment file at `.claude/state/whatsnew/<slug>.json` (gitignored, transient). An optional per-project `project.json → whatsnew.route_workflow` names a routing workflow that consumes the fragment and renders it wherever the project wants (a site page, a release body, a docs page). Not a workflow phase — it never blocks a commit, and it never writes `CHANGELOG.md` (that file is owned solely by semantic-release in CI).

日本語の概要は準備中です。原文の説明を表示しています。