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概要と使いどころ
Run programmatic Tavily search and extraction while filtering raw results outside the main agent context. Use for multi-step or high-volume research where titles, snippets, and selected passages should be curated before synthesis.
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Voice agents represent the frontier of AI interaction - humans speaking naturally with AI systems. The challenge isn't just speech recognition and synthesis, it's achieving natural conversation flow with sub-800ms latency while handling interruptions, background noise, and emotional nuance. This skill covers two architectures: speech-to-speech (OpenAI Realtime API, lowest latency, most natural) and pipeline (STT→LLM→TTS, more control, easier to debug). Key insight: latency is the constraint. Hu
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Expert in building voice AI applications - from real-time voice agents to voice-enabled apps. Covers OpenAI Realtime API, Vapi for voice agents, Deepgram for transcription, ElevenLabs for synthesis, LiveKit for real-time infrastructure, and WebRTC fundamentals. Knows how to build low-latency, production-ready voice experiences. Use when: voice ai, voice agent, speech to text, text to speech, realtime voice.
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Comprehensive toolkit for product managers including RICE prioritization, customer interview analysis, PRD templates, discovery frameworks, and go-to-market strategies. Use for feature prioritization, user research synthesis, requirement documentation, and product strategy development.
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Deep multi-source research synthesis — web, academic, patent, and internal KB cross-referencing
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Turn the current conversation into a PRD and publish it to the project issue tracker — no interview, just synthesis of what you've already discussed.
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Synthesize scientific evidence into a claim-to-source matrix, distinguish primary evidence from interpretation, assess disagreement and study limitations, and produce a calibrated research summary.
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Deep literature review — PubMed, EuropePMC, bioRxiv preprints, citation networks, evidence synthesis. Disambiguates queries, runs collision-aware searches, grades evidence T1-T4, and produces structured reports. Use for systematic literature review, meta-analysis evidence collection, and detailed answer-with-citations workflows.
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Meta-analysis / evidence synthesis — pool effect sizes across studies (odds ratios, risk ratios, hazard ratios, mean differences, correlations, GWAS betas) with fixed- or random-effects models, quantify heterogeneity (Q, I², τ²), and build a forest plot. Use when you have results from MULTIPLE studies and need a single pooled estimate, or to synthesize evidence from a systematic review / multiple GWAS / replicated experiments. Handles the error-prone effect-size + standard-error preparation (converting OR/HR/CI, two-group means±SD, proportions, and correlations into the (effect, SE) the pooling step needs).
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Organic chemistry reasoning guide for reaction product prediction, mechanism analysis (electrophilic/nucleophilic substitution, addition, elimination, pericyclic, radical), and spectroscopy interpretation (1H/13C NMR, IR, MS). Reasons from first principles (electron flow, kinetic vs thermodynamic) rather than pattern-matching named reactions. Use for organic synthesis problems and mechanism explanations.
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Find commercial sources for chemical compounds — PubChem/ChEMBL identity resolution then vendor catalog search across ZINC, Enamine, eMolecules, Mcule. Compares pricing, availability, and identifies purchasable analogs when an exact compound is not in stock. Use for chemical procurement, virtual library curation, and 'where can I buy X' questions for synthesis planning.
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PyTorch-native graph neural networks for molecules and proteins. Use when building custom GNN architectures for drug discovery, protein modeling, or knowledge graph reasoning. Best for custom model development, protein property prediction, retrosynthesis. For pre-trained models and diverse featurizers use deepchem; for benchmark datasets use pytdc.
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Search academic literature and generate, validate, or compare Knows paper sidecars. Use for claim/evidence analysis and literature synthesis.
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Technical research methodology with YAGNI/KISS/DRY principles. Phases: scope definition, information gathering, analysis, synthesis, recommendation. Capabilities: technology evaluation, architecture analysis, best practices research, trade-off assessment, solution design. Actions: research, analyze, evaluate, compare, recommend technical solutions. Keywords: research, technology evaluation, best practices, architecture analysis, trade-offs, scalability, security, maintainability, YAGNI, KISS, DRY, technical analysis, solution design, competitive analysis, feasibility study. Use when: researching technologies, evaluating architectures, analyzing best practices, comparing solutions, assessing technical trade-offs, planning scalable/secure systems.
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Designs and analyzes pooled prime-editor (PE) screens for installing precise genetic variants without bystander confounding. Covers pegRNA design with PRIDICT and PRIDICT2 (Mathis 2023/2024) for predicting per-pegRNA editing efficiency, pegRNA architecture (spacer + scaffold + PBS + RTT), PE2 / PE3 / PE3b / PEmax / PEAR variants, MOSAIC in situ saturation mutagenesis (Hsu JY et al 2024 bioRxiv), the PRIME pooled-screen methodology (Erwood/Doman 2023 Nat Biotechnol 41:885; ~3,699 ClinVar variant screens), chromatin context as a primary determinant of PE efficiency, scaffold-incorporation and indel byproduct quantification with CRISPResso2, and the cross-modal validation strategy of PE + base-editor screens for variant function. Use when designing a pegRNA library for variant installation, choosing between BE and PE for a specific edit, predicting pegRNA efficiency before library synthesis, analyzing PE screen output, distinguishing intended-edit from scaffold-incorporation, or scaling PE screens to thousands of variants.
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Capture the "why" behind technical choices to prevent architectural drift. Load when the user makes a major technical decision, chooses a library/framework, defines a system boundary, or changes a core architectural pattern. Also triggers on "record a decision", "write an ADR", "why did we do this", "document this architectural choice", or "architectural decision record". Supports `SYNTHESIS=true` mode for retrospective ADR backfill from observed repo state — used by `retroactive-project-setup` and any future backfill skill. Essential for long-term project maintainability and agent alignment.
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Search real-time news with bias scoring, get live stock/ETF/crypto data with AI analysis, ML options pricing, balanced news synthesis, and meme search via the Helium MCP server.
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Designs and analyzes pooled prime-editor (PE) screens for installing precise genetic variants without bystander confounding. Covers pegRNA design with PRIDICT and PRIDICT2 (Mathis 2023/2024) for predicting per-pegRNA editing efficiency, pegRNA architecture (spacer + scaffold + PBS + RTT), PE2 / PE3 / PE3b / PEmax / PEAR variants, MOSAIC in situ saturation mutagenesis (Hsu JY et al 2024 bioRxiv), the PRIME pooled-screen methodology (Erwood/Doman 2023 Nat Biotechnol 41:885; ~3,699 ClinVar variant screens), chromatin context as a primary determinant of PE efficiency, scaffold-incorporation and indel byproduct quantification with CRISPResso2, and the cross-modal validation strategy of PE + base-editor screens for variant function. Use when designing a pegRNA library for variant installation, choosing between BE and PE for a specific edit, predicting pegRNA efficiency before library synthesis, analyzing PE screen output, distinguishing intended-edit from scaffold-incorporation, or scaling PE screens to thousands of variants.
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Generate professional clinical decision support (CDS) documents for pharmaceutical and clinical research settings, including patient cohort analyses (biomarker-stratified with outcomes) and treatment recommendation reports (evidence-based guidelines with decision algorithms). Supports GRADE evidence grading, statistical analysis (hazard ratios, survival curves, waterfall plots), biomarker integration, and regulatory compliance. Outputs publication-ready LaTeX/PDF format optimized for drug development, clinical research, and evidence synthesis.
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End-to-end AI video generation - create videos from text prompts using image generation, video synthesis, voice-over, and editing. Supports OpenAI DALL-E, Replicate models, LumaAI, Runway, and FFmpeg editing.
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Expert web researcher using advanced search techniques and synthesis. Masters search operators, result filtering, and multi-source verification. Handles competitive analysis and fact-checking. Use PROACTIVELY for deep research, information gathering, or trend analysis.
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Use when user requests research requiring multiple sources, comprehensive analysis, or synthesis across topics - technical research, domain knowledge gathering, market analysis, or learning about complex subjects
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Perform complex, long-running research tasks using Gemini Deep Research Agent. Use when asked to research topics requiring multi-source synthesis, competitive analysis, market research, or comprehensive technical investigations that benefit from systematic web search and analysis.
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Precision Financial Insights - Analyze stocks, companies, and market sentiment using authoritative data. Powered by Yahoo Finance and enhanced with intelligent news synthesis by we-crafted.com/agents/financial-market-analysis - Buy CRAFTED_API_KEY in our website to start using
日本語の概要は準備中です。原文の説明を表示しています。