429 件 ・ 関連度順
概要と使いどころ
Reference for the EBCDIC "overpunch" / zoned-decimal sign convention where the units position of a numeric field is replaced with a letter that encodes both a digit and a sign. Useful when reading mainframe-style fixed-length tapes whose amount fields appear as digits followed by a letter (e.g. "0000000000123D" or "0000000000045M").
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Automated Big-O complexity analysis of code and algorithms. Performs static analysis of loop structures, recursive call trees, space complexity estimation, and amortized analysis with detailed derivation documents.
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Draw cloud architecture diagrams for AWS, Azure or GCP with the official provider icon sets, using TerraVision. Use whenever the user asks to draw, diagram, sketch or visualize a system on AWS, Azure or Google Cloud, or one built from their services (Lambda, DynamoDB, S3, EC2, EKS, RDS, API Gateway, Azure Functions, App Service, AKS, Cosmos DB, Cloud Run, GKE, BigQuery and the like), even if they never say 'cloud', 'diagram' or a tool name; also for a diagram of Terraform code. Prefer it over Mermaid, PlantUML, hand-written SVG or ASCII, which cannot use the official icons or VPC/subnet grouping. Not for diagrams that are not cloud infrastructure: sequence diagrams, flowcharts, class or ER diagrams, code or module structure, org charts, on-premises-only networks; use Mermaid or similar for those. Works with or without Terraform: with Terraform code the diagram comes from terraform plan; without it, write a small JSON graph and render it.
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The screenwriting business and career (编剧行业与生意经) — merged from Diamond & Weissman's Bulletproof (buyer's-eye workflow, three Cs, one-page nine-step, set pieces, submission, notes, resilience), Eric Bork's The Idea (PROBLEM seven-element idea test, 60/30/10, television differences), Neill Hicks (market four entities, six criteria, WGA, agents, option, credit arbitration, gross vs net, step deals), Richard Walter (query letter, agents, package, option, spec, release, copyright, guild, gatekeepers, professionalism, 66 principles), Wendy Henson (breaking in), Blake Snyder (logline pitch, genre, agents), Julian Hoxter (industry terms), Mei Feng's Oscar analyses, and the Hollywood masterclass (pitching, notes, credits, TV vs film). Use when evaluating whether an idea is sellable, writing a logline/query/pitch, preparing a submission, handling notes and rewrites, understanding options/credits/WGA/agents/net profit, choosing between film and TV, or building a career strategy.
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Case studies of television series writing (剧集案例库) from primary texts; Sorkin's six West Wing teleplays (act-page tables, eight act-out types); Chase's five Sopranos scripts (the 35-beat A/B/C/D recipe, what a pilot refuses to explain); Fellowes's annotated Downton Abbey season two (19 storylines, 419 footnotes); Waller-Bridge's Fleabag Scriptures (the six-episode half-hour template); Calvisi's eight minute-by-minute pilot beat sheets (Breaking Bad, Mad Men, Game of Thrones and more); Landau's 47-series structure appendix; Miller's Hannibal and HTGAWM breakdowns; Goldberg & Rabkin's beat sheets; Sakamoto Yuji's We Made a Beautiful Bouquet (a feature) and Noh Hee-kyung's The Most Beautiful Goodbye. Use when you want a worked example of how an episode or pilot is built, need real act lengths, scene counts or storyline grids to imitate, are breaking a multi-thread ensemble episode, designing a bottle episode or a finale, writing a relationship or family drama, or ask 某一集是怎么写的 / 这部剧的结构表.
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Worked qupai-system (曲牌体) opera scripts, act by act. Guan Hanqing's three surviving zaju (窦娥冤／救风尘／金线池 — twelve acts, 126 tunes, one mode and one rhyme per act, sung/spoken ratios); Tang Xianzu's 牡丹亭 (55 scenes, ~420 tunes, 集唐 closing quatrains, the 圆驾 south-north composite suite); Kong Shangren's 桃花扇 (44 scenes plus four unnumbered, the 副末 frame line, upper/lower halves, a fan's seven transformations, his sixteen 凡例); 长生殿 (Wang Jilie's fifty-scene staging table); Wei Minglun's 巴山秀才 (1983 Sichuan 高腔, 43 tunes, nine 帮腔 passages). Every case states its edition and collation status, then structure, tunes, stage conventions and transferable devices. Method is in sw-chinese-opera-qupai; this skill holds the worked scripts. Use when you want a real example of how a 传奇 or 杂剧 is assembled, need actual scene counts and tune counts to imitate, are judging where a famous script breaks prosody, or need models for 副末开场, 集唐下场诗, 南北合套 or 帮腔 (曲牌体全本／牡丹亭／桃花扇／窦娥冤／救风尘／长生殿／巴山秀才／唱段表／结构表).
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Chinese opera playwriting for the qupai (曲牌体) system — 元杂剧, 明清传奇, 昆曲, 川剧高腔, where sung text is filled into fixed tune patterns (填词) rather than built from paired lines varied by metre. Covers stage vs study (李渔 vs 吴梅/王季烈), the 清曲/剧曲 switch, the zaju branch (四折一楔子, one 宫调 and one rhyme per act, 一人主唱, 题目正名), the chuanqi branch (出, 副末开场, 南北合套, 集唐下场诗), tune-filling (格律, 前腔/换头/幺, 衬字, 务头, 尾声, 四十禁), the seventeen 宫调 and their affects, 套数, 排场 alternation, the spoken-to-sung cue, 帮腔, adaptation, and modern practice. From 李渔《闲情偶寄》, 吴梅《顾曲麈谈》《曲学通论》, 王季烈《螾庐曲谈》, 孔尚任's 凡例, 关汉卿, 汤显祖, 魏明伦. Use when writing or revising a 曲牌体 script, choosing a 宫调 for an emotion, laying out a 套数, filling one tune pattern, writing a zaju act or a chuanqi scene, cutting an old 传奇 into a playable version, writing a modern qupai opera, or judging whether a famous script's prosody may be copied. Not for 京剧/豫剧/越剧, which are the banqiang system; see sw-chinese-opera-banqiang.
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Use when asked 信用证审证, 信用证审单, 审核信用证条款, 单证不符点, L/C 软条款, 交单前检查, or check a letter of credit or a set of export documents against it for a Chinese exporter. Produces an L/C term review (dates, amounts, shipment, documents, soft clauses) with what to ask the buyer to amend, and a document-by-document discrepancy checklist (invoice, bill of lading, packing list, insurance, certificate of origin, inspection) with the relevant UCP 600 articles, all marked to confirm with the bank's documentary credit team. Not legal or banking advice.
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Prepare for China's annual individual income tax reconciliation (个税年度汇算): check income, deductions and special additional deductions, compare the two treatments of a year-end bonus, and estimate the refund or amount to pay before filing in the 个人所得税 app. Use when asked 个税汇算怎么弄, 年终奖单独计税还是合并, 我能退多少税, 专项附加扣除, or how does China's annual tax reconciliation work. Produces a filing checklist, the deductions the person may be missing, a bonus comparison, the estimate with workings, and deadlines. Not tax advice.
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Write a fundraising case for support that makes donors want to give. Use when asked to write a case for support, a fundraising case statement, a major-gift or campaign case, or the core argument for a donation appeal. Produces a persuasive case — the need, your solution and why you, the impact a gift makes, specific funding opportunities with amounts, and a clear ask — donor-centred, not org-centred.
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Organize the people and information involved in caring for someone — family, doctors, helpers — so care doesn't fall through the cracks or all land on one person. Use when asked help me coordinate care for, organize caregiving for my parent, set up a care system, or I'm drowning coordinating everyone. Produces a map of who does what (medical, daily, financial, emotional), a shared-information system so everyone's on the same page, a way to divide tasks fairly among family, a communication rhythm, and how to keep the key information (meds, contacts, wishes) in one accessible place — turning caregiving chaos into a coordinated effort.
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通用 Web API 数据采集、Node.js/Python 协议调用与前端签名分析。 使用 Camoufox MCP 捕获请求、调试 Hook、分析混淆/JSVMP/WASM， 交付可验证的采集程序，支持分页、断点续采和接口改版回归。 用于自有或已授权接口；微信小程序 wxapkg 解包使用对应小程序技能。
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Use when deciding whether a project fits Agricultural Systems (AgSy) and which article type to target. AgSy is a systems-science journal, so the test is a genuine systems question — interactions among components, across hierarchical levels (field → farm → landscape → region → food system), trade-offs, and emergent behavior — analyzed with integrated modelling, NOT a single-factor field trial. Helps frame the question; it does not collect data.
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Use when the front end of an Academy of Management Journal (AMJ) manuscript needs to engage the right literatures and stake a clear position in an ongoing theoretical conversation. Positions the paper among theories; it does not derive the hypotheses (amj-theory-development) or write the contribution paragraph (amj-contribution-framing).
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Monitor web sources for Series A-C funding announcements. Aggregates signals from TechCrunch, Crunchbase (via web search), Twitter, Hacker News, and LinkedIn. Filters by stage, amount, and industry. Returns qualified recently-funded companies ready for outreach.
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Analyze ad campaign performance data (Google, Meta, LinkedIn) to identify what's working, what's wasting budget, and specific cut/scale/test recommendations. Runs statistical analysis, funnel diagnostics, and multi-channel budget reallocation with specific dollar-amount shift recommendations and scenario modeling.
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Nominates and assesses CRISPR off-target sites genome-wide. Enumerates candidate sites by mismatch and bulge tolerance with Cas-OFFinder/CRISPRitz, ranks them with the published CFD score (SpCas9-only, relative ranker) or MIT/CRISTA/energy models, runs variant-aware screening against gnomAD/individual genomes (CRISPRme), and frames the empirical genome-wide discovery assays (GUIDE-seq, CIRCLE-seq, CHANGE-seq, DISCOVER-seq, Digenome-seq) and high-fidelity nuclease choice (HiFi Cas9, Sniper-Cas9, eSpCas9, SpCas9-HF1). Use when assessing guide RNA specificity, choosing among candidate guides, screening a therapeutic guide against population variation, or planning empirical off-target validation. Distinguishes predicted vs detected vs validated. On-target activity scoring and deaminase (Cas-independent) base/prime-editor off-targets are separate skills.
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Detects TAD boundaries from balanced Hi-C contact matrices via the diamond-window insulation score (cooltools insulation) and HiCExplorer hicFindTADs, returning a continuous log2 insulation track, valley-prominence boundary_strength, and Li/Otsu-thresholded is_boundary flags across a list of window sizes. Covers the multi-scale window sweep (sub-TAD to compartment-domain), why the boundary is reproducible but the domain partition is not, cross-condition comparison via differential SCORE not differential partition, and the insulation-vs-compartment orthogonality. Use when calling TADs or domain boundaries, computing insulation scores, choosing a window size, ranking boundary strength, comparing boundaries across conditions, or annotating CTCF-backed boundaries; route domain rendering to hic-visualization and boundary-feature overlap to genome-intervals.
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Delimits putative species boundaries from molecular data within the de Queiroz 2007 unified-lineage framework using ASAP (Puillandre 2021 successor to ABGD), mPTP C++ (Kapli 2017 successor to bPTP; bPTP is Python NOT R), GMYC single/multi-threshold (Pons 2006; Fujisawa 2013), multilocus BPP v4 with prior calibration from data (NOT defaults; Yang 2015), SNAPP + BFD* for SNP delimitation, DELINEATE (Sukumaran 2021) speciation-process modeling to address Sukumaran & Knowles 2017 PNAS critique that MSC delimits structure not species, integrative-taxonomy congruence (Padial 2010; Carstens 2013), Dsuite for introgression testing before sister claims (Malinsky 2021), and Meyer & Paulay 2005 barcoding-gap-absence caveat. Use when delineating species from DNA barcoding data, resolving cryptic complexes, choosing among ASAP/mPTP/BPP/DELINEATE, calibrating BPP priors, distinguishing introgression from ILS, or applying the Sukumaran-Knowles oversplitting correction.
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Simulate transcription factor perturbation effects on cell state in silico with CellOracle and Dynamo, and predict transcriptional responses to genetic perturbations with GEARS, scGen, and CPA. Covers the direction-not-magnitude principle, local-linear validity, the GRN/velocity error it inherits, baseline discipline (mean and additive baselines), and the validation gap. Use when predicting TF knockout or overexpression effects, ranking driver TFs for fate transitions, or planning perturbation experiments. For GRN construction see multiomics-grn; for experimental Perturb-seq see single-cell/perturb-seq.
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Tests genotype-environment associations and identifies adaptive loci while correcting for the four-confound landscape (structure, demography, background selection, sampling design) using LFMM2 with mandatory K via sNMF cross-entropy elbow (LEA 3), BayPass Core/AUX/C2/IS with Omega covariance matrix, RDA / pRDA for polygenic adaptation (Forester 2018; requires imputed genotypes), OutFLANK with trimmed FST null, pcadapt, gradient forests (Ellis-Smith-Pitcher 2012, NOT mis-cited Ellis-Manel), Capblancq & Forester 2021 RDA Swiss-army-knife, genomic-offset prediction with Lind & Lotterhos 2025 three-regime caveat, Lotterhos-Whitlock sampling optima, Wang & Bradburd 2014 IBD vs IBE, and Circuitscape + ResistanceGA. Use when identifying adaptive loci across gradients, choosing K for LFMM2, deciding among GEA methods, predicting maladaptation with the novel-environment caveat, distinguishing IBD vs IBE, or optimizing sampling design.
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Build forest plots (HR, OR, RR, beta-coefficient summaries with CIs) and funnel plots (meta-analysis publication-bias diagnostics) using forestplot, metafor, ggforest, and MendelianRandomization with proper axis-scaling, summary-diamond placement, subgroup nesting, and Egger / trim-and-fill asymmetry tests. Use when summarizing effects across subgroups, trials, or instruments — meta-analysis, Mendelian randomization, subgroup HRs.
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Infer integer allele-specific copy number, tumor purity, and ploidy from tumor sequencing by jointly modeling read depth (logR) and B-allele frequency (BAF) with ASCAT, Sequenza, FACETS, PURPLE, and PureCN (tumor-only). Covers the purity-ploidy identifiability problem, the diploid-baseline (dipLogR) anchor, major/minor copy number, loss of heterozygosity, sunrise/contour fit diagnostics, and reconciliation of conflicting fits. Use when tumor analysis needs absolute copy number rather than relative log2, when estimating purity and ploidy, calling LOH or copy-neutral LOH, resolving whole-genome doubling, running tumor-only allele-specific calling, or choosing among ASCAT, Sequenza, FACETS, and PureCN.
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Cross-method decision tree for calling hits in pooled CRISPR screens. Catalogs statistical models (MAGeCK RRA, MAGeCK MLE, BAGEL2, drugZ, JACKS, Chronos, CERES), experimental designs each is built for, failure modes outside design domain, reconciliation when methods disagree, multiple-testing and effect-size thresholds, the order of operations (count -> QC -> CN-correct -> hit-call -> validate), the second-best-sgRNA conservative rule, and consensus-hit strategy. Use when choosing among MAGeCK / BAGEL2 / drugZ / JACKS / Chronos for a given design, reconciling disagreement across two or three methods on the same screen, deciding whether to require consensus, gating downstream validation by hit-confidence tier, or interpreting unstable hit lists across reruns.
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