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概要と使いどころ
Use when a task needs the judgment of a billing and posting clerk — generating an invoice against a rate/contract schedule, applying an incoming payment across multiple open invoices, processing a credit memo or adjustment, or investigating an aging-report discrepancy.
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Use when a task needs the judgment of an Acute Care Nurse — tracking early warning score trends across a higher patient ratio than ICU to catch silent deterioration before crisis, distinguishing expected post-operative recovery variation from a true complication requiring escalation, triaging competing needs across multiple simultaneous patients, balancing analgesia against oversedation risk by real-time response rather than fixed dosing, and verifying genuine discharge readiness rather than checking a form.
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Guide for multi-experiment batch operations: QC screening, batch download, comparison, and report generation across many ENCODE experiments simultaneously. Use when users need to process 5+ experiments together, create experiment comparison tables, perform batch quality checks, or generate summary reports. Trigger on: batch analysis, multiple experiments, bulk processing, experiment comparison, batch QC, multi-sample, batch download, experiment table, summary report, collection analysis.
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Conduct rigorous cross-study meta-analysis of scRNA-seq data from ENCODE, integrating multiple single-cell transcriptomic datasets for a tissue/cell type. Use when the user wants to answer "what cell types exist in my tissue and what genes define them?" by combining scRNA-seq data across donors, labs, and platforms. Follows the Mawla et al. 2019 framework for assessing cross-study reproducibility, TIN-based quality filtering, and detection-limit-aware interpretation. Handles batch correction (Harmony/Seurat), dropout awareness, cross-contamination artifacts, and platform-specific biases. Use this skill for ANY scRNA-seq integration task, cross-dataset comparison, cell atlas construction, or reproducibility assessment involving ENCODE single-cell data.
日本語の概要は準備中です。原文の説明を表示しています。
Integrate multiple ENCODE data types (RNA-seq, ATAC-seq, Histone ChIP-seq, TF ChIP-seq) for a tissue/cell type to build a comprehensive regulatory landscape. Use when the user wants to answer "what are the enhancers, promoters, and regulatory elements active in my tissue, and which transcription factors control them?" by layering expression, chromatin accessibility, histone marks, and TF binding data. Follows the Mawla et al. 2023 framework for cross-assay integration of islet cell type-specific data. Handles chromatin state annotation (ChromHMM), enhancer-gene linkage, TF motif enrichment, and cell type-specific regulatory element identification. Use for ANY multi-omic analysis, enhancer discovery, regulatory network construction, or epigenomic characterization using ENCODE data.
日本語の概要は準備中です。原文の説明を表示しています。
Plan and execute integrative analysis combining multiple ENCODE experiments for cross-dataset or multi-omic workflows. Use when the user wants to combine experiments, perform cross-dataset comparison, multi-omic integration, peak overlap analysis, differential binding, signal correlation, chromatin state segmentation, enhancer-gene linkage, or any analysis that requires merging or comparing data from two or more ENCODE experiments. Covers same-assay cross-sample, multi-omic same-sample, cross-organism, and perturbation integration designs. Guides compatibility checks, batch effect detection, normalization, integration strategy selection, and provenance documentation.
日本語の概要は準備中です。原文の説明を表示しています。
Build comprehensive chromatin contact maps by aggregating Hi-C loop calls (BEDPE) across multiple ENCODE experiments, donors, and labs. Use when the user wants to answer "what regions are in 3D contact in my tissue?" by creating a union catalog of chromatin loops. Handles resolution-aware anchor matching, cross-lab variation, and Hi-C-specific quality metrics.
日本語の概要は準備中です。原文の説明を表示しています。
Build comprehensive DNA methylation maps by aggregating WGBS (Whole Genome Bisulfite Sequencing) data across multiple ENCODE experiments, donors, and labs. Use when the user wants to answer "where is DNA methylated/unmethylated in my tissue?" by combining per-CpG methylation data into tissue-level methylation profiles. Handles coverage filtering, identifies hypomethylated regions (HMRs) and partially methylated domains (PMDs), and manages cross-lab variation.
日本語の概要は準備中です。原文の説明を表示しています。
Build comprehensive chromatin accessibility maps by aggregating ATAC-seq and DNase-seq narrowPeak data across multiple ENCODE experiments, donors, and labs. Use when the user wants to answer "where is chromatin accessible in my tissue?" by combining peak calls into a union peak set. Handles cross-lab variation, ATAC vs DNase platform differences, and ENCODE blocklist filtering.
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Rapid UI prototyping — generates 3 visually distinct HTML/CSS components from a text prompt and serves them in a live browser gallery. Use when user runs /prototype, asks to "prototype a UI", "mock up a component", "generate HTML mockups", "create UI variations", "design exploration", "quick UI concept", or wants to see multiple visual approaches to a component. Also trigger when user says "show me different ways to build...", "explore different designs for...", or wants rapid visual exploration of a UI idea — even without saying "prototype" explicitly.
日本語の概要は準備中です。原文の説明を表示しています。
Analyzes git commit history and generates professional changelogs with semantic versioning, conventional commit support, and multiple output formats (Keep a Changelog, Conventional, GitHub). Use when editing CHANGELOG.md, CHANGELOG.txt, or HISTORY.md files, preparing release notes, creating releases, bumping versions, updating changelog, documenting changes, writing release notes, tracking changes, version bump, tag release, or when user mentions "changelog", "release notes", "version history", "release", "semantic versioning", or "conventional commits".
日本語の概要は準備中です。原文の説明を表示しています。
Use this skill whenever the user wants to do anything with PDF files. This includes reading or extracting text/tables from PDFs, combining or merging multiple PDFs into one, splitting PDFs apart, rotating pages, adding watermarks, creating new PDFs, filling PDF forms, encrypting/decrypting PDFs, extracting images, and OCR on scanned PDFs to make them searchable. If the user mentions a .pdf file or asks to produce one, use this skill.
日本語の概要は準備中です。原文の説明を表示しています。
Archive multiple completed OpenSpec changes at once. Use when archiving several parallel changes. Also use for a plural archive request - "openspec bulk-archive", "opsx bulk-archive", "openspec archive all", or "openspec archive these changes".
日本語の概要は準備中です。原文の説明を表示しています。
Turns a single feature idea, improvement, or bug into ONE well-structured GitHub issue. TRIGGER when: the user wants to file/open/create an issue, turn a feature idea or improvement into a ticket, or capture something missing or broken as a ticket. DO NOT TRIGGER when: breaking work into multiple issues or planning a body of work → a planning skill; writing a full Product Requirements Document → creating-prd; the idea is still fuzzy and unhardened → grilling-ideas first.
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Generate an institutional-grade commercial real estate underwriting model — input schema (T-12 income, T-3 trailing, rent roll, debt terms, exit assumptions), calc engine (Cap Rate, NOI, Cash-on-Cash, IRR, DSCR, Debt Yield, ROI, Equity Multiple, levered & unlevered returns).
日本語の概要は準備中です。原文の説明を表示しています。
Detect content cannibalization on a site — multiple URLs ranking (or impressing) for the same query, splitting click-through, diluting authority, and confusing Google about which URL is canonical for the intent..
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Synthesize sprint retrospective notes into categorized action items and patterns. Use this skill when: - You have sprint retro notes (raw text, meeting transcript, or structured notes) to process - You need to identify recurring patterns across multiple retros - You want categorized action items with owners and deadlines from retro discussions
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Write paid ad copy for LinkedIn, Google, Meta, and YouTube. Produces multiple variants per platform, each targeting a different Eugene Schwartz awareness level and Cialdini persuasion principle. Use when the user asks for ad copy, ad variants, "write LinkedIn ads", Google ads, Meta ads, paid social copy, ad headlines, or wants creative for a paid campaign. Reads brand voice, ICP, and positioning from knowledge/. For organic social posts, see linkedin-post or social-calendar. For the landing page the ad points at, see landing-page-writer. For testing variants, see ab-copy-writer.
日本語の概要は準備中です。原文の説明を表示しています。
Generate A/B copy variants grounded in Eugene Schwartz's awareness and market-sophistication stages and John Caples' tested-headline discipline. Every variant declares its angle, the awareness stage it targets, and a falsifiable hypothesis, and the skill recommends which pair to test first and what delta counts as signal. Use when the user says "A/B test this", "write variants", "give me options", "test different angles", "copy variants", "ab copy", "test this headline", "multiple versions", "which version is better", or wants to test copy before publishing. For reviewing copy that already exists, see copy-review. For sample size and stopping rules, see growth-experiment. For diagnosing a page rather than its words, see page-cro. For full paid ad sets by platform, see ad-campaign-writer.
日本語の概要は準備中です。原文の説明を表示しています。
Convert Confluence pages to clean GitHub-Flavored Markdown files. Use this skill whenever the user wants to pull a Confluence page into the local repo, convert Confluence content to markdown, download a spec from Confluence, or batch-convert multiple pages. Also triggers on Confluence URLs, page IDs, or phrases like "pull this page", "download this spec", "confluence to md". Use this even if the user just pastes a Confluence URL and says something vague like "get this" or "convert this".
日本語の概要は準備中です。原文の説明を表示しています。
Use this skill when asked to work with an unfamiliar public website and the goal is to make progress generically before writing site-specific rules. It teaches Copilot how to probe controls, classify UI patterns, try multiple search and navigation strategies, follow popups, and only create a site profile when the generic approach is no longer sufficient.
日本語の概要は準備中です。原文の説明を表示しています。
**WORKFLOW SKILL** — Risk awareness before action. USE FOR: assessing risks (security, data integrity, compatibility, operational, reversibility) of any task at variable depth. Accepts weight: Light (quick scan), Standard (dimensional analysis), Deep (full Risk Radar with evidence). Can be invoked multiple times in the same flow with increasing weight. DO NOT USE FOR: penetration testing, compliance audits, static security analysis tools.
日本語の概要は準備中です。原文の説明を表示しています。
One-command multilingual blog creation. Writes a blog post, translates it into user-specified languages, applies cultural adaptation, and emits hreflang tags, sitemap entries, and a CMS-ready language map. The complete write-to-publish pipeline for international content. Orchestrates blog-write, blog-translate, blog-localize, and (optionally) seo-hreflang. Use when user says "multilingual blog", "blog multilingual", "write in multiple languages", "international blog", "mehrsprachiger Blog", "blog multilingue", "blog multilingue", "create blog in German and French".
日本語の概要は準備中です。原文の説明を表示しています。
Use when you need Codex to coordinate multiple agents through Agent Relay for peer-to-peer messaging, lead/worker handoffs, or shared status tracking across sub-agents and terminals.
日本語の概要は準備中です。原文の説明を表示しています。