257 件 ・ 関連度順
概要と使いどころ
Build and extend the core Pump SDK — an offline-first TypeScript SDK that constructs Solana TransactionInstructions for token creation, buying, selling, migration, and creator fee collection across three on-chain programs (Pump, PumpAMM, PumpFees).
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Read-only query methods for PumpFun claims — unclaimed token rewards, creator vault balances, volume accumulators, distributable fees, and current-day token previews across Pump and PumpAMM programs.
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Use when the user asks to "monitor brand mentions", "set up social listening", "did anything spike about us this week", or "watch these accounts for buying triggers"; runs always-on keyless listening — a versioned listening-query architecture (brand variants incl. misspellings and 中文 names, exclusion terms, per-source syntax for HN Algolia / Bluesky / GDELT / Tavily), a mention sweep with six-class triage (crisis / bug / lead / praise / question / spam) each routed with an SLA, a 7-day rolling baseline with spike flags (the crisis trigger input), a B2B trigger watchlist (funding / hiring / launch signals), and an explicit coverage disclosure where X/IG/TikTok/LinkedIn/小红书 numbers are proxy-labeled, never Measured. Not for launch-window telemetry (T-0→T+30 rank and review polling) — use launch-monitor. 舆情监听/品牌提及监测/基线突刺/触发信号
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Use when the user asks to "build email segments from my list", "make engaged / lapsed / RFM segments", "set up cart-abandoner or lifecycle-stage audiences", or "build a suppression list of unsubscribes and bounces"; turns the user's OWN list/CRM/GA4/ecommerce export into behavioral, attribute, and lifecycle-stage segments plus a suppression list, with per-segment sizes labeled Measured/Estimated, informing the SEND E (Engagement/targeting) dimension. Not for scoring EQS or running vetoes — use email-quality-auditor; not for authentication or spam-content checks — use deliverability-qa. 邮件列表分群/生命周期分群/抑制名单/流失召回
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Use when the user asks to "watch my list health over time", "flag decaying / unengaged subscribers on a schedule", "why is my open rate drifting down / bounces creeping up", or "build me a re-permission and prune worklist"; runs the scheduled SEND list-decay + suppression-drift watch — an engagement-recency cohort read (30/90/180/365-day), hard-bounce and spam-complaint trend vs benchmark, suppression-list growth/leakage check, and a segmented re-permission / sunset / prune worklist tied to SEND S (list hygiene) and E (engagement-decay) sub-items. Not for the one-time pre-send authentication pre-flight — use deliverability-qa; not for the consent/suppression record itself — use consent-registry; not for computing the EQS or enforcing vetoes — use email-quality-auditor. 邮件列表健康度监控/退订漂移/沉睡用户清理
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Use when the user asks to "build our social crisis protocol", "mentions are exploding — what do we do first", or "when do we pause the posting queue"; produces a 1-5 severity ladder with tunable Estimated trigger thresholds (mention-velocity multiples vs the 7-day listening baseline, sentiment flip, journalist/regulator contact, employee-conduct class), the first-mechanical-action rule — pause ALL scheduled posts AND paid amplification, with dated state markers dropped to the channels proposal protocol and reconciled post-incident — a pre-approved holding-statement library with committed update cadences, when-NOT-to-post rules, a spokesperson/approval matrix, and a post-crisis retro template; re-runs the social-quality-auditor pre-publish gate before un-pausing the queue. Not for email deliverability incidents (blocklist, spam-rate spikes) — use deliverability-qa; inside a launch window launch-day-conductor owns incident handling. 社媒危机预案/暂停队列/声明库/发言人矩阵
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Use when the user asks to "run a deliverability pre-flight before I send", "check my SPF/DKIM/DMARC/BIMI", "why am I landing in spam / promotions", or "score my sender reputation and list hygiene"; runs the ONE-TIME pre-send SEND S1 authentication pre-flight and builds the SEND S (Sender-integrity / Deliverability) evidence read — DNS + DMARC-RUA auth, domain/IP reputation, inbox placement, content/link/render, and point-in-time bounce/complaint hygiene — using Pass/Partial/Fail/Unknown/N/A states and scoring only at complete applicable coverage. Not for the recurring hygiene trend — use list-hygiene-monitor; not for final EQS or veto verdicts — use email-quality-auditor; not for segments/suppression lists — use list-segment-builder. 邮件送达率预检/SPF DKIM DMARC认证/发件域声誉
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Use when the user asks to "write the email", "draft subject lines", or "build email creative"; produces the pre-click unit — subject-line variants + preheader, body copy, one clear CTA, and a plain-text alt — message-matched to the destination page and claims-ledger-aware. Not for pre-scoring or ranking subject-line variants (spam/truncation/render pre-score) — use subject-line-lab; not for scoring the email or computing EQS — use email-quality-auditor; not for the multi-step flow — use email-sequence-designer; not for the A/B test plan — use send-experiment-designer. 邮件文案/主题行/邮件创意
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Email marketing operations and automation for B2B SaaS. Use this skill for newsletter strategy, email automation sequences, lifecycle campaigns, nurture workflows, onboarding sequences, deliverability optimization, email copywriting, lead scoring, marketing automation platform setup, and cold-email sending infrastructure — secondary sending domains, SPF/DKIM/DMARC, and domain warmup. Also triggers on: email, newsletter, drip campaign, lifecycle, nurture, onboarding sequence, deliverability, email automation, lead scoring, marketing automation, our emails are going to spam, SPF, DKIM, DMARC, sender reputation, sending domain, cold email domains, domain warmup, mailbox setup, blacklist, bounce rate.
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Plan FriendlyBet ethical growth, SEO, README positioning, open-source contribution paths, self-hosting story, public trust, and discovery without ads, trackers, spam, or dark patterns. Use for repo-facing docs, growth strategy, launch positioning, SEO pages, contributor onboarding, or public messaging.
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Use when working with Calico — calico networking and security management for Kubernetes. Covers network policy enforcement, BGP configuration, IPAM management, Felix agent status, Typha health, WireGuard encryption, and global network sets. Use when managing Calico network policies, debugging routing issues, configuring BGP peering, or monitoring Felix/Typha health.
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Time-blind friendly planning, executive function support, and daily structure for ADHD brains. Specializes in realistic time estimation, dopamine-aware task design, and building systems that actually work for neurodivergent minds.
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Serverless form handling on Netlify-hosted sites — detects HTML forms at deploy time, stores submissions, filters spam, and sends notifications. Use when adding a contact form, lead-capture form, file-upload form, or newsletter signup to a Netlify site; wiring AJAX form submission; setting up a custom thank-you page; adding a honeypot or reCAPTCHA to a form; getting forms working in Next.js, Nuxt, SvelteKit, Astro, or Gatsby; reading form submissions via the Netlify API; or debugging missing submissions and forms that silently fail to register.
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Email has the highest ROI of any marketing channel. $36 for every $1 spent. Yet most startups treat it as an afterthought - bulk blasts, no personalization, landing in spam folders. This skill covers transactional email that works, marketing automation that converts, deliverability that reaches inboxes, and the infrastructure decisions that scale. Use when: keywords, file_patterns, code_patterns.
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Run a Busabase-backed sales prospecting and first-touch outreach desk with a bundled Hono App-in-Skill deployable to AirApp. Use whenever the user invokes $kelly-sales-outreach or /kelly-sales-outreach, wants to enter a product or service and discover its ideal customers, asks to continuously find target accounts or public business contacts, needs evidence-based ICP scoring and personalized outreach drafts, or wants to review and send cold outreach safely. Four subcommands - setup, profile, research, send - plus the desk itself. Every first-touch message requires human approval; one company receives one initial email; guessed addresses, purchased lists, secret exposure, automated spam, and unreviewed external sends are forbidden.
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Outbound email-marketing desk (Busabase App-in-Skill) for building segments, drafting campaigns, newsletters, and sequences, running pre-send deliverability and subject-line QA, and approving every send before it is scheduled. Structured around the SEND discipline — Setup, Engage, Nurture, Deliver — with an email-quality-auditor gate (EQS score + SHIP/FIX/BLOCK verdict). Use when the user invokes $kelly-campaigns or /kelly-campaigns, or mentions email marketing, campaigns, newsletters, drip/welcome/win-back sequences, broadcasts, segments, subject-line A/B tests, deliverability (SPF/DKIM/DMARC/spam score/inbox placement), or wants to review and approve marketing email before it is sent. This is OUTBOUND marketing to a subscriber list, distinct from kelly-email inbox triage (incoming mail). 出站邮件营销：策划分群、起草营销活动 / 新闻邮件 / 邮件序列，发送前做可送达性与主题行质检，人工审批后再排期发送。
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Spearphishing targets specific individuals using personalized, researched content that bypasses generic spam filters. Email security gateways (SEGs) like Microsoft Defender for Office 365, Proofpoint,
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Designs donor/repair templates for precise CRISPR knock-ins -- choosing the format (ssODN, long-ssDNA/Easi-CRISPR, dsDNA/plasmid, AAV6), sizing homology arms, placing the cut within ~10 bp of the edit, and adding a mandatory codon-checked blocking (PAM/seed) mutation so the edited allele is not re-cut. Frames the HDR-vs-NHEJ-vs-MMEJ pathway competition, the MMEJ (PITCh) and homology-independent (HITI/HMEJ) alternatives for post-mitotic cells, ssODN strand/asymmetry choice, phosphorothioate end-protection, and ranked HDR enhancers. Use when designing a donor for a point mutation, epitope/fluorophore tag, allele replacement, or knock-in, or when HDR efficiency is low. Guide design and base/prime editing are separate skills.
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Designs pegRNAs and nicking guides for prime editing (PE) -- choosing the nick/strand, tuning the primer-binding site (PBS) and reverse-transcription template (RTT) as a per-locus panel, selecting the PE system (PE2/PE3/PE3b/PE4/PE5/PEmax/PE7), adding MMR-evading and PAM-disrupting silent edits, appending epegRNA 3' motifs (tevopreQ1/mpknot), and ranking with PRIDICT/DeepPrime. Covers twinPE/PASTE for large insertions and the prime-vs-base-editing decision. Use when designing a scarless point mutation, small insertion/deletion, or any of the 12 base conversions without a double-strand break, when efficiency is low and MMR inhibition or pegRNA stabilization is needed, or when routing a large insertion to an integrase method. Generic guide scoring and base editing are separate skills.
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Designs cytosine (CBE, C-to-T) and adenine (ABE, A-to-G) base-editor guides by positioning the target base at the activity-peak of the editing window (protospacer positions ~5-7, PAM-distal numbering), minimizing bystander edits for product purity, reading dinucleotide context (APOBEC1 TC favored / GC disfavored), and selecting the editor variant (BE4max, ABEmax, ABE8e, YE1/SECURE, TadCBE, CGBE, SpG/SpRY-BE). Covers knockout by premature stop (CRISPR-STOP/iSTOP) and splice-site disruption, the three off-target classes (Cas-dependent, Cas-independent DNA, RNA), outcome prediction (BE-Hive/DeepBE), and the base-vs-prime-vs-HDR decision. Use when installing a transition mutation without a double-strand break, knocking out a gene without indels, or choosing CBE vs ABE. Generic guide scoring, prime editing, and HDR donors are separate skills.
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Analyzes base-editing screens for variant function. Covers library design (Sanson 2020 GRACE, Hanna 2021 BRCA1/2 SNV scanning, Cuella-Martin 2021), CBE vs ABE chemistry choice (BE3/BE4 vs ABE7.10/ABE8.20/ABE8e), editing-window math (positions 4-8 from PAM-distal end, wider for ABE8e), bystander-edit quantification and the variant-call ambiguity it creates, sgRNA-efficiency filtering before hit calling, indel byproduct interpretation, the substitution-vs-indel diagnostic, variant annotation against ClinVar / COSMIC, and the Broad be-validation-pipeline. Use when designing a BE variant screen, choosing CBE vs ABE for a specific edit, interpreting bystander-confounded hits, distinguishing functional signal from indel artifact, integrating CRISPResso2 output with screen scoring, or deciding BE vs PE for SNV installation.
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Designs pooled sgRNA libraries for CRISPR knockout, interference (CRISPRi), activation (CRISPRa), Cas12a multiplex, base-editor, and prime-editor screens. Covers on-target scoring (Rule Set 2, Azimuth, DeepSpCas9, CRISPRon), off-target scoring (CFD, MIT), TSS-relative positioning for CRISPRi/a (Horlbeck, Dolcetto, Calabrese), PAM-variant chemistries, control-guide composition, oligo cloning architecture, and library QC. Use when choosing a genome-wide library (GeCKOv2 vs Avana vs Brunello vs TKOv3 vs Inzolia), designing a focused or paralog-focused custom library, picking CRISPRi vs CRISPRa TSS windows, deciding control-guide proportions, or diagnosing library skew and dropout in a freshly cloned pool.
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Reconstruct ancestral states at internal phylogenetic nodes for sequences (PAML codeml, IQ-TREE --ancestral, GRASP, FastML), discrete traits (corHMM hidden-rate Markov, ape::ace, phytools::make.simmap stochastic mapping, BayesTraits), and continuous traits (phytools::fastAnc, geiger Brownian/OU, RPANDA). Use when designing constructs for ancestral protein resurrection, tracing trait evolution along a tree, performing stochastic character mapping, testing models of trait evolution (BM vs OU vs EB), inferring ancestral genome content via Dollo or DTL reconciliation, or quantifying ancestral-state uncertainty for downstream comparative analyses.
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Discover RBP binding motifs from CLIP-seq peaks or single-nucleotide crosslink sites using HOMER, MEME/STREME, kpLogo, mCross (CL-position-registered motifs), PEKA (positional k-mer enrichment), RBPamp (affinity), and RNA Bind-n-Seq (RBNS) cross-validation. Use when characterizing RBP sequence specificity, registering motifs to crosslink positions, validating in vivo CLIP motifs against in vitro RBNS Kd, reconciling motif disagreements across tools, or correcting for the uracil crosslinking bias that contaminates raw CLIP motif logos.
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