「guides」の検索結果

Guides agents through authoring BACKLOG.md and OpenSpec change folders. Use when running /cc-backlog or /cc:backlog, creating or appending backlog items, or preparing work for /cc-openspec. Delivery is skill openspec.

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API documentation workflow for generating OpenAPI specs, creating developer guides, and maintaining comprehensive API documentation.

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Interactive Flutter Widget implementation assistant that guides you through widget implementation decisions by asking structured questions about state management, widget type (screen/component), and state sharing. Use this skill when you need help determining the appropriate Flutter widget architecture for your implementation.

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Conversion-focused design that removes friction and guides users toward action through clarity, trust, and speed.

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Documentation, standardization, and governance of the Vue + shadcn-vue design system. Use when creating component documentation, auditing consistency, defining naming conventions, or generating usage guides for the team.

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Establish and enforce coding standards, best practices, and architectural patterns across the codebase using linters, formatters, and code review processes. Use when setting up ESLint/Prettier, configuring linting rules, creating code style guides, implementing pre-commit hooks, establishing naming conventions, enforcing TypeScript strict mode, maintaining consistency, conducting architecture reviews, or defining team coding standards.

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Create and maintain comprehensive brand guidelines including visual identity, tone of voice, messaging, color palettes, typography, and usage rules for consistent brand expression. Use when establishing brand identity, creating style guides, defining visual standards, setting tone of voice, creating brand assets, or ensuring brand consistency.

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Initialize an Adobe App Builder project end-to-end without Developer Console UI clicks. Creates the Console project and workspace, subscribes APIs (including those needing a product profile), maps user intent to the right template, runs non-interactive `aio app init`, and guides post-init customization. Use whenever the user mentions creating an App Builder app, scaffolding a project, `aio app init`, setting up an Experience Cloud extension, adding actions or web assets, creating a Console project or workspace, adding APIs, or bootstrapping App Builder — even if they don't say "App Builder". Also for SPA templates, AEM extensions, API Mesh, Asset Compute workers, and MCP server projects. Also handles debugging init failures — template not found, `aio app init` hangs or times out, Node version mismatches, npm install failures, post-init build errors, `aio login` issues, `aio app run` showing nothing, or `aio console project create` / `workspace create` / `workspace api add` errors.

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Guides Rust performance optimization. Use when profiling, benchmarking, reducing allocations, improving cache locality, choosing between rayon/async/threads, or applying SIMD/parallelism.

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Guides generic vs trait object decisions in Rust. Use when choosing between static and dynamic dispatch, designing traits, handling E0277/E0038, or deciding between enum and dyn Trait.

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Guides type-driven design in Rust. Use when encoding invariants in types, applying newtype pattern, implementing type state machines, using PhantomData, or making invalid states unrepresentable.

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Guides concurrency and async decisions in Rust. Use when encountering Send/Sync errors (E0277), choosing between threads vs async, designing shared state, or debugging deadlocks.

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Guides Rust error handling strategy. Use when choosing between Result/Option/panic, using anyhow vs thiserror, propagating errors with ?, or designing custom error types.

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Guides ownership, borrowing, and lifetime decisions in Rust. Use when encountering E0382, E0597, E0506, E0507, move errors, or when designing data ownership.

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Deprecate APIs, features, or systems safely — announce, migrate consumers, sunset on a timeline, and document alternatives. Load when removing an old API, migrating users between implementations, sunsetting a feature, or the user asks about deprecation policy, migration guides, or breaking changes. Not for deleting dead code with zero consumers (use code-simplification). Distinct from meta `deprecate-skill` (skill library retirement).

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Orchestrate one or more thinking frameworks to work through any problem, decision, document, or idea rigorously. Diagnoses which frameworks fit — inversion, pre-mortem, assumption-mapping, socratic, adversarial-hat — then guides the user through them in the right sequence. Load when the user asks for deep thinking, says "help me think through this properly", "apply your best thinking frameworks", "I need to think carefully before deciding", or "what thinking tools should I use here". Also the entry point for any complex problem where the right framework is unclear. Covers product decisions, engineering tradeoffs, personal decisions, strategy, creative challenges — any domain.

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Guides for configuring Prisma with different database providers (PostgreSQL, MySQL, SQLite, MongoDB, etc.). Use when setting up a new project, changing databases, or troubleshooting connection issues. Triggers on "configure postgres", "connect to mysql", "setup mongodb", "sqlite setup".

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Use this skill when the user requests to generate, create, or improve documentation for code, APIs, libraries, repositories, or software projects. Supports README generation, API reference documentation, inline code comments, architecture documentation, changelog generation, and developer guides. Trigger on requests like "document this code", "create a README", "generate API docs", "write developer guide", or when analyzing codebases for documentation purposes.

日本語の概要は準備中です。原文の説明を表示しています。

API documentation workflow for generating OpenAPI specs, creating developer guides, and maintaining comprehensive API documentation.

日本語の概要は準備中です。原文の説明を表示しています。

Nominates and assesses CRISPR off-target sites genome-wide. Enumerates candidate sites by mismatch and bulge tolerance with Cas-OFFinder/CRISPRitz, ranks them with the published CFD score (SpCas9-only, relative ranker) or MIT/CRISTA/energy models, runs variant-aware screening against gnomAD/individual genomes (CRISPRme), and frames the empirical genome-wide discovery assays (GUIDE-seq, CIRCLE-seq, CHANGE-seq, DISCOVER-seq, Digenome-seq) and high-fidelity nuclease choice (HiFi Cas9, Sniper-Cas9, eSpCas9, SpCas9-HF1). Use when assessing guide RNA specificity, choosing among candidate guides, screening a therapeutic guide against population variation, or planning empirical off-target validation. Distinguishes predicted vs detected vs validated. On-target activity scoring and deaminase (Cas-independent) base/prime-editor off-targets are separate skills.

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Designs pegRNAs and nicking guides for prime editing (PE) -- choosing the nick/strand, tuning the primer-binding site (PBS) and reverse-transcription template (RTT) as a per-locus panel, selecting the PE system (PE2/PE3/PE3b/PE4/PE5/PEmax/PE7), adding MMR-evading and PAM-disrupting silent edits, appending epegRNA 3' motifs (tevopreQ1/mpknot), and ranking with PRIDICT/DeepPrime. Covers twinPE/PASTE for large insertions and the prime-vs-base-editing decision. Use when designing a scarless point mutation, small insertion/deletion, or any of the 12 base conversions without a double-strand break, when efficiency is low and MMR inhibition or pegRNA stabilization is needed, or when routing a large insertion to an integrase method. Generic guide scoring and base editing are separate skills.

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Designs and ranks guide RNAs (sgRNAs) for CRISPR-Cas9/Cas12a gene knockout by scanning a target for PAM sites (NGG SpCas9, NNGRRT SaCas9, TTTV Cas12a, NG SpCas9-NG, near-PAMless SpRY), enumerating candidate spacers, applying hard filters (Pol-III TTTT terminator, 5' G, GC), ranking on-target activity with the context-appropriate model (Rule Set 2/Azimuth for U6/lentiviral, CRISPRscan for T7/embryo, DeepHF for high-fidelity variants, DeepCpf1 for Cas12a), and predicting the indel/frameshift outcome (Bae out-of-frame score, inDelphi, FORECasT, Lindel). Use when selecting sgRNAs to knock out a gene, choosing a nuclease/PAM for a constrained locus, picking which exon to target, or shortlisting guides before an off-target check. Off-target specificity, base/prime editing, and HDR donors are separate skills.

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Designs cytosine (CBE, C-to-T) and adenine (ABE, A-to-G) base-editor guides by positioning the target base at the activity-peak of the editing window (protospacer positions ~5-7, PAM-distal numbering), minimizing bystander edits for product purity, reading dinucleotide context (APOBEC1 TC favored / GC disfavored), and selecting the editor variant (BE4max, ABEmax, ABE8e, YE1/SECURE, TadCBE, CGBE, SpG/SpRY-BE). Covers knockout by premature stop (CRISPR-STOP/iSTOP) and splice-site disruption, the three off-target classes (Cas-dependent, Cas-independent DNA, RNA), outcome prediction (BE-Hive/DeepBE), and the base-vs-prime-vs-HDR decision. Use when installing a transition mutation without a double-strand break, knocking out a gene without indels, or choosing CBE vs ABE. Generic guide scoring, prime editing, and HDR donors are separate skills.

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Compose multi-panel publication figures with patchwork, cowplot, gridExtra (R), or matplotlib GridSpec/subfigures (Python) including shared axes/legends/guides collection, panel labels in Nature/Cell convention, and journal-spec sizing. Covers patchwork ≥1.2.0 axes='collect' feature, Type-42 font embedding, and the cairo_pdf save path. Use when composing 2+ subpanels into a single figure for journal submission.

日本語の概要は準備中です。原文の説明を表示しています。